Synthesis of imbiline 1, a tetracyclic aza-aromatic alkaloid

Tetrahedron Letters

Volumn 41, Issue 9, 2000, Pages 1481-1482

  Kitahara, Yoshiyasu ^a   Mochii, Masaaki ^a   Mori, Masakazu ^a   Kubo, Akinori ^a  

^a MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Alkaloids; Cyclisation; Naphthyridines; Oxidation

Indexed keywords

ALKALOID; AROMATIC COMPOUND; IMBILINE 1; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; OXIDATION; REACTION ANALYSIS; SYNTHESIS;

EID: 0034716560     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)02322-9     Document Type: Article

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9. An attempted reaction of 8 with n-butyllithium in tetrahydrofuran followed by ethyl chloroformate failed, giving 2-(n-butyl)-6-methoxy-4-methylbenzo[h]quinoline in 76% yield.
10. 10-H).
11. 4).