Epalons: 6-substituted derivatives of 7-norepiallopregnanolone

Tetrahedron

Volumn 56, Issue 22, 2000, Pages 3559-3565

  Kasal, Alexander ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

Epoxides; Halohydrins; Isomerisation; Mitsunobu reaction; Steroids

Indexed keywords

3ALPHA 5,6BETA EPOXY 7 NOR 5BETA PREGNAN 20 ONE; 3ALPHA HYDROXY 5,6 EPOXY 7 NOR 5ALPHA PREGNAN 20 ONE; 3ALPHA HYDROXY 7 NOR 5ALPHA PREGNANE 6,20 DIONE; EPALON DERIVATIVE; PREGNANE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; ISOMERISM; PRIORITY JOURNAL; REACTION ANALYSIS; STRUCTURE ANALYSIS;

EID: 0034717323     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(00)00263-5     Document Type: Article

References (22)

1. For a recent review on neuropsychopharmacological properties of neuroactive steroids see Rupprecht, A.; Holsboer, F. Steroids 1999, 64, 83-91.
2. Chodounská H., Kasal A. Coll. Czech. Chem. Commun. 63:1998;1543-1548.
3. Slavíková B., Kasal A., Buděšínský M. Coll. Czech. Chem. Commun. 64:1999;1125-1143.
4. Slavíková B., Kasal A. Coll. Czech. Chem. Commun. 64:1999;1479-1484.
5. Kasal A. Coll. Czech. Chem. Commun. 64:1999;1471-1478.
6. Shen W., Mennerick S., Zorumski E.C., Covey D., Zorumski C.F. Neuropharmacology. 38:1999;267-271.
7. Robel P., Baulieu E.E. Trends Endocrinol. Metab. 5:1996;1-8.
8. Anderson A., Boyd A.C., Byford A., Campbell A.C., Gemmell D.K., Hamilton N.M., Hill D.R., Hill-Venning C., Lambert J.J., Maidment M.S., May V., Marshall R.J., Peters J.A., Rees D.C., Stevenson D., Hardy S. J. Med. Chem. 40:1997;1668-1681.
9. Hawkinson J.E., Acosta-Burruel M., Yang K.C., Hogenkamp D.J., Chen J.S., Lan N.C., Drewe J.A., Whittemore E.C., Woodward R.M., Carter R.B., Upasani R.B. J. Pharm. Exp. Ther. 287:1998;198-207.
10. Joska J., Achrem A.A., Fajkoš J., Šorm F. Collect. Czech. Chem. Commun. 26:1961;2050-2057.
11. de Epifanio R., Camargo W., Pinto A.C. Tetrahedron Lett. 29:1988;6403-6406.
12. Joska J., Fajkoš J., Šorm F. Collect. Czech. Chem. Commun. 28:1963;82-100.
13. Kasal A., Polman J., Buděšínský M. Collect. Czech. Chem. Commun. 63:1998;1549-1563.
14. Joska J., Fajkoš J. Collect. Czech. Chem. Commun. 28:1963;2605-2610.
15. Šídová R., Stránský K., Kasal A., Slavíková B., Kohout L. Collect. Czech. Chem. Commun. 63:1998;1528-1542.
16. Dauben W.G., Boswell G.A. Jr., Templeton W., McFarland J.W. J. Am. Chem. Soc. 85:1963;2302-2305.
17. Morisawa Y. Chem. Pharm. Bull. 12:1964;1066-1071.
18. Kerwin, J.F. USP 3, 072 681; Chem. Abstr. 1963, 59, 1723f.
19. Kerwin, J.F. USP 3, 072 681; Chem. Abstr. 1963, 59, 1723f.
20. Marshall C.W., Ray R.E., Laos I., Riegel B. J. Am. Chem. Soc. 79:1957;6308-6313.
21. Joska J., Šorm F. Collect. Czech. Chem. Commun. 23:1958;1377-1381.
22. Cabrera A., Rosas N., Marquez C., Salmon M., Angelez E., Miranda R., Lozano R. Gazz. Chim. Ital. 121:1991;127-130.