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Volumn 355, Issue 1397, 2000, Pages 613-622

Identification and analysis of bacterial virulence genes in vivo

Author keywords

Competitive index; Signature tagged mutagenesis; SPI 2; Type III secretion

Indexed keywords

ANIMALIA; BACTERIA (MICROORGANISMS); SALMONELLA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0034729483     PISSN: 09628436     EISSN: None     Source Type: Journal    
DOI: 10.1098/rstb.2000.0602     Document Type: Article
Times cited : (32)

References (54)
  • 1
    • 0025274656 scopus 로고
    • The primary effect of the ity locus is on the rate of growth of Salmonella typhimurium that are relatively protected from killing
    • Benjamin Jr, W. H., Hall, P., Roberts, S. J. & Briles, D. E. 1990 The primary effect of the ity locus is on the rate of growth of Salmonella typhimurium that are relatively protected from killing. J. Immunol. 144, 3143-3151.
    • (1990) J. Immunol. , vol.144 , pp. 3143-3151
    • Benjamin W.H., Jr.1    Hall, P.2    Roberts, S.J.3    Briles, D.E.4
  • 2
    • 0032800559 scopus 로고    scopus 로고
    • pH-dependent secretion of SseB, a product of the SPI-2 type III secretion system of Salmonella typhimurium
    • Beuzon, C. R., Banks, G., Deiwick, J., Hensel, M. & Holden, D. W. 1999 pH-dependent secretion of SseB, a product of the SPI-2 type III secretion system of Salmonella typhimurium. Mol. Microbiol. 33, 806-816.
    • (1999) Mol. Microbiol. , vol.33 , pp. 806-816
    • Beuzon, C.R.1    Banks, G.2    Deiwick, J.3    Hensel, M.4    Holden, D.W.5
  • 3
    • 0033230438 scopus 로고    scopus 로고
    • The tripartite type III secreton of Shigella flexneri inserts IpaB and IpaC into host membranes
    • Blocker, A., Gounon, P., Larquet, E., Niebuhr, K., Cabiaux, V., Parsot, C. & Sansonetti, P. 1999 The tripartite type III secreton of Shigella flexneri inserts IpaB and IpaC into host membranes. J. Cell Biol. 147, 683-693.
    • (1999) J. Cell Biol. , vol.147 , pp. 683-693
    • Blocker, A.1    Gounon, P.2    Larquet, E.3    Niebuhr, K.4    Cabiaux, V.5    Parsot, C.6    Sansonetti, P.7
  • 4
    • 0031869632 scopus 로고    scopus 로고
    • At least four percent of the Salmonella typhimurium genome is required for fatal infection of mice
    • Bowe, F., Lipps, C. J., Tsolis, R. M., Groisman, E., Heffron, F. & Kusters, J. G. 1998 At least four percent of the Salmonella typhimurium genome is required for fatal infection of mice. Infect. Immun. 66, 3372-3377.
    • (1998) Infect. Immun. , vol.66 , pp. 3372-3377
    • Bowe, F.1    Lipps, C.J.2    Tsolis, R.M.3    Groisman, E.4    Heffron, F.5    Kusters, J.G.6
  • 5
    • 0032129785 scopus 로고    scopus 로고
    • Insertional mutagenesis of pathogenic fungi
    • Brown, J. S. & Holden, D. W. 1998 Insertional mutagenesis of pathogenic fungi. Curr. Opin. Microbiol. 1, 390-394.
    • (1998) Curr. Opin. Microbiol. , vol.1 , pp. 390-394
    • Brown, J.S.1    Holden, D.W.2
  • 6
    • 0031953143 scopus 로고    scopus 로고
    • Use of signature-tagged transposon mutagenesis to identify Vibrio cholerae genes critical for colonization
    • Chiang, S. L. & Mekalanos, J. J. 1998 Use of signature-tagged transposon mutagenesis to identify Vibrio cholerae genes critical for colonization. Mol. Microbiol. 27, 797-806.
