Propriospinal afferent and efferent connections of the lateral and medial areas of the dorsal horn (Laminae I-IV) in the rat lumbar spinal cord

Journal of Comparative Neurology

Volumn 422, Issue 2, 2000, Pages 312-325

  Petkó, Mihály ^a   Antal, Miklós ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Immunocytochemistry; Interneurons; Local neural circuits; Neural tracing; Sensory information processing

Indexed keywords

TRACER;

ANIMAL TISSUE; ARTICLE; EFFERENT NERVE; GRAY MATTER; IMMUNOCYTOCHEMISTRY; LUMBAR SPINAL CORD; MALE; NERVE TRACT; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY SYSTEM; SPINAL CORD DORSAL HORN;

AFFERENT PATHWAYS; ANIMALS; AXONS; BIOTIN; BRAIN MAPPING; DEXTRANS; EFFERENT PATHWAYS; FLUORESCENT DYES; LUMBAR VERTEBRAE; MALE; PHYTOHEMAGGLUTININS; POSTERIOR HORN CELLS; RATS; RATS, WISTAR;

EID: 0034717923     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(20000626)422:2<312::AID-CNE11>3.0.CO;2-A     Document Type: Article

References (69)

1. Antal M, Petkó M. 1996. Propriospinal afferent and efferent connections of the lateral and medial subdivisions of the dorsal horn (laminae I-IV) in the rat lumbar spinal cord. Soc Neurosci Abstr 22:860.
2. Antal M, Freund TF, Polgár E. 1990. Calcium-binding proteins, parvalbumin and calbindin-D28k immunoreactive neurons in the rat spinal cord and dorsal root ganglia: a light and electron microscopic study. J Comp Neurol 295:467-484.
3. Antal M, Petkó M, Polgér E, Heizmann CW, Storm-Mathisen J. 1996. Direct evidence of an extensive GABAergic innervation of the spinal dorsal horn by fibers descending from the rostral ventromedial medulla. Neuroscience 73:509-518.
4. Apkarian AV, Hodge CJ. 1989. Primate spinothalamic pathways: I. A quantitative study of the cells of origin of the spinothalamic pathway. J Comp Neurol 288:447-473.
5. Basbaum AI, Fields HL. 1984. Endogenous pain control system: brainstem spinal pathways and endorphin circuitry. Annu Rev Neurosci 7:309-338.
6. Bice TN, Beal JA. 1997a. Quantitative and neurogenic analysis of the total population and subpopulations of neurons defined by axon projection in the superficial dorsal horn of the rat lumbar spinal cord. J Comp Neurol 388:550-564.
7. Bice TN, Beal JA. 1997b. Quantitative and neurogenic analysis of neurons with supraspinal projections in the superficial dorsal horn of the rat lumbar spinal cord. J Comp Neurol 388:565-574.
8. Chen S, Aston-Jones G. 1998. Axonal collateral-collateral transport of tract tracers in brain neurons: false anterograde labelling and useful tool. Neuroscience 82:1151-1163.
9. Chung K, Briner RP, Carlton SM, Westlund KN. 1989. Immunohistochemical localization of seven different peptides in the human spinal cord. J Comp Neurol 280:158-170.
10. Cliffer KD, Giesler GJ Jr. 1988. PHA-L can be transported anterogradely through fibers of passage. Brain Res 458:185-191.
11. Colvin LA, Mark MA, Duggan AW. 1996. Bilaterally enhanced dorsal horn postsynaptic currents in a rat model of peripheral mononeuropathy. Neurosci Lett 207:29-32.
12. Cruz F, Lima D, Coimbra A. 1993. Periterminal synaptic organization of primary afferents in laminae I and IIo of the rat spinal cord as shown after anterograde HRP labelling. J Neurocytol 22:191-204.
13. Devor M, Claman D. 1980. Mapping and plasticity of acid phosphatase afferents in the rat dorsal horn. Brain Res 190:17-28.
14. Dolleman-Van der Weel MJ, Wouterlood FG, Witter MP. 1994. Multiple anterograde tracing, combining Phaseolus vulgaris leucoagglutinin with rhodamine-and biotin-conjugated dextran amine. J Neurosci Methods 51:9-21.
