Asymmetric synthesis of (R)-(+)-etomoxir via enzymatic resolution

Tetrahedron Asymmetry

Volumn 11, Issue 16, 2000, Pages 3395-3401

  Jew, Sang Sup ^a   Roh, Eun Young ^a   Baek, Eun Young ^a   Mireille, Labrouillére ^a   Kim, Hyung Ook ^a   Jeong, Byeong Seon ^a   Park, Mi Kyoung ^a   Park, Hyeung Geun ^a  

^a Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ETHYLENE OXIDE DERIVATIVE; ETOMOXIR; TRIACYLGLYCEROL LIPASE;

ARTICLE; DRUG PURIFICATION; DRUG SYNTHESIS; ENANTIOMER; ENZYME ACTIVITY; HYDROLYSIS; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; TECHNIQUE;

EID: 0034714141     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0957-4166(00)00304-9     Document Type: Article

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15. 1H NMR, the residue was purified by column chromatography (ethyl acetate:n-hexane=1:2) to give diol and acetate.
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