Immobility accompanies the antinociception mediated by the rostral ventromedial medulla of the rat

Brain Research

Volumn 872, Issue 1-2, 2000, Pages 276-281

  Morgan, Michael M ^a   Whitney, Pamela K ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Pain modulation: anatomy and physiology

Indexed keywords

KAINIC ACID; MORPHINE;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; LOCOMOTION; MALE; MEDULLA OBLONGATA; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT;

EID: 0034725768     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02502-6     Document Type: Article

References (53)

1. R. Bandler M.T. Shipley Columnar organization in the midbrain periaqueductal gray: modules for emotional expression? Trends Neurosci. 17 1994 379 389
2. A.I. Basbaum H.L. Fields Endogenous pain control systems: Brainstem spinal pathways and endorphin circuitry Ann. Rev. Neurosci. 7 1984 309 338
3. M.M. Behbehani H.L. Fields Evidence that an excitatory connection between the periaqueductal gray and nucleus raphe magnus mediates stimulation produced analgesia Brain Res. 170 1979 85 93
4. A.J. Beitz M.A. Mullett L.I. Weiner The periaqueductal gray projections to the rat spinal trigeminal, raphe magnus, gigantocellular pars alpha and paragigantocellular nuclei arise from separate neurons Brain Res. 288 1983 307 314
5. R.C. Bolles Species-specific defense reactions and avoidance learning Psychol. Rev. 77 1970 32 48
6. J.T. Cannon G.J. Prieto A. Lee J.C. Liebeskind Evidence for opioid and nonopioid forms of stimulation-produced analgesia in the rat Brain Res. 243 1982 315 321
7. P. Carrive Functional organization of midbrain periaqueductal grey neurons controlling regional vascular beds A. Depaulis R. Bandler The Midbrain Periaqueductal Gray Matter 1991 Plenum London 67 100
8. P. Carrive Conditioned fear to environmental context: Cardiovascular and behavioral components in the rat Brain Res. 858 2000 440 445
9. P. Carrive R. Bandler R.A.L. Dampney Viscerotopic control of regional vascular beds by discrete groups of neurons within the midbrain periaqueductal gray Brain Res. 493 1989 385 390
10. P. Carrive R.A.L. Dampney R. Bandler Excitation of neurones in restricted portion of the midbrain periaqueductal grey matter elicits both behavioural and cardiovascular components of the defence reaction in the unanaesthetised decerebrate cat Neurosci. Lett. 81 1987 273 278
11. P. Carrive P. Leung J. Harris G. Paxinos Conditioned fear to context is associated with increased Fos expresssion in the caudal ventrolateral region of the midbrain periaqueductal gray Neurosci. 78 1997 165 177
12. B.M. De Oca J.P. DeCola S. Maren M.J. Fanselow Distinct regions of the periaqueductal gray are involved in the acquisition and expression of defensive responses J. Neurosci. 18 1998 3426 3432
13. A.H. Dickenson J.-L. Oliveras J.-M. Besson Role of the nucleus raphe manus in opiate analgesia as studied by the microinjection technique in the rat Brain Res. 170 1979 95 111
14. M.S. Fanselow Conditioned and unconditional components of post-shock freezing Pav. J. Biol. Sci. 15 1980 177 182
15. M.S. Fanselow The midbrain periaqueductal gray as a coordinator of action in response to fear and anxiety A. Depaulis R. Bandler The Midbrain Periaqueductal Gray Matter Vol. 213 1991 Plenum Press New York 151 173
16. V. Fardin J.L. Oliveras J.M. Besson Projections from the periaqueductal gray matter to the B3 cellular area (nucleus raphe magnus and nucleus reticularis paragigantocellularis) as revealed by the retrograde transport of horseradish peroxidase in the rat J. Comp. Neurol. 223 1984 483 500
17. V. Fardin J.L. Oliveras J.M. Besson A reinvestigation of the analgesic effects induced by stimulation of the periaqueductal gray matter in the rat. II. Differential characteristics of the analgesia induced by ventral and dorsal PAG stimulation Brain Res. 306 1984 125 139
18. H.L. Fields A.I. Basbaum C.H. Clanton S.D. Anderson Nucleus raphe magnus inhibition of spinal cord dorsal horn neurons Brain Res. 126 1977 441 453
19. H.L. Fields M.M. Heinricher P. Mason Neurotransmitters in nociceptive modulatory circuits Ann. Rev. Neurosci. 14 1991 219 245
20. H.L. Fields A. Malick R. Burstein Dorsal horn projection targets of ON and OFF cells in the rostral ventromedial medulla J. Neurophysiol. 74 1995 1742 1759
21. H. Foo F.J. Helmstetter Hypoalgesia elicited by a conditioned stimulus is blocked by a mu, but not a delta or a kappa, opioid antagonist injected into the rostral ventromedial medulla Pain 83 1999 427 431
22. M.M. Heinricher C.M. Haws H.L. Fields Evidence for GABA-mediated control of putative nociceptive modulating neurons in the rostral ventromedial medulla: Iontophoresis of bicuculline eliminates the off-cell pause Somatosen. Motor Res. 8 1991 215 225
23. M.M. Heinricher H.J. Kaplan GABA-mediated inhibition in rostral ventromedial medulla: role in nociceptive modulation in the lightly anesthetized rat Pain 47 1991 105 113
24. M.M. Heinricher M.M. Morgan H.L. Fields Direct and indirect actions of morphine on medullary neurons that modulate nociception Neuroscience 48 1992 533 543