15. Donaldson LF, Harmar AJ, McQueen DS, Seckl JR. 1992 Increased expression of preprotachykinin, calcitonin gene-related peptide, but not vasoactive intestinal peptide messenger RNA in dorsal root ganglia during the development of adjuvant monoarthritis in the rat. Brain Res Mol Brain Res 16:143-149
16. Fields HL, Heinricher MM, Mason P. 1991. Neurotransmitters in nociceptive modulatory circuits. Annu Rev Neurosci 14:219-245.
17. Fitzgerald M. 1982. The contralateral input to the dorsal horn of the spinal cord in the decerebrate spinal rat. Brain Res 236:275-287.
18. Fuji K, Senba E, Ueda Y, Tohyama M. 1983. Vasoactive intestinal polypeptide (VIP)-containing neurons in the spinal cord of the rat and their projections. Neurosci Lett 37:51-55.
19. Fuji K, Senba E, Tohyama M, Fuji S, Ueda Y, Wu J-W. 1985. Distribution, ontogeny and fiber connections of cholocystokinin-8, vasoactive intestinal polypeptide and γ-aminobutyrate-containing neuron systems in the rat spinal cord: a immunohistochemical analysis. Neuroscience 14:881-896.
20. Gerfen CR, Sawchenko PE. 1984. A method for anterograde neuroanatomical tracing that shows the detailed morphology of neurons, their axons and terminals: Immunohistochemical localization of an axonally transported plant lectin, Phaseolus vulgaris leucoagglutinin (PHA-L). Brain Res 290:219-238.
21. Gerfen CR, Sawchenko PE. 1985. A method for anterograde axonal tracing of chemically specified circuits in the central nervous system: combined Phaseolus vulgaris leucoagglutinin (PHA-L) tract tracing and immunocytochemistry. Brain Res 343:144-150.
22. Gibson SJ, Polak JM, Bloom SR, Wall PO. 1981. The distribution of nine peptides in rat spinal cord with special emphasis on the substantia gelatinosa and on the area around the central canal (lamina X). J Comp Neurol 201:65-79.
23. Gibson SJ, Polak JM, Bloom SR, Sabate IM, Mulderry PM, Ghatei MA, McGregor GP, Morrison JFB, Kelly JS, Evans RM, Rosenfeld MG. 1984. Calcitonin gene-related peptide immunoreactivity in the spinal cord of man and of eight other species. J Neurosci 4:3101-3111.
24. Granum SL. 1986. The spinothalamic system of the rat. I. Locations of cells of origin. J Comp Neurol 247:159-180.
25. Grove EA, Domesick VB, Nauta WHH. 1986. Light microscopic evidence of striatal input to intrapallidal neurons of cholinergic cell group Ch4 in the rat: a study employing the anterograde tracer Phaseolus vulgaris leucoagglutinin (PHA-L). Brain Res 367:379-384.
26. Hancock MB. 1984. Visualization of peptide-immunoreactive processes on serotonin-immunoreactive cells using two-colour immunoperoxidase staining. J Histochem Cytochem 32:311-314.
27. Herdegen T, Leah JD, Manisali A, Bravo R, Zimmermann M. 1991a. C-jun-like immunoreactivity in the CNS of the adult rat: basal and transynaptically induced expression of an immediate-early gene. Neuroscience 41:643-654.
28. Herdegen T, Tölle TR, Bravo R, Zieglnsberger W, Zimmermann M. 1991b. Sequential expression of JUN B, JUN D and FOS B proteins in rat spinal neurons: cascade of transcriptional operations during nociception. Neurosci Lett 129:221-224.
29. Keller A, White EL, Cipolloni PB. 1985. The identification of the thalamocortical axon terminal in the mouse SmI cortex using immunocytochemistry of anterogradely transported lectin (Phaseolus vulgaris leucoagglutinin). Brain Res 343:159-165.
30. Light AR, Perl ER. 1979 Reexamination of the dorsal root projection to the spinal dorsal horn including observations on the differential termination of coarse and fine fibers. J Comp Neurol 186:117-132.
31. Lima D, Coimbra A. 1988. The spinothalamic system of the rat: structural types of retrograde labelled neurons in the marginal zone (lamina I). Neuroscience 27:215-230.
