Use of the bisphosphonate drug alendronate for palliative management of osteosarcoma in two dogs

Veterinary Record

Volumn 147, Issue 5, 2000, Pages 129-132

  Tomlin, J L ^a   Sturgeon, C ^a   Pead, M J ^a   Muir, P ^a,b  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE;

ARTICLE; BONE REMODELING; DOG; DRUG EFFECT; MALE; MAXILLA; NONHUMAN; OSTEOLYSIS; OSTEOSARCOMA; PALLIATIVE THERAPY; TIBIA; VETERINARY MEDICINE;

EID: 0034729913     PISSN: 00424900     EISSN: None     Source Type: Journal    
DOI: 10.1136/vr.147.5.129     Document Type: Article

References (20)

1. ATTARDO-PARRINELLO, G., MERLINI, G., PAVESI, F., CREMA, F., FIORENTINI, M. L. & ASCARI, E. (1987) Effects of a new animodiphosphonate (aminohydroxybutylidene diphosphonate) in patients with osteolytic lesions from metastasis and myelomatosis. Archives of Internal Medicine 147, 1629-1633
2. BERG, J., WEINSTEIN, M. J., SPRINGFIELD, D. S. & RAND, W. M. (1995) Results of surgery and doxorubicin chemotherapy in dogs with osteosarcoma. Journal of the American Veterinary Medical Association 206, 1535-1560
3. BRODEY, R. S. & ABT, D. A. (1976) Results of surgical treatment in 65 dogs with osteosarcoma. Journal of the American Veterinary Medical Association 168, 1032-1035
4. BRODEY, R. S. & RISER, W. H. (1969) Canine osteosarcoma. Clinical Orthopaedics find Related Research 62, 54-64
5. CLOHISY, D. R. & RAMNARAINE, M. L. (1998) Osteoclasts are required for bone tumors to grow and destroy bone. Journal of Orthopaedic Research 16, 660-666
6. DIENER, K. M. (1996) Bisphosphonates for controlling pain from metastatic bone disease. American Journal of Health-System Pharmacy 53, 1917-1927
7. HAMMER, A. S., WEEREN, F. R., WEISBRODE, S. E. & PADGETT, S. L. (1995) Prognostic factors in dogs with osteosarcomas of the flat or irregular bones. Journal of the American Animal Hospital Association 31, 321-326
8. HEYMAN, S. J., DIEFENDERFER, D. L., GOLDSCHMIDT, M. H. & NEWTON, C. D. (1992) Canine axial skeletal osteosarcoma. A retrospective study of 115 cases (1986-1989). Veterinary Surgery 21, 304-310
9. JONGEWARD, S. J. (1985) Primary bone tumours. Veterinary Clinics of North America 15, 609-641
10. KRAEGEL, S. A., MADEWELL, B. R., SIMONSON, E. & GREGORY, C. R. (1991) Osteogenic sarcoma and cisplatin chemotherapy in dogs: 16 cases (1986-1989). Journal of the American Veterinary Medical Association 199, 1057-1059
11. KURZMAN, I. D, MacEWEN, E. G., ROSENTHAL, R. C, FOX, L. E., KELLER, E. T., HELFAND, S. C., VAIL, D. M., DUBIELZIG, R. R., MADEWELL, B. R., RODRIGUEZ, Jr, C. O., OBRADOVICH, J., FIDEL, J. & ROSENBURG, M. (1995) Adjuvant therapy for osteosarcoma in dogs: results of randomized clinical trials using combined liposome-encapsulated muramyl tripeptide and cisplatinum. Clinical Cancer Research 1, 1595-1601
12. LIN, J. H. (1996) Bisphosphonates: a review of their pharmacokinetic properties. Bone 18, 75-85
13. MUNDY G. R. & YONEDA, T. (1998) Bisphosphonates as anticancer drugs. New England Journal of Medicine 339, 398-400
14. PETER, C. P., COOK, W. O., NUNAMAKER, D. M., PROVOST, M. T., SEEDOR, I. G. & RODAN, G. A. (1996) Effect of alendronate on fracture healing and bone remodeling in dogs. Journal of Orthopaedic Research 14, 74-79
15. PIRKEY-EHRHART, N., WITHROW, S. J., STRAW, R. C., EHRHART, E. J., PAGE, R. L., HOTTINGER, H. L., HAHN, K. A., MORRISON, W. B., ALBRECHT, M. R., HEDLUND, C. S., HAMMER A. S., HOLMBERG, D. L., MOORE, A. S., KING, R. R. & KLAUSNER, J. S. (1995) Primary rib tumors in 54 dogs. Journal of the American Animal Hospital Association 31, 65-69
16. RU, G., TERRACINI, B. & GLICKMAN, L. T. (1998) Host related risk factors for canine osteosarcoma. Veterinary Journal 156, 31-39
17. SPODNICK, G. J., BERG, I., RAND, W. M., SCHELLING, S. H., COUTO, G., HARVEY, H. J., HENDERSON, R. A., MacEWEN, G., MAULDIN, N., McCAW, D. L., MOORE, A. S., MORRISON, W., NORRIS, A. M., O'BRADOVICH, I., O'KEEFE, D. A., PAGE, R., RUSLANDER, D., KLAUSNER, J., STRAW, R., THOMPSON, J. P. & WITHROW, S. J. (1992) Prognosis for dogs with appendicular osteosarcoma treated by amputation alone: 162 cases (1978-1988). Journal of the American Veterinary Medical Association 2000, 995-999
18. STRAW, R. C. & WITHROW, S. J. (1996) Limb-sparing surgery versus amputation for dogs with bone tumors. Veterinary Clinics of North America: Small Animal Practice 26, 135-143
19. STRAW, R. C., WITHROW, S. J., RICHTER, S. L., POWERS, B. E., KLEIN, M. K., POSTORINO, N. C., LaRUE, S. M., OGILVIE, G. K., VAIL, D. M., MORRISON, W. B., McGEE, M. & DICKINSON, K. (1991) Amputation and cisplatin for treatment of canine osteosarcoma. Journal of Veterinary Internal Medicine 5, 205-210
20. WITHROW, S. J., POWERS, B. E., STRAW, R. C. & WILKINS, R. M. (1991) Comparative aspects of osteosarcoma. Dog versus man. Clinical Orthopaedics and Related Research 270, 159-168