    • (1998) Mol. Microbiol. , vol.27 , pp. 797-806
    • Chiang, S.L.1    Mekalanos, J.J.2
  • 7
    • 0031717496 scopus 로고    scopus 로고
    • Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival
    • Cirillo, D. M., Valdivia, R. H., Monack, D. M. & Falkow, S. 1998 Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival. Mol. Microbiol. 30, 175-188.
    • (1998) Mol. Microbiol. , vol.30 , pp. 175-188
    • Cirillo, D.M.1    Valdivia, R.H.2    Monack, D.M.3    Falkow, S.4
  • 8
    • 0033597797 scopus 로고    scopus 로고
    • An adhesin of the yeast pathogen Candida glabrata mediating adherence to human epithelial cells
    • Cormack, B. P., Ghori, N. & Falkow, S. 1999 An adhesin of the yeast pathogen Candida glabrata mediating adherence to human epithelial cells. Science 285, 378-582.
    • (1999) Science , vol.285 , pp. 378-582
    • Cormack, B.P.1    Ghori, N.2    Falkow, S.3
  • 10
    • 0013692249 scopus 로고    scopus 로고
    • Salmonella InvG forms a ring-like multimer that requires the InvH lipoprotein for outer membrane localization
    • Crago, A. M. & Koronakis, V. 1998 Salmonella InvG forms a ring-like multimer that requires the InvH lipoprotein for outer membrane localization. Mol. Microbiol. 23, 861-867.
    • (1998) Mol. Microbiol. , vol.23 , pp. 861-867
    • Crago, A.M.1    Koronakis, V.2
  • 11
    • 0032911032 scopus 로고    scopus 로고
    • Identification of Yersinia enterocolitica genes affecting survival in an animal host using signature-tagged transposon mutagenesis
    • Darwin, A. J. & Miller, V. L. 1999 Identification of Yersinia enterocolitica genes affecting survival in an animal host using signature-tagged transposon mutagenesis. Mol. Microbiol. 32, 51-62.
    • (1999) Mol. Microbiol. , vol.32 , pp. 51-62
    • Darwin, A.J.1    Miller, V.L.2
  • 12
    • 0033064188 scopus 로고    scopus 로고
    • Environmental regulation of Salmonella pathogenicity island 2 gene expression
    • Deiwick, J., Niklaus, T., Erdogan, S. & Hensel, M. 1999 Environmental regulation of Salmonella pathogenicity island 2 gene expression. Mol. Microbiol. 31, 1759-1773.
    • (1999) Mol. Microbiol. , vol.31 , pp. 1759-1773
    • Deiwick, J.1    Niklaus, T.2    Erdogan, S.3    Hensel, M.4
  • 13
    • 0028358260 scopus 로고
    • Analysis and construction of stable phenotypes in Gram-negative bacteria with Tn5- and Tn10-derived minitransposons
    • de Lorenzo, V. & Timmis, K. N. 1994 Analysis and construction of stable phenotypes in Gram-negative bacteria with Tn5- and Tn10-derived minitransposons. Meth. Enzymol. 235, 386-405.
    • (1994) Meth. Enzymol. , vol.235 , pp. 386-405
    • De Lorenzo, V.1    Timmis, K.N.2
  • 14
    • 0032167951 scopus 로고    scopus 로고
    • Interdependence of mycobacterial iron regulation, oxidative-stress response and isoniazid resistance
    • Dussurget, O. & Smith, I. 1998 Interdependence of mycobacterial iron regulation, oxidative-stress response and isoniazid resistance. Trends Microbiol. 6, 354-358.
    • (1998) Trends Microbiol. , vol.6 , pp. 354-358
    • Dussurget, O.1    Smith, I.2
  • 15
    • 0031696843 scopus 로고    scopus 로고
    • Initial binding of Shiga toxin-producing Escherichia coli to host cells and subsequent induction of actin rearrangements depend on filamentous EspA-containing surface appendages
    • Ebel, F., Podzadel, T., Rohde, M., Kresse, A. U., Kramer, S., Deibel, C., Guzḿn, C. A. & Chakraborty, T. 1998 Initial binding of Shiga toxin-producing Escherichia coli to host cells and subsequent induction of actin rearrangements depend on filamentous EspA-containing surface appendages. Mol. Microbiol. 30, 147-161.