32. Lima D, Coimbra A. 1989. Morphological types of spinomesencephalic neurons in the marginal zone (lamina I) of the rat spinal cord, as shown after retrograde labeling with cholera toxin subunit B. J Comp Neurol 279:327-339.
33. Lima D, Coimbra A. 1990. Structural types of marginal (lamina I) projecting to the dorsal reticular nucleus of the medulla oblongata. Neuroscience 34:591-606.
34. Lima D, Coimbra A. 1991a. The spinoreticular system of the rat: projections from the SDH and structural characterization of marginal neurons involved. Neuroscience 45:137-152.
35. Lima D, Coimbra A. 1991b. Neurons in the substantia gelatinosa Rolandi (lamina II) project to the caudal ventrolateral reticular formation of the medulla oblongata in the rat. Neurosci Lett 132:16-18.
36. Mapp PI, Terenghi G, Walsh DA, Chen ST, Cruwys SC, Garrett N, Kidd BL, Polak JM, Blake DR. 1993. Monoarthritis in the rat knee induces bilateral and time-dependent changes in substance P and calcitonin gene-related peptide immunoreactivity in the spinal cord. Neuroscience 57:1091-1096.
37. Marlier L, Sandillon F, Poulat P, Rajaofetra N, Geffard M, Privat E. 1991. Serotonergic innervation of the dorsal horn of rat spinal cord: Light and electron microscopic immunocytochemical study. J Neurocytol 20:310-322.
38. Menétrey D, Roudier F, Besson JM. 1983. Spinal neurons reaching the lateral reticular nucleus as studied in the rat by retrograde transport of horseradish peroxidase. J Comp Neurol 220:439-452.
39. Menétrey D, De Pommery J, Thomasset M, Baimbridge KG. 1992. Calbindin-D28K (CaBP28k)-like immunoreactivity in ascending projections. II. Spinal projections to brain stem and mesencephalic areas. Eur J Neurosci 4:70-76.
40. Molander C, Xu Q, Grant G. 1984. The cytoarchitectonic organization of the spinal cord in the rat. I. The lower thoracic and lumbosacral cord. J Comp Neurol 230:133-141.
41. Molander C, Grant G. 1985. Cutaneous projections from the rat hindlimb foot to the substantia gelatinosa of the spinal cord studied by transganglionic transport of WGA-HRP conjugate. J Comp Neurol 237:476-484.
42. Molander C, Grant G. 1986. Laminar distribution and somatotopic organization of primary afferent fibers from hindlimb nerves in the dorsal horn: a study by transganglionic transport of horseradish peroxidase in the rat. Neuroscience 19:297-312.
43. Perl ER. 1980. Afferent basis of nonciception and pain: evidence from the characteristics of sensory receptors and their projections to the spinal dorsal horn. In: Bonica JJ, editor. Pain. New York: Raven Press. p 19-45.
44. Price DD. 1984. Dorsal horn mechanisms of pain. In: Davidoff RA, editor. Handbook of the spinal cord. Vols. 2 and 3. Anatomy and physiology. New York: Marcel Dekker Inc. p 751-777.
45. Rajakumar N, Elisevich K, Flumerfelt BA. 1993. Biotinylated dextran: a versatile anterograde and retrograde neuronal tracer. Brain Res 607: 47-53.
46. Ren K, Ruda MA. 1994. A comparative study of the calcium-binding proteins calbindin-D28K, calretinin, calmodulin and parvalbumin in the rat spinal cord. Brain Res Brain Res Rev 19:163-179.
47. Ren K, Ruda MA. 1996 descending modulation of Fos expression after persistent peripheral inflammation. Neuroreport 7:2186-2190.
48. Réthelyi M. 1984. Synaptic connectivity in the spinal dorsal horn. In: Davidoff RA, editor. Handbook of the spinal cord. Vols. 2 and 3. Anatomy and physiology. New York: Marcel Dekker Inc. p 137-177.
49. Réthelyi M, Szentágothai J. 1969. The large synaptic complexes of the substantia gelatinosa. Exp Brain Res 7:258-274.
