Sorting polyclonal antibodies into functionally distinct fractions using peptide phage display: 'A library on top of a library'

Journal of Immunological Methods

Volumn 242, Issue 1-2, 2000, Pages 183-191

  Moshitch Moshkovitz, S ^a   Heldman, Y ^a   Yayon, A ^a   Katchalski Katzir, E ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Epitope library; Fibroblast growth factor receptor; Peptide phage display; Polyclonal antibodies

Indexed keywords

FIBROBLAST GROWTH FACTOR 1; GROWTH FACTOR RECEPTOR; PEPTIDE; PEPTIDE LIBRARY; POLYCLONAL ANTIBODY;

ARTICLE; CELL LINE; PEPTIDE MAPPING; PEPTIDE SYNTHESIS; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN TARGETING;

AMINO ACID SEQUENCE; ANIMAL; ANTIBODIES; CELL LINE; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, AFFINITY; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PEPTIDES; RABBITS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, FIBROBLAST GROWTH FACTOR; SUPPORT, NON-U.S. GOV'T;

EID: 0034726415     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(00)00247-7     Document Type: Article

References (33)

1. Ballinger M.D., Wells J.A. Will any dimer do? Nat. Struct. Biol. 5:1998;938. news; comment.
2. Basilico C., Moscatelli D. The FGF family of growth factors and oncogenes. Adv. Cancer Res. 59:1992;115.
3. Cortese R., Monaci P., Nicosia A., Luzzago A., Felici F., Galfre G., et al. Identification of biologically active peptides using random libraries displayed on phage. Curr. Opin. Biotechnol. 6:1995;73.
4. Cwirla S.E., Balasubramanian P., Duffin D.J., Wagstrom C.R., Gates C.M., Singer S.C., et al. Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine. Science. 276:1997;1696.
5. De Moerlooze L., Dickson C. Skeletal disorders associated with fibroblast growth factor receptor mutations. Curr. Opin. Genet. Dev. 7:1997;378.
6. Dente L., Vetriani C., Zucconi A., Pelicci G., Lanfrancone L., Pelicci P.G., et al. Modified phage peptide libraries as a tool to study specificity of phosphorylation and recognition of tyrosine containing peptides. J. Mol. Biol. 269:1997;694.
7. Devlin J.J., Panganiban L.C., Devlin P.E. Random peptide libraries: a source of specific protein binding molecules. Science. 249:1990;404.
8. Elliott S., Lorenzini T., Yanagihara D., Chang D., Elliott G. Activation of the erythropoietin (EPO) receptor by bivalent anti-EPO receptor antibodies. J. Biol. Chem. 271:1996;24691.
9. Givol D., Yayon A. Complexity of FGF receptors: genetic basis for structural diversity and functional specificity. Faseb J. 6:1992;3362.
10. Isacchi A., Bergonzoni L., Sarmientos P. Complete sequence of a human receptor for acidic and basic fibroblast growth factors. Nucleic Acids Res. 18:1990;1906.
11. Jaye M., Schlessinger J., Dionne C.A. Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction. Biochim. Biophys. Acta. 1135:1992;185.
12. Johnson D.E., Williams L.T. Structural and functional diversity in the FGF receptor multigene family. Adv. Cancer Res. 60:1993;1.
13. Johnson D.L., Farrell F.X., Barbone F.P., McMahon F.J., Tullai J., Kroon D., et al. Amino-terminal dimerization of an erythropoietin mimetic peptide results in increased erythropoietic activity. Chem. Biol. 4:1997;939.
14. Katz B.A. Binding to protein targets of peptidic leads discovered by phage display: crystal structures of streptavidin-bound linear and cyclic peptide ligands containing the HPQ sequence. Biochemistry. 34:1995;15421.
15. Klint P., Claesson-Welsh L. Signal transduction by fibroblast growth factor receptors. Front Biosci. 4:1999;D165.
16. Lee P.L., Johnson D.E., Cousens L.S., Fried V.A., Williams L.T. Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor. Science. 245:1989;57.
17. Li M., Bernard O. FDC-P1 myeloid cells engineered to express fibroblast growth factor receptor 1 proliferate and differentiate in the presence of fibroblast growth factor and heparin. Proc. Natl. Acad. Sci. USA. 89:1992;3315.
18. Mason I.J. The ins and outs of fibroblast growth factors. Cell. 78:1994;547.
19. Merrifield R.B., Merrifield E.L., Juvvadi P., Andreu D., Boman H.G. Design and synthesis of antimicrobial peptides. Ciba Found. Symp. 186:1994;5.
20. Muenke M., Schell U. Fibroblast-growth-factor receptor mutations in human skeletal disorders. Trends Genet. 11:1995;308.
21. Neilson K.M., Friesel R. Ligand-independent activation of fibroblast growth factor receptors by point mutations in the extracellular, transmembrane, and kinase domains. J. Biol. Chem. 271:1996;25049.
22. Ornitz D.M., Yayon A., Flanagan J.G., Svahn C.M., Levi E., Leder P. Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells. Mol. Cell. Biol. 12:1992;240.
23. Parmley S.F., Smith G.P. Filamentous fusion phage cloning vectors for the study of epitopes and design of vaccines. Adv. Exp. Med. Biol. 251:1989;215.
24. Plotnikov A.N., Schlessinger J., Hubbard S.R., Mohammadi M. Structural basis for FGF receptor dimerization and activation. Cell. 98:1999;641.
25. Ruta M., Burgess W., Givol D., Epstein J., Neiger N., Kaplow J., et al. Receptor for acidic fibroblast growth factor is related to the tyrosine kinase encoded by the fms-like gene (FLG). Proc. Natl. Acad. Sci. USA. 86:1989;8722.
26. Scott J.K., Smith G.P. Searching for peptide ligands with an epitope library. Science. 249:1990;386.
27. Spooncer E., Katsuno M., Hampson I., Dexter T.M., Just U., Stocking C., et al. Biological effects of retroviral transfection of the murine interleukin- 3 gene into FDCP-Mix cells. Curr. Top. Microbiol. Immunol. 149:1989;109.
28. Stauber D.J., DiGabriele A.D., Hendrickson W.A. Structural interactions of fibroblast growth factor receptor with its ligands. Proc. Natl. Acad. Sci. USA. 97:2000;49. In process citation.
29. Webster M.K., Donoghue D.J. FGFR activation in skeletal disorders: too much of a good thing. Trends Genet. 13:1997;178.
30. Wrighton N.C., Balasubramanian P., Barbone F.P., Kashyap A.K., Farrell F.X., Jolliffe L.K., et al. Increased potency of an erythropoietin peptide mimetic through covalent dimerization. Nat. Biotechnol. 15:1997;1261.
31. Wrighton N.C., Farrell F.X., Chang R., Kashyap A.K., Barbone F.P., Mulcahy L.S., et al. Small peptides as potent mimetics of the protein hormone erythropoietin. Science. 273:1996;458.
32. Yayon A., Aviezer D., Safran M., Gross J.L., Heldman Y., Cabilly S., et al. Isolation of peptides that inhibit binding of basic fibroblast growth factor to its receptor from a random phage-epitope library. Proc. Natl. Acad. Sci. USA. 90:1993;10643.
33. Yayon A., Zimmer Y., Shen G.H., Avivi A., Yarden Y., Givol D. A confined variable region confers ligand specificity on fibroblast growth factor receptors: implications for the origin of the immunoglobulin fold. Embo J. 11:1992;1885.