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Volumn 65, Issue 13, 2000, Pages 3982-3996

Synthesis of enantiopure 3-quinuclidinone analogues with three stereogenic centers: (1S,2R,4S)- and (1S,2S,4S)-2-(hydroxymethyl)-1-azabicyclo[2.2.2]octan-5-one and stereocontrol of nucleophilic addition to the carbonyl group

(2) Frackenpohl, J a Hoffmann, H M R a

a LEIBNIZ UNIVERSITY HANNOVER (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 (HYDROXYMETHYL) 1 AZABICYCLO[2.2.2]OCTAN 5 ONE; 3 QUINUCLIDINOL; BICYCLO[2.2.2]OCTANE DERIVATIVE; CARBONYL DERIVATIVE; QUINUCLIDINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; BLOOD BRAIN BARRIER; BROMINATION; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; ENANTIOMER; NEUROTRANSMITTER RELEASE; STEREOCHEMISTRY; SYNTHESIS;

INDICATORS AND REAGENTS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; QUINUCLIDINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034733136 PISSN: 00223263 EISSN: None Source Type: Journal
DOI: 10.1021/jo9919815 Document Type: Article

Times cited : (18)

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