Increased expression of the lymphocyte early activation marker CD69 in peripheral blood correlates with histologic evidence of cardiac allograft rejection

Transplantation

Volumn 69, Issue 10, 2000, Pages 2102-2107

  Schowengerot, Kenneth O ^a   Fricker, F Jay ^a   Bahjat, Keith S ^a   Kuntz, Sean T ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN;

ADOLESCENT; ANTIGEN EXPRESSION; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FLOW CYTOMETRY; GRAFT REJECTION; HEART MUSCLE BIOPSY; HEART TRANSPLANTATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

ADOLESCENT; ADULT; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; B-LYMPHOCYTES; BIOLOGICAL MARKERS; BIOPSY; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHILD; FLOW CYTOMETRY; GRAFT REJECTION; HEART TRANSPLANTATION; HUMANS; LYMPHOCYTE ACTIVATION; T-LYMPHOCYTES; TRANSPLANTATION, HOMOLOGOUS;

EID: 0034720679     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Testi R, D'Ambrosio D, De Maria R, Santoni A. The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells. Immunol Today 1994; 15: 479.
2. Craston R, Koh M, McDermott A, Ray N, Prentice HG, Lowdell MW. Temporal dynamics of CD69 expression on lymphoid cells. J Immunol Methods 1997; 209: 37.
3. Mardiney M, Brown MR, Fleisher TA: Measurement of T-cell CD69 expression: a rapid and efficient means to assess mitogen- or antigen-induced proliferative capacity in normals. Cytometry 1996; 26: 305.
4. Krowka JF, Cuevas B, Maron DC, Steimer KS, Ascher MS, Sheppard HW. Expression of CD69 after in vitro stimulation: a rapid method for quantitating impaired lymphocyte responses in HIV-infected individuals. J Acquir Immune Defic Syndr Hum Retrovirol 1996; 11: 95.
5. Crispin JC, Martinez A, de Pablo P, Velasquillo C, Alcocer-Varela J. Participation of the CD69 antigen in the T-cell activation process of patients with systemic lupus erythematosus. Scand J Immunol 1998; 48: 196.
6. Su CC, Shau WY, Wang CR, Chuang CY, Chen CY. CD69 to CD3 ratio of peripheral blood mononuclear cells as a marker to monitor systemic lupus erythematosus disease activity. Lupus 1997; 6: 449.
7. Afeltra A, Galeazzi M, Ferri GM, Amoroso A, De Pita O, Porzio F, Bonomo L. Expression of CD69 antigen on synovial fluid T cells in patients with rheumatoid arthritis and other chronic synovitis. Ann Rheum Dis 1993; 52: 457.
8. Sakkas LI, Scanzello C, Johanson N, et al. T cells and T-cell cytokine transcripts in the synovial membrane in patients with osteoarthritis. Clin Diagn Lab Immunol 1998; 5: 430.
9. Santamaria M, Marubayashi M, Arizon JM, et al. The activation antigen CD69 is selectively expressed on CD8+ endomyocardium infiltrating T lymphocytes in human rejecting heart allografts. Hum Immunol 1992; 33: 1.
10. Lim LC, Fiordalisi MN, Mantell JL, Schmitz JL, Folds JD. A whole-blood assay for qualitative and semiquantitative measurements of CD69 surface expression on CD4 and CD8 T lymphocytes using flow cytometry. Clin Diagn Lab Immunol 1998; 5: 392.
11. Billingham ME, Cary NR, Hammond ME, et al. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: Heart Rejection Study Group; the International Society for Heart Transplantation. J Heart Transplant 1990; 9: 587.
12. Grant SC, Lamb WR, Brooks NH, Brenchley PE, Hutchinson IV. Serum cytokines in human heart transplant recipients: is there a relationship to rejection? Transplantation 1996; 62: 480.
13. Dengler TJ, Zimmermann R, Braun K, et al. Elevated serum concentrations of cardiac troponin T in acute allograft rejection after human heart transplantation. J Am Coll Cardiol 1998; 32: 405.
14. Walpoth BH, Celik B, Printzen G, et al. Assessment of troponin-T for detection of clinical cardiac rejection. Transplant Int 1998; 11, Suppl 1: S502.
15. Alexis JD, Lao CD, Selter JG, et al. Cardiac troponin T: a noninvasive marker for heart transplant rejection? J Heart Lung Transplant 1998; 17: 395.
16. Hirsch R, Landt Y, Porter S, et al. Cardiac troponin I in pediatrics: normal values and potential use in the assessment of cardiac injury. J Pediatr 1997; 130: 872.
17. Bruno TF, Buser DE, Syme RM, Woods DE, Mody CH. Pseudomonas aeruginosa exoenzyme S is a mitogen but not a superantigen for human T lymphocytes. Infect Immun 1998; 66: 3072.
18. Terres AM, Pajares JM. An increased number of follicles containing activated CD69+ helper T cells and proliferating CD71+ B cells are found in H. pylori-infected gastric mucosa. Am J Gastroenterol 1998; 93: 579.