Involvement of Ca2+/calmodulin-dependent protein kinase II in neurite outgrowth induced by cAMP treatment and serum deprivation in a central nervous system cell line, CAD derived from rat brain

Neuroscience Letters

Volumn 293, Issue 2, 2000, Pages 111-114

  Donai, Hitomi ^a   Nakamura, Miki ^a   Sogawa, Yoshimi ^a   Wang, James K T ^b   Urushihara, Masato ^a   Yamauchi, Takashi ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alternative splicing; Ca2+ calmodulin dependent protein kinase II (CaM kinase II); CNS cell line (CAD); Isoform; Neural differentiation; Neurite outgrowth

Indexed keywords

CYCLIC AMP; ISOENZYME; PROTEIN KINASE (CALCIUM,CALMODULIN) II; CALMODULIN DEPENDENT PROTEIN KINASE II; CALMODULIN-DEPENDENT PROTEIN KINASE II; PROTEIN KINASE (CALCIUM,CALMODULIN);

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CELL LINE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SERUM; ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; BRAIN; CULTURE MEDIUM; CYTOLOGY; ENZYMOLOGY; GENETICS; MOLECULAR GENETICS; NEURITE; PHYSIOLOGY;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BRAIN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL LINE; CULTURE MEDIA, SERUM-FREE; CYCLIC AMP; ISOENZYMES; MOLECULAR SEQUENCE DATA; NEURITES; RATS;

EID: 0034721606     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)01500-7     Document Type: Article

References (19)

1. 2+/calmodulin-dependent protein kinase determined by molecular cloning. Proc. Natl. Acad. Sci. USA. 84:1987;1794-1798.
2. Braun A.P., Schulman H. The multifunctional calmodulin-dependent protein kinase: from form to function. Annu. Rev. Physiol. 57:1995;417-445.
3. 2+/calmodulin-dependent protein kinase II in Neuro2a and NG108-15 neuroblastoma cell lines promotes neurite outgrowth and growth cone motility. J. Neurosci. 13:1993;559-567.
4. Kelly P.T., Shields S., Conway K., Yip R., Burgin K. Developmental changes in calmodulin-kinase II activity at brain synaptic junctions: alterations in holoenzyme composition. J. Neurochem. 49:1987;1927-1940.
5. Kennedy M.B., Greengard P. Two calcium/calmodulin-dependent protein kinases, which are highly concentrated in brain, phosphorylate protein I at distinct sites. Proc. Natl. Acad. Sci. USA. 78:1981;1293-1297.
6. Lazaroff M., Qi Y., Chikaraishi D.M. Differentiation of a catecholaminergic CNS cell line modifies tyrosine hydroxylase transcriptional regulation. J. Neurochem. 71:1998;51-59.
7. Lin C.R., Kapiloff M.S., Durgerian S., Tatemoto K., Russo A.F., Hanson P., Schulman H., Rosenfeld M.G. Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase. Proc. Natl. Acad. Sci. USA. 84:1987;5962-5966.
8. Lisman J. The CaM kinase II hypothesis for the storage of synaptic memory. Trends Neurosci. 17:1994;406-412.
9. Mayer P., Mohlig M., Schatz H., Pfeiffer A. Additional isoforms of multifunctional calcium/calmodulin-dependent protein kinase II in rat heart tissue. Biochem. J. 298:1994;757-758.
10. Mueller B.K. Growth cone guidance: first steps towards a deeper understanding. Annu. Rev. Neurosci. 22:1999;351-388.
11. 2+/calmodulin-dependent protein kinase II in neuroblastoma cells - H7 promotes neurite outgrowth. Brain Res. 766:1997;129-141.
12. Qi Y., Wang J.K.T., McMillan M., Chikaraishi D.M. Characterization of a CNS cell line, CAD, in which morphological differentiation is initiated by serum deprivation. J. Neurosci. 17:1997;1217-1225.
13. 2+/calmodulin-dependent protein kinase II regulates atrial natriuretic factor gene expression in ventricular myocytes. J. Biol. Chem. 272:1997;31203-31208.
14. 2+/calmodulin-dependent protein kinase II: differential expression in rat brain and aorta. J. Biol. Chem. 268:1993;14443-14449.
15. Srinivasan M., Edman C.F., Schulman H. Alternative splicing introduces a nuclear signal that targets multifunctional CaM kinase II to the nucleus. J. Cell Biol. 126:1994;839-852.
16. 2+/calmodulin-dependent protein kinase II α and β proteins in soluble and particulate fractions of the rat brain. Brain Res. 593:1992;97-104.
17. Tobimatsu T., Kameshita I., Fujisawa H. Molecular cloning of the cDNA encoding the third polypeptide (γ) of brain calmodulin-dependent protein kinase II. J. Biol. Chem. 263:1988;16082-16086.
18. Tobimatsu T., Fujisawa H. Tissue-specific expression of four types of rat calmodulin-dependent protein kinase II mRNAs. J. Biol. Chem. 264:1989;17907-17912.
19. Yamauchi T., Fujisawa H. Evidence for three distinct forms of calmodulin-dependent protein kinases from rat brain. FEBS Lett. 116:1980;141-144.