메뉴 건너뛰기




Volumn 10, Issue 2, 2000, Pages 232-235

Random changes of amino acid residues with expected frequency by saturated point mutagenesis

Author keywords

Mutually Primed Synthesis; Random Saturation Mutagenesis; Spiked Degenerate Oligonucleotide (Oligo)

Indexed keywords

SACCHAROMYCES CEREVISIAE;

EID: 0034732404     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10059-000-0232-0     Document Type: Article
Times cited : (2)

References (14)
  • 1
    • 0023572209 scopus 로고
    • Human proto-oncogene c-jun encodes a DNA-binding protein with structural and functional properties of transcription factor AP-1
    • Bohmann, D., Bos, T. J., Admon, A., Nishimura, T., Vogt, P. K., and Tjian, R. (1987) Human proto-oncogene c-jun encodes a DNA-binding protein with structural and functional properties of transcription factor AP-1. Science 238, 1386-1392.
    • (1987) Science , vol.238 , pp. 1386-1392
    • Bohmann, D.1    Bos, T.J.2    Admon, A.3    Nishimura, T.4    Vogt, P.K.5    Tjian, R.6
  • 2
    • 0027049805 scopus 로고
    • The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted a helices: Crystal structure of the protein-DNA complex
    • Ellenberger, T., Brandi, C., Struhl, K., and Harrison, S. (1992) The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted a helices: crystal structure of the protein-DNA complex. Cell 71, 1223-1237.
    • (1992) Cell , vol.71 , pp. 1223-1237
    • Ellenberger, T.1    Brandi, C.2    Struhl, K.3    Harrison, S.4
  • 3
    • 0029872691 scopus 로고    scopus 로고
    • Mutations in target DNA elements of yeast HAP1 modulate its transcriptional activity without affecting DNA binding
    • Ha, N., Hellauer, K., and Turcotte, B. (1996) Mutations in target DNA elements of yeast HAP1 modulate its transcriptional activity without affecting DNA binding. Nucleic Acids Res. 24, 1463-1459.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 1463-11459
    • Ha, N.1    Hellauer, K.2    Turcotte, B.3
  • 4
    • 0022551258 scopus 로고
    • Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast
    • Hope, I. A. and Struhl, K. (1986) Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast. Cell 46 885-894.
    • (1986) Cell , vol.46 , pp. 885-894
    • Hope, I.A.1    Struhl, K.2
  • 5
    • 0023732753 scopus 로고
    • Mechanism of action of a yeast activator: Direct effect of GAL4 derivatives on mammalian TFIID-promoter interaction
    • Horikoshi, M., Carey, M. K., Kakidani, H., and Roeder, R. G. (1988) Mechanism of action of a yeast activator: direct effect of GAL4 derivatives on mammalian TFIID-promoter interaction. Cell 54, 665-669.
    • (1988) Cell , vol.54 , pp. 665-669
    • Horikoshi, M.1    Carey, M.K.2    Kakidani, H.3    Roeder, R.G.4
  • 6
    • 0029036735 scopus 로고
    • Determinants of half-site spacing preferences that distinguish AP-1 and ATF/CREB bZIP domains
    • Kim, J. and Struhl, K. (1995) Determinants of half-site spacing preferences that distinguish AP-1 and ATF/CREB bZIP domains. Nucleic Acids Res. 23, 2531-2547.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 2531-2547
    • Kim, J.1    Struhl, K.2
  • 7
    • 0027310483 scopus 로고
    • Adaptibility at the protein-DNA interface is an important aspect of sequence recognition by bZIP proteins
    • Kim, J., Tzamarias, D., Ellenberger, T., Harrison, S., and Struhl, K. (1993) Adaptibility at the protein-DNA interface is an important aspect of sequence recognition by bZIP proteins. Proc. Natl. Acad. Sci. USA 90, 4513-4517.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4513-4517
