Synthesis of actiketal, a glutarimide antibiotic

Tetrahedron Letters

Volumn 41, Issue 31, 2000, Pages 5887-5890

  Kiyota, Hiromasa ^a   Shimizu, Yuko ^a   Oritani, Takayuki ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Acetals; Antibiotics; Glutarimides; Polyketides

Indexed keywords

ACTIKETAL; ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BACTERIUM CULTURE; GROWTH INHIBITION; STREPTOMYCES; SYNTHESIS;

EID: 0034729966     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)00928-X     Document Type: Article

References (13)

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11. 3 failed in decomposition of the product.
12. 1; amorphous powder, mp 79.5-80.5°C (Ref. 1 96-100°C). The mixed melting point could not be measured because the natural sample was absent. However, the value of the synthetic product is reliable for its smaller melting range (Δ 1°C).
13. 5, 290.1029; found, 290.1029.