The structural basis of dynamic cell adhesion: Heads, tails, and allostery

Experimental Cell Research

Volumn 261, Issue 1, 2000, Pages 37-43

  Liddington, Robert C ^a   Bankston, Laurie A ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CATENIN; BETA CATENIN; CADHERIN; CALCIUM ION; GUANOSINE TRIPHOSPHATASE; INTEGRIN; LIGAND; MAGNESIUM ION; RHO FACTOR;

CELL ADHESION; CELL MEMBRANE; CRYSTAL STRUCTURE; CYTOSKELETON; ELECTRON MICROSCOPY; HYDRODYNAMICS; LIGAND BINDING; PRIORITY JOURNAL; SHORT SURVEY; SIGNAL TRANSDUCTION;

EID: 0034715924     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.2000.5058     Document Type: Article

References (39)

1. The molecular structure of cell adhesion molecules
2. Cell adhesion: Old and new questions
3. The crystal structure of the ligand binding module of axonin-1/TAG-1 suggests a zipper mechanism for neural cell adhesion
4. Integrin αIIbβ3 reconstituted into lipid bilayers is non-clustered in its activated state but clusters after fibrinogen binding
5. Integrins: Versatility, modulation, and signalling in cell adhesion
6. Effects of ligand-mimetic peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on α IIb β 3 integrin conformation and oligomerization
7. New insights into integrin-ligand interaction
8. Integrin cytoplasmic domains mediate inside-out signal transduction
9. Structural basis of collagen recognition by integrin α2β1
10. Two functional states of the CD11b A-domain: Correlations with key features of two Mn2+-complexed crystal structures
11. Conformational changes in tertiary structure near the ligand binding site of an integrin I domain
12. Computational design of an integrin I domain stabilized in the open high affinity conformation
13. Two conformations of the integrin A-domain (I-domain): A pathway for activation?
14. NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding
15. Breaking the integrin hinge
16. Stereochemistry of cooperative mechanisms in hemoglobin
17. αLβ2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule
18. Affinity modulation of platelet integrin αIIbβ3 by β3-endonexin, a selective binding partner of the β3 integrin cytoplasmic tail
19. Binding of paxillin to α4 integrins modifies integrin-dependent biological responses
20. Calcium ions as extracellular messengers
21. Ligand binding results in divalent cation displacement from the α2β1 integrin I domain: Evidence from terbium luminescence spectroscopy
22. Structure of a C-type mannose binding protein complexed with an oligosaccharide
23. Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains
24. The crystal structure of a laminin G-like module reveals the molecular basis of α-dystroglycan binding to laminins, perlecan, and agrin
25. Structure of pentameric human serum amyloid P component
26. 2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation
27. Molecular recognition of the interaction between leukocyte function-associated antigen-1 and soluble ICAM-1 by divalent metal cations
28. Ligand and cation binding are dual functions of a discrete segment of the integrin β3 subunit: Cation displacement is involved in ligand binding
29. An allosteric Ca2+ binding site on the β3 integrins that regulates the dissociation rate for RGD ligands
30. Selective regulation of integrin-cytoskeleton interactions by the tyrosine kinase Src
31. Three-dimensional structure of the tyrosine kinase c-Src
32. Crystal structure of the tyrosine phosphatase SHP-2
33. Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain
34. Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
35. Structure of Bcl-xL-Bak peptide complex: Recognition between regulators of apoptosis
36. Crystal structure of the vinculin tail suggests a pathway for activation
37. Structure of the dimerization and β-catenin-binding region of α-catenin
38. Talin contains three similar vinculin-binding sites predicted to form an amphipathic helix
39. Crystal structure of the I domain from integrin α2β1