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1
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For recent reviews on β-lactam antibiotics, see: (a)
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For recent reviews on β-lactam antibiotics, see: (a) Maiti, S. N.; Phillips, O. A.; Micetich, R. G.; Livermore, D. M. Curr. Med. Chem. 1998, 5, 441. (b) Berks, A. H. Tetrahedron 1996, 52, 331. (c) Southgate, R.; Branch, C.; Coulton, S.; Hunt, E. Recent Prog. Chem. Synth. Antibiot. Relat. Microb. Prod. 1993, 621.
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For recent reviews on β-lactam antibiotics, see: (a) Maiti, S. N.; Phillips, O. A.; Micetich, R. G.; Livermore, D. M. Curr. Med. Chem. 1998, 5, 441. (b) Berks, A. H. Tetrahedron 1996, 52, 331. (c) Southgate, R.; Branch, C.; Coulton, S.; Hunt, E. Recent Prog. Chem. Synth. Antibiot. Relat. Microb. Prod. 1993, 621.
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For recent reviews on β-lactam antibiotics, see: (a) Maiti, S. N.; Phillips, O. A.; Micetich, R. G.; Livermore, D. M. Curr. Med. Chem. 1998, 5, 441. (b) Berks, A. H. Tetrahedron 1996, 52, 331. (c) Southgate, R.; Branch, C.; Coulton, S.; Hunt, E. Recent Prog. Chem. Synth. Antibiot. Relat. Microb. Prod. 1993, 621.
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4
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84991428166
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This azetidinone known as 'azetidon-Kaneka' is extensively used as a versatile building block for the syntheses of carbapenems and other β-lactam antibiotics. For synthetic routes to these compounds, see Ref. 1b
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This azetidinone known as 'azetidon-Kaneka' is extensively used as a versatile building block for the syntheses of carbapenems and other β-lactam antibiotics. For synthetic routes to these compounds, see Ref. 1b.
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For reactions of enolate of diacyl ylides, see: (a) Wasserman, H. H.; Lee, G. M. Tetrahedron Lett. 1994, 35, 9783. (b) Cooke, M. P., Jr. J. Org. Chem. 1982, 47, 4963. (c) Cooke, M. P., Jr.; Burman, D. L. J. Org. Chem. 1982, 47, 4955. (d) Taylor, J. D.; Wolf, J. F. J. Chem. Soc., Chem. Commun. 1972, 876.
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For reactions of enolate of diacyl ylides, see: (a) Wasserman, H. H.; Lee, G. M. Tetrahedron Lett. 1994, 35, 9783. (b) Cooke, M. P., Jr. J. Org. Chem. 1982, 47, 4963. (c) Cooke, M. P., Jr.; Burman, D. L. J. Org. Chem. 1982, 47, 4955. (d) Taylor, J. D.; Wolf, J. F. J. Chem. Soc., Chem. Commun. 1972, 876.
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For reactions of enolate of diacyl ylides, see: (a) Wasserman, H. H.; Lee, G. M. Tetrahedron Lett. 1994, 35, 9783. (b) Cooke, M. P., Jr. J. Org. Chem. 1982, 47, 4963. (c) Cooke, M. P., Jr.; Burman, D. L. J. Org. Chem. 1982, 47, 4955. (d) Taylor, J. D.; Wolf, J. F. J. Chem. Soc., Chem. Commun. 1972, 876.
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For reactions of enolate of diacyl ylides, see: (a) Wasserman, H. H.; Lee, G. M. Tetrahedron Lett. 1994, 35, 9783. (b) Cooke, M. P., Jr. J. Org. Chem. 1982, 47, 4963. (c) Cooke, M. P., Jr.; Burman, D. L. J. Org. Chem. 1982, 47, 4955. (d) Taylor, J. D.; Wolf, J. F. J. Chem. Soc., Chem. Commun. 1972, 876.
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Product 30 is related to the tricyclic hydroxy cephem derivative 33 reported to have antibiotic activity
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