Evaluation of dipeptide α-keto-β-aldehydes as new inhibitors of cathepsin S

Biochemical and Biophysical Research Communications

Volumn 275, Issue 2, 2000, Pages 401-405

  Walker, Brian ^a   Lynas, John F ^a   Meighan, Mark A ^a   Brömme, Dieter ^b  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Cathepsins; Cysteine protease; Glyoxals; Lysosomal enzymes; Peptide based inhibitors; Synthetic inhibitor; Transition state analogues; keto aldehyde

Indexed keywords

CATHEPSIN B; CATHEPSIN S; DIPEPTIDE; ENZYME INHIBITOR; GLYOXAL DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; ENZYME INHIBITION; KINETICS; PRIORITY JOURNAL; REACTION ANALYSIS; STRUCTURE ANALYSIS; SYNTHESIS;

EID: 0034726744     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.3311     Document Type: Article

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