25. M.M. Heinricher M.M. Morgan V. Tortorici H.L. Fields Disinhibition of off-cells and antinociception produced by an opioid action within the rostral ventromedial medulla Neuroscience 63 1994 279 288
26. F.J. Helmstetter S.A. Tershner Lesions of the periaqueductal gray and rostral ventromedial medulla disrupt antinociceptive but not cardiovascular aversive conditional responses J. Neurosci. 14 1994 7099 7108
27. Y.F. Jacquet A. Lajtha Paradoxical effects after microinjection of morphine in the periaqueductal gray matter in the rat Science 185 1974 1055 1057
28. T.S. Jensen T.L. Yaksh I. Comparison of antinociceptive action of morphine in the periaqueductal gray, medial and paramedial medulla in rat Brain Res. 363 1986 99 113
29. T.S. Jensen T.L. Yaksh Comparison of the antinociceptive effect of morphine and glutamate at coincidental sites in the periaqueductal gray and medial medulla in rats Brain Res. 476 1989 1 9
30. K.A. Keay R. Bandler Deep and superficial noxious stimulation increases Fos-like immunoreactivity in different regions of the midbrain periaqueductal grey of the rat Neurosci. Lett. 154 1993 23 26
31. K.A. Keay C.I. Clement B. Owler A. Depaulis R. Bandler Convergence of deep somatic and visceral nociceptive information onto a discrete ventrolateral midbrain periaqueductal gray region Neuroscience 61 1994 727 732
32. J.J. Kim R.A. Rison M.S. Fanselow Effects of amygdala, hippocampus, and periaqueductal gray lesions on short- and long-term contextual fear Behav. Neurosci. 107 1993 1093 1098
33. J.E. LeDoux J. Iwata P. Cicchetti D.J. Reis Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear J. Neurosci. 8 1988 2517 2529
34. J.C. Liebeskind G. Guilbaud J. Besson J.L. Oliveras Analgesia from electrical stimulation of the periaqueducatal gray matter in the cat: Behavioral observations and inhibitory effects on spinal cord interneurons Brain Res. 50 1973 441 446
35. J.M. Liebman D.J. Mayer J.C. Liebeskind Mesencephalic central gray lesions and fear-motivated behavior in rats Brain Res. 23 1970 353 370
36. T.A. Lovick Integrated activity of cardiovascular and pain regulatory systems: Role in adaptive behavioural responses Prog. Neurobiol. 40 1993 631 644
37. P. Mason H.L. Fields Axonal trajectories and terminations of on- and off-cells in the cat lower brainstem J. Comp. Neurol. 288 1989 185 207
38. M.M. Morgan M.S. Gold J.C. Liebeskind C. Stein Periaqueductal gray stimulation produces a spinally mediated, opioid antinociception for the inflamed hindpaw of the rat Brain Res. 545 1991 17 23
39. M.M. Morgan M.M. Heinricher H.L. Fields Circuitry linking opioid-sensitive nociceptive modulatory systems in periaqueductal gray and spinal cord with rostral ventromedial medulla Neuroscience 47 1992 863 871
40. M.M. Morgan J.C. Liebeskind Site specificity in the development of tolerance to stimulation-produced analgesia from the periaqueductal gray matter of the rat Brain Res. 425 1987 356 359
41. M.M. Morgan J.H. Sohn J.C. Liebeskind Stimulation of the periaqueductal gray matter inhibits nociception at the supraspinal as well as spinal level Brain Res. 502 1989 61 66
42. M.M. Morgan P.K. Whitney M.S. Gold Immobility and flight associated with antinociception produced by activation of the ventral and lateral/dorsal regions of the rat periaqueductal gray Brain Res. 804 1998 159 166
43. G. Paxinos C. Watson The Rat Brain in Stereotaxic Coordinates 2nd Edition 1986 Academic Press Sydney
44. G.J. Prieto J.T. Cannon J.C. Liebeskind N. raphe magnus lesions disrupt stimulation-produced analgesia from ventral but not dorsal midbrain areas in the rat Brain Res. 261 1983 53 57
45. J. Sandkühler G.F. Gebhart Relative contributions of the nucleus raphe magnus and adjacent medullary reticular formation to the inhibition by stimulation in the periaqueductal gray of a spinal nociceptive reflex in the pentobarbital-anesthetized rat Brain Res. 305 1984 77 87
46. V. Tortorici C.S. Robbins M.M. Morgan Tolerance to the antinociceptive effect of morphine microinjections into the ventral but not lateral-dorsal periaqueductal gray of the rat Behav. Neurosci. 113 1999 833 839
47. G. Urca R.L. Nahin J.C. Liebeskind Glutamate-induced analgesia: Blockade and potentiation by naloxone Brain Res. 192 1980 523 530
48. E.J. Van Bockstaele V.A. Pieribone G. Aston-Jones Diverse afferents converge on the nucleus paragigantocelluaris in the rat ventrolateral medulla: Retrograde and anterograde studies J. Comp. Neurol. 290 1989 561 584
49. W.D. Willis L.H. Haber R.F. Martin Inhibition of spinothalamic tract cells and interneurons by brainstem stimulation in the monkey J. Neurophysiol. 40 1977 968 981
50. T.L. Yaksh T.A. Rudy Narcotic analgetics: CNS sites and mechanisms of action as revealed by intracerebral injection techniques Pain 4 1978 299 359
51. S.P. Zhang R. Bandler P. Carrive Flight and immobility evoked by excitatory amino acid microinjection within distinct parts of the subtentorial midbrain periaqueductal gray of the cat Brain Res. 520 1990 73 82
52. S.P. Zhang P.J. Davis P. Carrive R. Bandler Control of respiration and patterns of muscle activity associated with vocalization in the midbrain periaqueductal gray of the cat J. Physiol. 72 1994 1337 1356
53. W. Zieglgänsberger Opioid actions on mammalian spinal neurons Int. Rev. Neurobiol. 25 1984 243 275