    • Kim, J.1    Tzamarias, D.2    Ellenberger, T.3    Harrison, S.4    Struhl, K.5
  • 8
    • 0031592748 scopus 로고    scopus 로고
    • Mutagenesis of the positively charged conserved residues in the 5′ exonuclease domain of Taq DNA polymerase
    • Kim, Y., Kim, J. S., Chang, C. S., Suh, S. W., and Lee, D. S. (1997) Mutagenesis of the positively charged conserved residues in the 5′ exonuclease domain of Taq DNA polymerase. Mol. Cells 7, 468-472.
    • (1997) Mol. Cells , vol.7 , pp. 468-472
    • Kim, Y.1    Kim, J.S.2    Chang, C.S.3    Suh, S.W.4    Lee, D.S.5
  • 9
    • 0023473632 scopus 로고
    • The use of random sequence oligonucleotides for determining consensus sequences
    • Oliphant, A. R. and Struhl, K. (1987) The use of random sequence oligonucleotides for determining consensus sequences. Methods Enzymol. 155, 568-582.
    • (1987) Methods Enzymol. , vol.155 , pp. 568-582
    • Oliphant, A.R.1    Struhl, K.2
  • 10
    • 0024365536 scopus 로고
    • Defining the sequencing specificity of DNA-binding proteins by selecting binding sites from random-sequence oligonucleotides: Analysis of yeast GCN4 protein
    • Oliphant, A. R., Brandi, C. J., and Struhl, K. (1989) Defining the sequencing specificity of DNA-binding proteins by selecting binding sites from random-sequence oligonucleotides: analysis of yeast GCN4 protein. Mol. Cell. Biol. 9, 2944-2949.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 2944-2949
    • Oliphant, A.R.1    Brandi, C.J.2    Struhl, K.3
  • 11
    • 0025940099 scopus 로고
    • Highly conserved residues in the bZIP domain of yeast GCN4 are not essential for DNA binding
    • Pu, W. T. and Struhl, K. (1991) Highly conserved residues in the bZIP domain of yeast GCN4 are not essential for DNA binding. Mol. Cell. Biol. 11, 4918-4926.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4918-4926
    • Pu, W.T.1    Struhl, K.2
  • 12
    • 0023918558 scopus 로고
    • The Jun oncoprotein, a vertebrate transcription factor, activates transcription in yeast
    • Struhl, K. (1988) The Jun oncoprotein, a vertebrate transcription factor, activates transcription in yeast. Nature 332, 649-650.
    • (1988) Nature , vol.332 , pp. 649-650
    • Struhl, K.1
  • 13
    • 0020491290 scopus 로고
    • Oligonucleotide-directed mutagenesis using M13-derived vectors: An efficient and general procedure for the production of point mutations in any fragment of DNA
    • Zoller, M. J. and Smith, M. (1982) Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA. Nucleic Acids Res. 10, 6487-6500.
    • (1982) Nucleic Acids Res. , vol.10 , pp. 6487-6500
    • Zoller, M.J.1    Smith, M.2
  • 14
    • 0022432579 scopus 로고
    • Analytical studies of "mixed sequence" oligo-deoxyribonucleotides synthesized by competitive coupling of either methyl- Or β-cyanoethyl-N,N-diisopropylaminophosphoramidite reagents including 2′-deoxy-inosine
    • Zon, G., Gallo, K. A., Samson, C. J., Shao, K.-L., Summers, M. F., and. Byrd, R. A. (1985) Analytical studies of "mixed sequence" oligo-deoxyribonucleotides synthesized by competitive coupling of either methyl- or β-cyanoethyl-N,N-diisopropylaminophosphoramidite reagents including 2′-deoxy-inosine. Nucleic Acids Res. 13, 8181-8196.
    • (1985) Nucleic Acids Res. , vol.13 , pp. 8181-8196
    • Zon, G.1    Gallo, K.A.2    Samson, C.J.3    Shao, K.-L.4    Summers, M.F.5    Byrd, R.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.