    • (1998) Mol. Microbiol. , vol.30 , pp. 147-161
    • Ebel, F.1    Podzadel, T.2    Rohde, M.3    Kresse, A.U.4    Kramer, S.5    Deibel, C.6    Guzḿn, C.A.7    Chakraborty, T.8
  • 16
    • 0033529245 scopus 로고    scopus 로고
    • Discovery of virulence genes of Legionella pneumophila by using signature-tagged mutagenesis in a guinea pig pneumonia model
    • Edelstein, P. H., Edelstein, M. A. C., Higa, F. & Falkow, S. 1999 Discovery of virulence genes of Legionella pneumophila by using signature-tagged mutagenesis in a guinea pig pneumonia model. Proc. Natl Acad. Sci. USA 96, 8190-8195.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 8190-8195
    • Edelstein, P.H.1    Edelstein, M.A.C.2    Higa, F.3    Falkow, S.4
  • 19
    • 0026720513 scopus 로고
    • Molecular and functional characterisation of the Salmonella invasion gene invA: Homology of InvA to members of a new protein family
    • Galan, J. E., Ginocchio, C. & Costeas, P. 1992 Molecular and functional characterisation of the Salmonella invasion gene invA: homology of InvA to members of a new protein family. J. Bacteriol. 174, 4338-4349.
    • (1992) J. Bacteriol. , vol.174 , pp. 4338-4349
    • Galan, J.E.1    Ginocchio, C.2    Costeas, P.3
  • 20
    • 0029671310 scopus 로고    scopus 로고
    • 2+ as an extracellular signal: Environmental regulation of Salmonella virulence
    • 2+ as an extracellular signal: environmental regulation of Salmonella virulence. Cell 84, 165-174.
    • (1996) Cell , vol.84 , pp. 165-174
    • Garcia Vescovi, E.1    Soncini, F.C.2    Groisman, E.A.3
  • 21
    • 0028859357 scopus 로고
    • Adhesion properties of mutants of Staphylococcus aureus defective in fibronectin-binding proteins and studies on the expression of fnb genes
    • Greene, C., McDevitt, D., Francois, P., Vaudaux, P. E., Lew, D. P. & Foster, T. J. 1995 Adhesion properties of mutants of Staphylococcus aureus defective in fibronectin-binding proteins and studies on the expression of fnb genes. Mol. Microbiol. 17, 1143-1152.
    • (1995) Mol. Microbiol. , vol.17 , pp. 1143-1152
    • Greene, C.1    McDevitt, D.2    Francois, P.3    Vaudaux, P.E.4    Lew, D.P.5    Foster, T.J.6
  • 22
    • 0030870440 scopus 로고
    • How Salmonella became a pathogen
    • Groisman, E. A. & Ochman, H. 1994 How Salmonella became a pathogen. Trends Microbiol. 5, 343-349.
    • (1994) Trends Microbiol. , vol.5 , pp. 343-349
    • Groisman, E.A.1    Ochman, H.2
  • 23
    • 0027395895 scopus 로고
    • The Salmonella typhimurium virulence plasmid increases the growth rate of salmonellae in mice
    • Gulig, P. A. & Doyle, T. J. 1993 The Salmonella typhimurium virulence plasmid increases the growth rate of salmonellae in mice. Infect. Immun. 61, 504-511.
    • (1993) Infect. Immun. , vol.61 , pp. 504-511
    • Gulig, P.A.1    Doyle, T.J.2
  • 24
    • 0029117137 scopus 로고
    • Simultaneous identification of bacterial virulence genes by negative selection
    • Hensel, M., Shea, J. E., Gleeson, C., Jones, M. D., Dalton, E. & Holden, D. W. 1995 Simultaneous identification of bacterial virulence genes by negative selection. Science 269, 400-403.
