Preparation of functionalized alkenylmagnesium bromides via a bromine- magnesium exchange

Tetrahedron Letters

Volumn 41, Issue 18, 2000, Pages 3319-3322

  Thibonnet, Jérôme ^a   Knochel, Paul ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Functionalized organometallics; Magnesium; Nitrile; Sulfone

Indexed keywords

BROMINE; FUNCTIONAL GROUP; MAGNESIUM DERIVATIVE; NITRILE; ORGANOMETALLIC COMPOUND; SULFONE;

ARTICLE; METHODOLOGY; REACTION ANALYSIS; SYNTHESIS;

EID: 0034728944     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)00387-7     Document Type: Article

References (17)

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17. 3SiCl (294 μL, 2.32 mmol) was added and the reaction mixture was allowed to warm to rt and was stirred for 1 h. After the usual work up, the crude residue obtained after evaporation of the solvents was purified by flash-chromatography (pentane:ether, 95:5) yielding the sulfone 9b (401 mg, 82% yield) as a white solid (mp=82°C).