Cellular profiles in the abomasal mucosa and lymph node during primary infection with Haemonchus contortus in sheep

Veterinary Immunology and Immunopathology

Volumn 75, Issue 1-2, 2000, Pages 109-120

  Balic, A ^a   Bowles, V M ^a   Meeusen, E N T ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Haemonchus contortus; Immune response; Lymph node; Nematode; Primary infection; Sheep

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL POPULATION; CONTROLLED STUDY; FLOW CYTOMETRY; HAEMONCHUS CONTORTUS; HISTOLOGY; IMMUNE RESPONSE; IMMUNOFLUORESCENCE; LAMB; LYMPH NODE; LYMPHOCYTE; MUCOSA; NEMATODIASIS; NONHUMAN; PRIMARY INFECTION; RUMINANT STOMACH; STOMACH MUCOSA;

ABOMASUM; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FLOW CYTOMETRY; HAEMONCHIASIS; INTESTINAL MUCOSA; LYMPH NODES; MICROSCOPY, FLUORESCENCE; SHEEP; SHEEP DISEASES;

HAEMONCHUS CONTORTUS; OVIS ARIES;

EID: 0034733850     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2427(00)00189-6     Document Type: Article

References (19)

1. Adams D.B., Beh K.J. Immunity acquired by sheep from an experimental infection with Haemonchus contortus. Int. J. Parasitol. 11:1981;381-386.
2. Almeria S., Canals A., Zarlenga D.S., Gasbarre L.C. Isolation and phenotypic characterization of abomasal mucosal lymphocytes in the course of a primary Ostertagia ostertagi infection in calves. Vet. Immunol. Immunopathol. 57:1997;87-98.
3. Barger I.A., Le Jambre L.F., Georgi J.R., Davies H.I. Regulation of Haemonchus contortus populations in sheep exposed to continuous infection. Int. J. Parasitol. 15:1985;529-533.
4. Behnke K.M., Wahid F.N., Grencis R.K., Bensmith A.W., Goyal P.K. Immunological relationships during primary infection with Heligmosomoides polygyrus(Nematospiroides dubius) - down-regulation of specific cytokine secretion (IL-9 and IL-10) correlates with poor mastocytosis and chronic survival of adult worms. Parasite Immunol. 15:1993;415-421.
5. Bowles V.M., Brandon M.R., Meeusen E. Characterization of local antibody responses to the gastrointestinal parasite Haemonchus contortus. Immunology. 84:1995;669-674.
6. Charleston W.A.G. Pathogenesis of experimental haemonchosis in sheep with special reference to the development of resistance. J. Comp. Pathol. 75:1965;55-67.
7. Gasbarre L.C. Ostertagia ostertagi: changes in lymphoid populations in the local lymphoid tissues after primary or secondary infection. Vet. Parasitol. 55:1994;105-114.
8. George J., Penner S.J., Weber J., Berry J., Claflin J.L. Influence of membrane Ig receptor density and affinity on B-cell signaling by antigen- Implications for affinity maturation. J. Immunol. 151:1993;5955-5965.
9. + T-cells abrogates genetic resistance to Haemonchus contortus in sheep. Immunology. 78:1993;43-49.
10. Grencis R.K., Entwistle G.M. Production of an interferon-gamma homologue by an intestinal nematode: functionally significant or interesting artefact? Parasitology. 115:1997;S101-S105.
11. Halper J., Fu S.M., Wang C.Y., Winchestor R., Kunkel H.G. Patterns of expression of Ia-like antigens during the terminal stages of B-cell development. J. Immunol. 120:1978;1480-1484.
12. Huntley J.K., Newlands G.F., Miller H.R. The isolation and characterization of globule leucocytes: their derivation from mucosal mast cells in parasitized sheep. Parasite Immunol. 6:1984;371-390.
13. Kooyman F.N., Van Kooten P.J., Huntley J.F., MacKellar A., Cornelissen A.W., Schallig H.D. Production of a monoclonal antibody specific for ovine immunoglobulin E and its application to monitor serum IgE responses to Haemonchus contortus infection. Parasitology. 114:1997;395-406.
14. Mackay C.R., Marston W., Dudler L., Spertini O., Tedder T., Hein W. Tissue-specific migration pathways by phenotypically distinct subpopulations of memory T-cells. Eur. J. Immunol. 22:1992;887-895.
15. Meeusen E., Gorrell M.D., Rickard M.D., Brandon M.R. Lymphocyte subpopulations of sheep in protective immunity to Taenia hydatigena. Parasite Immunol. 11:1989;169-181.
16. Miller H.R. The protective mucosal response against gastrointestinal nematodes in ruminants and laboratory animals. Vet. Immunol. Immunopathol. 6:1984;167-259.
17. Salman S.K., Duncan J.L. The abomasal histology of worm-free sheep given primary and challenge infections of Haemonchus contortus. Vet. Parasitol. 16:1984;43-54.
18. Schallig H.D., van Leeuwen M.A., Hendrikx W.M. Isotype-specific serum antibody responses of sheep to Haemonchus contortus antigens. Vet. Parasitol. 56:1995;149-162.
19. Stewart D.F. Studies on the resistance of sheep to infestation with Haemonchus contortus and Trichostrongylus spp. and on the immunological reactions of sheep exposed to infestation. V. The nature of the self-cure phenomenon. Aust. J. Agric. Res. 4:1953;1000-1017.