50. Réthelyi M, Szentágothai J. 1973. Distribution and connections of afferent fibers in the spinal cord. In: Iggo A, editor. Handbook of sensory physiology. Vol. II. Somato-sensory systems. Berlin, Heidelberg, New York: Springer Verlag. p 207-252.
51. Ruda MA, Bennett GJ, Dubner R. 1986. Neurochemistry and neural circuitry in the dorsal horn. Prog Brain Res 66:219-268.
52. Sandkühler J, Stalzer B, Fu QG. 1993. Characteristics of propriospinal modulation of nociceptive lumbar spinal dorsal horn neurons in the cat. Neuroscience 54:957-967.
53. Scheibel ME, Scheibel AB. 1968. Terminal axonal patterns in cat spinal cord. II. The dorsal horn. Brain Res 9:32-58.
54. Sidibé M, Smith Y. 1996. Differential synaptic innervation of striatofugal neurons projecting to the internal or external segments of the globus pallidus by thalamic afferents in the squirrel monkey. J Comp Neurol 365:445-465.
55. Sluka KA, Dougharty PM, Sorkin LS, Willis WD, Westlund KN. 1992. Neural changes in acute arthritis in monkeys. III. Changes in substance P, calcitonin gene-related peptide and glutamate in the dorsal horn of the spinal cord. Brain Res Brain Res Rev 17:29-38.
56. Solodkin A, Traub RJ, Gebhart GF. 1992. Unilateral hindpaw inflammation produces a bilateral increase in NADPH-diaphorase histochemical staining in the rat lumbar spinal cord. Neuroscience 51:495-499.
57. Sugiura Y, Hosoya Y, Ito R, Kohno K. 1988. Ultrastructural features of functionally identified primary afferent neurons with C (unmyelinated) fibers of the guinea pig: classification of dorsal root ganglion cell type with reference to sensory modality. J Comp Neurol 276:265-278.
58. Swett JE, Woolf CJ. 1985. The somatotopic organization of primary afferent terminals in the superficial laminae of the dorsal horn of the rat spinal cord. J Comp Neurol 231:66-77.
59. Szentágothai J. 1951. Short propriospinal neurons and intrinsic connections of the spinal gray matter. Acta Morphol Acad Sci Hung 1:81-94.
60. Szentágothai J. 1964a. Propriospinal pathways and their synapses. Prog Brain Res 11:155-177.
61. Szentágothai J. 1964b. Neuronal and synaptic arrangement in the substantia gelatinosa Rolandi. J Comp Neurol 122:219-239.
62. Tachibana M, Wenthold RJ, Morioka H, Petralia RS. 1994. Light and electron microscopic immunocytochemical localization of AMPA-selective glutamate receptors in the rat spinal cord. J Comp Neurol 344:431-454.
63. Veenman CL, Reiner A, Honig MG. 1992. Biotinylated dextran amine as an anterograde tracer for single-and double-labeling studies. J Neurosci Methods 41:239-254.
64. Williams S, Evan GI, Hunt SP. 1990. Changing patterns of c-Fos induction in spinal neurons following thermal cutaneous stimulation in the rat. Neuroscience 36:73-81.
65. Willis WD. 1985. Pain and headache. Vol. 8. The pain system. The neural basis of nociceptive transmission in the mammalian nervous system. New York: S. Kruger.
66. Willis WD, Kenshalo DR Jr, Leonard RB. 1979. The cells of origin of the primate spinothalamic tract. J Comp Neurol 188:543-574.
67. Woolf CJ, Fitzgerald M. 1986. Somatotopic organization of cutaneous afferent terminals and dorsal horn neuronal receptive fields in the superficial and deep laminae of the rat lumbar spinal cord. J Comp Neurol 251:517-531.
68. Wouterlood FG, Groenewegen HJ. 1985. Neuroanatomical tracing by use of Phaseolus vulgaris-leucoagglutinin (PHA-L): electron microscopy of PHA-L-filled neuronal somata, dendrites, axons and axon terminals. Brain Res 326:188-191.
69. Wouterlood FG, Bol JGJM, Steinbush HWM. 1987. Double-label immunocytochemistry: combination of anterograde tracing with Phaseolus vulgaris leucoagglutinin and enzyme immunocytochemistry of the target neurons. J Histochem Cytochem 35:817-823.