    • (1995) Science , vol.269 , pp. 400-403
    • Hensel, M.1    Shea, J.E.2    Gleeson, C.3    Jones, M.D.4    Dalton, E.5    Holden, D.W.6
  • 25
    • 0031053290 scopus 로고    scopus 로고
    • Analysis of the boundaries of Salmonella pathogenicity island 2 and the corresponding chromosomal region of Escherichia coli K-12
    • Hensel, M., Shea, J. E., Bäumler, A. J., Gleeson, C., Blattner, F. & Holden, D. W. 1997a Analysis of the boundaries of Salmonella pathogenicity island 2 and the corresponding chromosomal region of Escherichia coli K-12. J. Bacteriol. 179, 1105-1111.
    • (1997) J. Bacteriol. , vol.179 , pp. 1105-1111
    • Hensel, M.1    Shea, J.E.2    Bäumler, A.J.3    Gleeson, C.4    Blattner, F.5    Holden, D.W.6
  • 26
    • 0030941952 scopus 로고    scopus 로고
    • Functional analysis of ssaJ and the ssaK/U operon, thirteen genes encoding components of the type III secretion apparatus of Salmonella pathogenicity island 2
    • Hensel, M., Shea, J. E., Raupach, B., Monack, D., Falkow, S., Gleeson, C., Kubo, T. & Holden, D. W. 1997b Functional analysis of ssaJ and the ssaK/U operon, thirteen genes encoding components of the type III secretion apparatus of Salmonella pathogenicity island 2. Mol. Microbiol. 24, 155-167.
    • (1997) Mol. Microbiol. , vol.24 , pp. 155-167
    • Hensel, M.1    Shea, J.E.2    Raupach, B.3    Monack, D.4    Falkow, S.5    Gleeson, C.6    Kubo, T.7    Holden, D.W.8
  • 27
    • 14444287535 scopus 로고    scopus 로고
    • Genes encoding putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation in macrophages
    • Hensel, M., Shea, J. E., Waterman, S. R., Mundy, R., Nikolaus, T., Banks, G., Vasquez-Torres, A., Gleeson, C., Fang, F. C. & Holden, D. W. 1998 Genes encoding putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation in macrophages. Mol. Microbiol. 30, 163-174.
    • (1998) Mol. Microbiol. , vol.30 , pp. 163-174
    • Hensel, M.1    Shea, J.E.2    Waterman, S.R.3    Mundy, R.4    Nikolaus, T.5    Banks, G.6    Vasquez-Torres, A.7    Gleeson, C.8    Fang, F.C.9    Holden, D.W.10
  • 28
    • 0032923401 scopus 로고    scopus 로고
    • The genetic basis of tetrathionate respiration in Salmonella typhimurium
    • Hensel, M., Hinsley, A. P., Nikolaus, T., Sawers, G. & Berks, B. C. 1999 The genetic basis of tetrathionate respiration in Salmonella typhimurium. Mol. Microbiol. 32, 275-287.
    • (1999) Mol. Microbiol. , vol.32 , pp. 275-287
    • Hensel, M.1    Hinsley, A.P.2    Nikolaus, T.3    Sawers, G.4    Berks, B.C.5
  • 29
    • 0031864184 scopus 로고    scopus 로고
    • Type III protein secretion systems in bacterial pathogens of animals and plants
    • Hueck, C. J. 1998 Type III protein secretion systems in bacterial pathogens of animals and plants. Microbiol. Mol. Biol. Rev. 62, 379-433.
    • (1998) Microbiol. Mol. Biol. Rev. , vol.62 , pp. 379-433
    • Hueck, C.J.1
  • 30
    • 0027982037 scopus 로고
    • The Salmonella typhimurium invasion genes invF and invG encode homologs of the AraC and PulD family of proteins
    • Kaniga, K., Bossio, J. C. & Galan, J. E. 1994 The Salmonella typhimurium invasion genes invF and invG encode homologs of the AraC and PulD family of proteins. Mol. Microbiol. 13, 555-568.
