Characterization of murine coronavirus neutralization epitopes with phage-displayed peptides

Virology

Volumn 271, Issue 1, 2000, Pages 182-196

  Yu, Mathilde W N ^a   Scott, Jamie K ^b   Fournier, Alain ^a   Talbot, Pierre J ^a  

^a UNIVERSITÉ LAVAL   (Canada)

^b SIMON FRASER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN;

AMINO ACID SEQUENCE; ANTIBODY PRODUCTION; ARTICLE; CORONAVIRUS; IMMUNE RESPONSE; PHAGE DISPLAY; PRIORITY JOURNAL; VIRUS NEUTRALIZATION;

ANIMALIA; CORONAVIRUS; FILAMENTOUS BACTERIOPHAGE; MURINAE; MURINE HEPATITIS VIRUS; RNA VIRUSES;

EID: 0034713350     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2000.0310     Document Type: Article

References (72)

1. Armitage P., Berry G. Statistical Methods in Medical Research. 1987;Blackwell Sci. Oxford.
2. Bachmann M. F., Kalinke U., Althage A., Freer G., Burkhart C., Roost H.-P., Aguet M., Hengartner H., Zinkernagel R. M. The role of antibody concentration and avidity in antiviral protection. Science. 276:1997;2024-2027.
3. Balass M., Heldman Y., Cabilly S., Givol D., Katchalski-Katzir E., Fuchs S. Identification of a hexapeptide that mimics a conformation-dependent binding site of acetylcholine receptor by use of a phage-epitope library. Proc. Natl. Acad. Sci. USA. 90:1993;10638-10642.
4. Bastien N., Trudel M., Simard C. Protective immune responses induced by the immunization of mice with a recombinant bacteriophage displaying an epitope of the human respiratory syncytial virus. Virology. 234:1997;118-122.
5. Bonnycastle L. L. C., Mehroke J. S., Rashed M., Gong X., Scott J. K. Probing the basis of antibody reactivity with a panel of constrained peptide libraries displayed by filamentous phage. J. Mol. Biol. 258:1996;747-762.
6. Buchmeier M. J., Lewicki H. A., Talbot P. J., Knobler R. L. Murine hepatitis virus-4 (strain JHM) induced neurologic disease is modulated in vivo by monoclonal antibody. Virology. 132:1984;261-270.
7. Chargelegue D., Obeid O. E., Hsu S. C., Shaw M. D., Denbury A. N., Taylor G., Steward M. W. A peptide mimic of a protective epitope of respiratory syncytial virus selected from a combinatorial library induces virus-neutralizing antibodies and reduces viral load in vivo. J. Virol. 72:1998;2040-2046.
8. Cheever F. S., Daniels J. B., Pappenheimer A. M., Bailey O. T. A murine virus (JHM) causing disseminated encephalomyelitis with extensive destruction of myelin. I. Isolation and biological properties of the virus. J. Exp. Med. 90:1949;181-194.
9. Chen Y.-C. J., Delbrook K., Dealwis C., Mimms L., Mushahwar I. K., Mandecki W. Discontinuous epitopes of hepatitis B surface antigen derived from a filamentous phage peptide library. Proc. Natl. Acad. Sci. USA. 93:1996;1997-2001.
10. Collins A. R., Knobler R. L., Powell H., Buchmeier M. J. Monoclonal antibodies to murine hepatitis virus-4 (strain JHM) define the viral glycoprotein responsible for attachment and cell-cell fusion. Virology. 119:1982;358-371.
11. Cwirla S. E., Peters E. A., Barrett R. W., Dower W. J. Peptides on phage: A vast library of peptides for identifying ligands. Proc. Natl. Acad. Sci. USA. 87:1990;6378-6382.
12. Daniel C., Talbot P. J. Physico-chemical properties of murine hepatitis virus, strain A-59. Arch. Virol. 96:1987;241-248.
13. Daniel C., Talbot P. J. Protection from lethal coronavirus infection by affinity-purified spike glycoprotein of murine hepatitis virus, strain A59. Virology. 174:1990;87-94.
14. Daniel C., Anderson R., Buchmeier M. J., Fleming J. O., Spaan W. J. M., Wege H., Talbot P. J. Identification of an immunodominant linear neutralization domain on the S2 portion of the murine coronavirus spike glycoprotein and evidence that it forms part of a complex tridimensional structure. J. Virol. 67:1993;1185-1194.
15. Daniel C., Lacroix M., Talbot P. J. Mapping of linear antigenic sites on the S glycoprotein of a neurotropic murine coronavirus with synthetic peptides: A combination of nine prediction algorithms fails to identify relevant epitopes and peptide immunogenicity is drastically influenced by the nature of the protein carrier. Virology. 202:1994;540-549.
16. De Groot R. J., Luytjes W., Horzinek M. C., van der Zeijst B. A. M., Spaan W. J. M., Lenstra J. A. Evidence for a coiled-coil structure in the spike of coronaviruses. J. Mol. Biol. 196:1987;963-966.
17. de la Cruz V. F., Lal A. A., McCutchan T. F. Antigenicity and epitope mapping of foreign sequences via genetically engineered filamentous phage. J. Biol. Chem. 263:1988;4318-4322.
18. Demangel C., Lafaye P., Mazie J. C. Reproducing the immune response against the Plasmodium vivax merozoite surface protein 1 with mimotopes selected from a phage-displayed peptide library. Mol. Immunol. 33:1996;909-916.
