Kinetic and crystallographic studies on the active site Arg289Lys mutant of flavocytochrome b2 (yeast L-lactate dehydrogenase)

Biochemistry

Volumn 39, Issue 12, 2000, Pages 3266-3275

  Mowat, Christopher G ^a   Beaudoin, Isabelle ^b   Durley, Rosemary C E ^c   Barton, John D ^c   Pike, Andrew D ^a   Chen, Zhi Wei ^c   Reid, Graeme A ^a   Chapman, Stephen K ^a   Mathews, F Scott ^c   Lederer, Florence ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b LABORATOIRE D ENZYMOLOGIE ET BIOCHIMIE STRUCTURALES   (France)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LACTATE DEHYDROGENASE (CYTOCHROME);

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME KINETICS; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

ARGININE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; KINETICS; L-LACTATE DEHYDROGENASE; L-LACTATE DEHYDROGENASE (CYTOCHROME); LACTIC ACID; LYSINE; MANDELIC ACIDS; MUTAGENESIS, SITE-DIRECTED; OXALATES; PYRUVATES; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SUBSTRATE SPECIFICITY; SULFITES;

ESCHERICHIA COLI; FELIS CATUS; SACCHAROMYCES CEREVISIAE;

EID: 0034724320     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9925975     Document Type: Article

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