    • (1994) Mol. Microbiol. , vol.13 , pp. 555-568
    • Kaniga, K.1    Bossio, J.C.2    Galan, J.E.3
  • 31
    • 0032522344 scopus 로고    scopus 로고
    • A novel EspA-associated surface organelle of enteropathogenic Escherichia coli involved in protein translocation into epithelial cells
    • Knutton, S., Rosenshine, I., Pallen, M. J., Nisan, I., Neves, B. C., Bain, C., Wolff, C., Dougan, G. & Frankel, G. 1998 A novel EspA-associated surface organelle of enteropathogenic Escherichia coli involved in protein translocation into epithelial cells. EMBO J. 17, 2166-2176.
    • (1998) EMBO J. , vol.17 , pp. 2166-2176
    • Knutton, S.1    Rosenshine, I.2    Pallen, M.J.3    Nisan, I.4    Neves, B.C.5    Bain, C.6    Wolff, C.7    Dougan, G.8    Frankel, G.9
  • 32
    • 0031780325 scopus 로고    scopus 로고
    • Identification of novel staphylococcal virulence genes by in vivo expression technology
    • Lowe, A. M., Beattie, D. T. & Deresiewicz, R. L. 1998 Identification of novel staphylococcal virulence genes by in vivo expression technology. Mol. Microbiol. 27, 967-976.
    • (1998) Mol. Microbiol. , vol.27 , pp. 967-976
    • Lowe, A.M.1    Beattie, D.T.2    Deresiewicz, R.L.3
  • 33
    • 0032551901 scopus 로고    scopus 로고
    • Staphylococcus aureus infections
    • Lowy, F. D. 1998 Staphylococcus aureus infections. N. Engl. J. Med. 339, 520-532.
    • (1998) N. Engl. J. Med. , vol.339 , pp. 520-532
    • Lowy, F.D.1
  • 34
    • 0027497926 scopus 로고
    • Selection of bacterial virulence genes that are specifically induced in host tissues
    • Mahan, M. J., Slauch, J. M. & Mekalanos, J. J. 1993 Selection of bacterial virulence genes that are specifically induced in host tissues. Science 259, 686-688.
    • (1993) Science , vol.259 , pp. 686-688
    • Mahan, M.J.1    Slauch, J.M.2    Mekalanos, J.J.3
  • 35
    • 0030609131 scopus 로고    scopus 로고
    • Identification of Staphylococcus aureus virulence genes in a murine model of bacteremia using signature-tagged mutagenesis
    • Mei, J.-M., Nourbakhsh, F., Ford, C. W. & Holden, D. W. 1997 Identification of Staphylococcus aureus virulence genes in a murine model of bacteremia using signature-tagged mutagenesis. Mol. Microbiol. 26, 399-407.
    • (1997) Mol. Microbiol. , vol.26 , pp. 399-407
    • Mei, J.-M.1    Nourbakhsh, F.2    Ford, C.W.3    Holden, D.W.4
  • 36
    • 0024316290 scopus 로고
    • Isolation of orally attenuated Salmonella typhimurium following TnphoA mutagenesis
    • Miller, I., Maskell, D., Hormaeche, C., Johnson, K., Pickard, D. & Dougan, G. 1989 Isolation of orally attenuated Salmonella typhimurium following TnphoA mutagenesis. Infect. Immun. 57, 2758-2763.
    • (1989) Infect. Immun. , vol.57 , pp. 2758-2763
    • Miller, I.1    Maskell, D.2    Hormaeche, C.3    Johnson, K.4    Pickard, D.5    Dougan, G.6
  • 37
    • 0032835828 scopus 로고    scopus 로고
    • Insertion of a Yop translocation pore into the macrophage plasma membrane by Yersinia enterocolitica: Requirement for translocators YopB and YopD, but not LcrG
    • Neyt, C. & Cornells, G. R. 1999 Insertion of a Yop translocation pore into the macrophage plasma membrane by Yersinia enterocolitica: requirement for translocators YopB and YopD, but not LcrG. Mol. Microbiol. 33, 971-981.
