Inactivation of cysteine proteases by (acyloxy)methyl ketones using S'- P' interactions

Biochemistry

Volumn 39, Issue 21, 2000, Pages 6498-6502

  Dai, Yong ^a,b   Hedstrom, Lizbeth ^a   Abeles, Robert H ^a  

^a BRANDEIS UNIVERSITY   (United States)

^b Instrumentation Laboratory   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; INTERLEUKIN 1BETA CONVERTING ENZYME; KETONE; PAPAIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL REACTION; ENZYME ANALYSIS; ENZYME INACTIVATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; PRIORITY JOURNAL; PROTEIN INTERACTION;

ANIMALS; CASPASE 1; CATHEPSIN B; CATTLE; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DRUG DESIGN; KETONES; KINETICS; PAPAIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034732951     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0002378     Document Type: Article

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