Effect of a neuronal sodium channel blocker on magnetic resonance derived indices of brain water content during global cerebral ischemia

Brain Research

Volumn 887, Issue 2, 2000, Pages 301-308

  Koinig, Herbert ^a,b   Williams, John P ^b   Quast, Michael J ^c   Zornow, Mark H ^b  

^a UNIVERSITY OF VIENNA   (Austria)

^b University of Texas Medical Branch School of Medicine   (United States)

^c UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Diffusion weighted magnetic resonance imaging; Global cerebral ischemia; Sodium channel blocker

Indexed keywords

EXCITATORY AMINO ACID; LAMOTRIGINE; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT;

ANIMAL EXPERIMENT; ARTICLE; BRAIN ISCHEMIA; BRAIN WATER; CONTROLLED STUDY; DIFFUSION COEFFICIENT; NEURORADIOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; REPERFUSION; WATER FLOW;

ANIMALS; BLOOD PRESSURE; BODY TEMPERATURE; BODY WATER; BRAIN; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY AMINO ACIDS; ISCHEMIC ATTACK, TRANSIENT; MAGNETIC RESONANCE IMAGING; RABBITS; REPERFUSION; SODIUM CHANNEL BLOCKERS; TIME FACTORS; TRIAZINES;

EID: 0034731644     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)03012-2     Document Type: Article

References (38)

1. Lamotrigine inhibits extracellular glutamate accumulation during transient global cerebral ischemia in rabbits
2. Changes in extracellular concentrations of glutamate, aspartate, glycine, dopamine, serotonin, and dopamine metabolites after transient global ischemia in the rabbit brain
3. Diffusion-weighted magnetic resonance imaging confirms marked neuroprotective efficacy of albumin therapy in focal cerebral ischemia
4. Imaging focal reperfusion injury following global ischemia with diffusion-weighted magnetic resonance imaging and 1H-magnetic resonance spectroscopy
5. MR of diffusion slowing in global cerebral ischemia
6. Use of diffusion-weighted MRI and neurological deficit scores to demonstrate beneficial effects of isradipine in a rat model of focal ischemia
7. Lamotrigine attenuates cortical glutamate release during global cerebral ischemia in pigs on cardiopulmonary bypass
8. Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain
9. Changes in the diffusion of water and intracellular metabolites after excitotoxic injury and global ischemia in neonatal rat brain
10. Imaging of the apparent diffusion coefficient for the evaluation of cerebral metabolic recovery after cardiac arrest
11. Lamotrigine. An update of its pharmacology and therapeutic use in epilepsy
12. Proton T2 relaxation of cerebral metabolites during transient global ischemia in rat brain
13. Magnetic resonance imaging and 31P magnetic resonance spectroscopy for evaluating focal cerebral ischemia
14. Combined oxygen and glucose deprivation in cortical cell culture: Calcium-dependent and calcium-independent mechanisms of neuronal injury
15. The relationship between the apparent diffusion coefficient measured by magnetic resonance imaging, anoxic depolarization, and glutamate efflux during experimental cerebral ischemia
16. The effect of cell membrane water permeability on the apparent diffusion coefficient of water
17. NMR imaging of the apparent diffusion coefficient (ADC) for the evaluation of metabolic suppression and recovery after prolonged cerebral ischemia
18. Diffusion and perfusion MR imaging of cerebral ischemia
19. Current concepts of brain edema. Review of laboratory investigations
20. Effects of hypothermia and lamotrigine on trace-conditioned learning after global cerebral ischemia in rabbits
21. Diffusion-weighted magnetic resonance imaging: Rapid and quantitative detection of focal brain ischemia
22. Reversible focal ischemic injury demonstrated by diffusion-weighted magnetic resonance imaging in rats
23. Early detection of regional cerebral ischemia in cats: Comparison of diffusion- and T2-weighted MRI and spectroscopy
24. Dynamic monitoring of cerebral metabolites during and after transient global ischemia in rats by quantitative proton NMR spectroscopy in vivo
25. Effect of aging on cerebral autoregulation during cardiopulmonary bypass. Association with postoperative cognitive dysfunction
26. High temporal resolution diffusion MRI of global cerebral ischemia and reperfusion
27. Adverse cerebral outcomes after coronary bypass surgery
28. Improved therapeutic window for treatment of histotoxic hypoxia with a free radical spin trap
29. Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanisms of damage and treatment
30. Long-term neurologic outcome after cardiac operation
31. Triggering and execution of neuronal death in brain ischaemia: Two phases of glutamate release by different mechanisms
32. A novel endothelin antagonist, A-127722, attenuates ischemic lesion size in rats with temporary middle cerebral artery occlusion: A diffusion and perfusion MRI study
33. Changes in extracellular acid-base homeostasis in cerebral ischemia
34. + channels: A rational and effective strategy against ischemic brain damage
35. Long-term outcome when major complications follow coronary artery bypass graft surgery. Recovery after complicated coronary artery bypass graft surgery
36. Similar potency of carbamazepine, oxcarbazepine, and lamotrigine in inhibiting the release of glutamate and other neurotransmitters
37. Time-course and treatment response with SNX-111, an N-type calcium channel blocker, in a rodent model of focal cerebral ischemia using diffusion-weighted MRI