    • (1999) Mol. Microbiol. , vol.33 , pp. 971-981
    • Neyt, C.1    Cornells, G.R.2
  • 38
    • 0029852315 scopus 로고    scopus 로고
    • Distribution of pathogenicity islands in Salmonella spp
    • Ochman, H. & Groisman, E. A. 1996 Distribution of pathogenicity islands in Salmonella spp. Inject. Immum. 64, 5410-5412.
    • (1996) Inject. Immum. , vol.64 , pp. 5410-5412
    • Ochman, H.1    Groisman, E.A.2
  • 39
    • 0029817221 scopus 로고    scopus 로고
    • Identification of a pathogenicity island required for Salmonella survival in host cells
    • Ochman, H., Soncini, F. C., Solomon, F. & Groisman, E. A. 1996 Identification of a pathogenicity island required for Salmonella survival in host cells. Proc. Natl Acad. Sci. USA 93, 7800-7804.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 7800-7804
    • Ochman, H.1    Soncini, F.C.2    Solomon, F.3    Groisman, E.A.4
  • 41
    • 0029994912 scopus 로고    scopus 로고
    • Acidification of phagosomes containing Salmonella typhimurium in murine macrophages
    • Rathman, M., Sjaastad, M. D. & Falkow, S. 1996 Acidification of phagosomes containing Salmonella typhimurium in murine macrophages. Infect. Immun. 64, 2765-2773.
    • (1996) Infect. Immun. , vol.64 , pp. 2765-2773
    • Rathman, M.1    Sjaastad, M.D.2    Falkow, S.3
  • 42
    • 0030911922 scopus 로고    scopus 로고
    • The unique trafficking pattern of Salmonella typhimurium-containing phagosomes in murine macrophages is independent of the mechanism of bacterial entry
    • Rathman, M., Barker, L. P. & Falkow, S. 1997 The unique trafficking pattern of Salmonella typhimurium-containing phagosomes in murine macrophages is independent of the mechanism of bacterial entry. Infect. Immun. 65, 1475-1485.
    • (1997) Infect. Immun. , vol.65 , pp. 1475-1485
    • Rathman, M.1    Barker, L.P.2    Falkow, S.3
  • 43
    • 0030807629 scopus 로고    scopus 로고
    • Murine salmonellosis studied by confocal microscopy: Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo
    • Richter-Dahlfors, A., Buchan, A. M. J. & Finlay, B. B. 1997 Murine salmonellosis studied by confocal microscopy: Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo. J. Exp. Med. 184, 569-580.
    • (1997) J. Exp. Med. , vol.184 , pp. 569-580
    • Richter-Dahlfors, A.1    Buchan, A.M.J.2    Finlay, B.B.3
  • 45
    • 0029913901 scopus 로고    scopus 로고
    • Identification of a virulence locus encoding a second type III secretion system in Salmonella typhimurium
    • Shea, J. E., Hensel, M., Gleeson, C. & Holden, D. W. 1996 Identification of a virulence locus encoding a second type III secretion system in Salmonella typhimurium. Proc. Natl Acad. Sci. USA 93, 2593-2597.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 2593-2597
    • Shea, J.E.1    Hensel, M.2    Gleeson, C.3    Holden, D.W.4
  • 46
    • 0032940468 scopus 로고    scopus 로고
    • Influence of the Salmonella typhimurium pathogenicity island 2 type III secretion system on bacterial growth in the mouse
    • Shea, J. E., Beuzon, C. R., Gleeson, C., Mundy, R. & Holden, D. W. 1999 Influence of the Salmonella typhimurium pathogenicity island 2 type III secretion system on bacterial growth in the mouse. Infect. Immun. 67, 213-219.
    • (1999) Infect. Immun. , vol.67 , pp. 213-219
    • Shea, J.E.1    Beuzon, C.R.2    Gleeson, C.3    Mundy, R.4    Holden, D.W.5
  • 47
    • 0028073624 scopus 로고
    • Virulence of Aspergillus fumigatus double mutants lacking restrictocin and an alkaline protease in a low-dose model of invasive pulmonary aspergillosis
    • Smith, J. M., Tang, C. M., Van Noorden, S. & Holden, D.W. 1994 Virulence of Aspergillus fumigatus double mutants lacking restrictocin and an alkaline protease in a low-dose model of invasive pulmonary aspergillosis. Infect. Immun. 62, 5247-5254.
    • (1994) Infect. Immun. , vol.62 , pp. 5247-5254
    • Smith, J.M.1    Tang, C.M.2    Van Noorden, S.3    Holden, D.W.4
  • 48
    • 0032851238 scopus 로고    scopus 로고
    • Pathogen virulence genes - Implications for vaccines and drug therapy
    • Tang, C. & Holden, D. W. 1999 Pathogen virulence genes - implications for vaccines and drug therapy. Br. Med. Bull. 55, 387-400.
    • (1999) Br. Med. Bull. , vol.55 , pp. 387-400
    • Tang, C.1    Holden, D.W.2
  • 49
    • 0345593392 scopus 로고    scopus 로고
    • IpaC induces actin polymerisation and filopodia formation during Shigella entry into epithelial cells
    • Tran Van Nhieu, G., Garon, E., Hall, A. & Sansonetti, P. 1999 IpaC induces actin polymerisation and filopodia formation during Shigella entry into epithelial cells. EMBO J. 18, 3249-3262.
    • (1999) EMBO J. , vol.18 , pp. 3249-3262
    • Tran Van Nhieu, G.1    Garon, E.2    Hall, A.3    Sansonetti, P.4
  • 50
    • 0032795036 scopus 로고    scopus 로고
    • Contribution of Salmonella typhimurium virulence factors to diarrheal disease in calves
    • Tsolis, R. M., Adams, L. G., Ficht, T. A. & Bäumler, A. J. 1999 Contribution of Salmonella typhimurium virulence factors to diarrheal disease in calves. Infect. Immun. 67, 4879-4885.
    • (1999) Infect. Immun. , vol.67 , pp. 4879-4885
    • Tsolis, R.M.1    Adams, L.G.2    Ficht, T.A.3    Bäumler, A.J.4
  • 52
    • 0030866940 scopus 로고    scopus 로고
    • Fluorescence-based isolation of bacterial genes expressed within host cells
    • Valdivia, R. H. & Falkow, S. 1997 Fluorescence-based isolation of bacterial genes expressed within host cells. Science 277, 2007-2011.
    • (1997) Science , vol.277 , pp. 2007-2011
    • Valdivia, R.H.1    Falkow, S.2
  • 53
    • 0028292926 scopus 로고
    • YscN, the putative energiser of the Yersinia Yop secretion machinery
    • Woestyn, S., Allaoui, A., Wattiau, P. & Cornelis, G. R. 1994 YscN, the putative energiser of the Yersinia Yop secretion machinery. J. Bacteriol. 176, 1561-1569.
    • (1994) J. Bacteriol. , vol.176 , pp. 1561-1569
    • Woestyn, S.1    Allaoui, A.2    Wattiau, P.3    Cornelis, G.R.4
  • 54
    • 0032897759 scopus 로고    scopus 로고
    • Identification of protease and rpoN-associated genes of uropathogenic Proteus mirabilis by negative selection in a mouse model of ascending urinary tract infection
    • Zhao, H., Li, X., Johnson, D. E. & Mobley, H. L. 1999 Identification of protease and rpoN-associated genes of uropathogenic Proteus mirabilis by negative selection in a mouse model of ascending urinary tract infection. Microbiology 145, 185-195.
    • (1999) Microbiology , vol.145 , pp. 185-195
    • Zhao, H.1    Li, X.2    Johnson, D.E.3    Mobley, H.L.4


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