19. Felici F., Castagnoli L., Musacchio A., Jappelli R., Cesareni G. Selection of antibody ligands from a large library of oligopeptides expressed on a multivalent exposition vector. J. Mol. Biol. 222:1991;301.
20. Felici F., Luzzago A., Folgori A., Cortese R. Mimicking of discontinuous epitopes by phage-displayed peptides. II. Selection of clones recognized by a protective monoclonal antibody against the Bordetella pertussis toxin from phage peptide libraries. Gene. 128:1993;21-27.
21. Forest M., Fournier A. BOP reagent for the coupling of pGlu and Boc His (Tos) in solid phage synthesis. Int. J. Pept. Protein Res. 35:1990;89-94.
22. Forest M., Martel J. C., St-Pierre S., Quirion R., Fournier A. Structural study of the N-terminal segment of neuropeptide-tyrosine. J. Med. Chem. 33:1990;1615-1619.
23. Forget M.-A., Lebel N., Sirois P., Boulanger Y., Fournier A. Biological and molecular analyses of structurally reduced analogues of endothelin-1. Mol. Pharmacol. 49:1990;1071-1079.
24. Folgori A., Tafi R., Meola A., Felici F., Galfré G., Cortese R., Monaci P., Nicosia A. A general strategy to identify mimotopes of pathological antigens using only random peptide libraries and human sera. EMBO J. 13:1994;2236-2243.
25. 2. Int. J. Pept. Protein Res. 31:1988;86-97.
26. Greenwood J., Willis A. E., Perham R. N. Multiple display of foreign peptides on a filamentous bacteriophage. Peptides from Plasmodium falciparum circumsporozoite protein as antigens. J. Mol. Biol. 220:1991;821-827.
27. Grosse B., Siddell S. G. Characterization of a monoclonal antibody resistant variant of MHV. Adv. Exp. Med. Biol. 342:1993;177-182.
28. Harris S. L., Craig L., Mehroke J. S., Rashed M., Zwick M. B., Kenar K., Toone E. J., Greenspan N., Auzanneau F.-I., Marino-Albernas J.-R., Pinto B. M., Scott J. K. Exploring the basis of peptide-carbohydrate crossreactivity: Evidence for discrimination by peptides between closely related anti-carbohydrate antibodies. Proc. Natl. Acad. Sci. USA. 94:1997;2454-2459.
29. Hoess R. H., Mack A. J., Walton H., Reilly T. M. Identification of a structural epitope by using a peptide library displayed on filamentous bacteriophage. J. Immunol. 153:1994;724-729.
30. Holmes K. V., Lai M. M. C. Coronaviridae: The viruses and their replication. Fields B. N., Knipe D. M., Howley P. M. Fields Virology. 1996;1075-1093 Raven Press, Philadelphia.
31. Koolen M. J. M., Borst M. A. J., Horzinek M. C., Spaan W. J. M. Immunogenic peptide comprising a mouse hepatitis virus A59 B-cell epitope and an influenza virus T-cell epitope protects against lethal infection. J. Virol. 64:1990;6270-6273.
32. Kubo H., Yamada Y. K., Taguchi F. Localization of neutralizing epitopes and the receptor-binding site within the amino-terminal 330 amino acids of the murine coronavirus spike protein. J. Virol. 68:1994;5403-5410.
33. Kumanishi T. Brain tumors induced with Rous sarcoma virus, Schmidt-Ruppin strain. I. Induction of brain tumors in adult mice with Rous chicken sarcoma cells. Jpn. J. Exp. Med. 37:1967;461-474.
34. Kunita S., Zhang L., Homberger F. R., Compto S. R. Molecular characterization of the S proteins of two enterotropic murine coronavirus strains. Virus Res. 35:1995;277-289.
35. Laemmli U. K. Cleavage of structural protein during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
36. Lamarre A., Talbot P. J. Protection from lethal coronavirus infection by immunoglobulin fragments. J. Immunol. 154:1995;3975-3984.
37. Lamarre A., Yu M. W. N., Chagnon F., Talbot P. J. A recombinant single chain antibody neutralizes coronavirus infectivity but only slightly delays lethal infection of mice. Eur. J. Immunol. 27:1997;3447-3455.
38. Le-Nguyen D., Heitz A., Castro B. Renin substrates. Part 2. Rapid solid phage synthesis of the ratine sequence tetrapeptide using BOP reagent. J. Chem. Soc. Perkin Trans. 1:1987;1915-1919.
39. Lenstra J. A., Erkens J. H. F., Langeveld J. G. A., Posthumus W. P. A., Meloen R. H., Gebauer F., Correa I., Enjuanes L., Stanley K. K. Isolation of sequences from a random-sequence expression library that mimic viral epitopes. J. Immunol. Methods. 152:1992;149-157.
40. Lutz M. B., Granucci F., Winzler C., Marconi G., Paglia P., Foti M., Abmann C. U., Cairns L., Rescigno M., Ricciardi-Castagnoli P. Retroviral immortalization of phagocytic and dendritic cell clones as a tool to investigate functional heterogeneity. J. Immunol. Methods. 174:1994;269-279.
41. Luytjes W., Sturman L. S., Bredenbeek P. J., Charite J., van der Zeijst B. A., Horzinek M. C., Spaan W. J. Primary structure of the glycoprotein E2 of coronavirus MHV-A59 and identification of the trypsin cleavage site. Virology. 161:1987;479-487.
42. Luytjes W., Geerts D., Posthumus W., Meloen R., Spaan W. Amino acid sequence of a conserved neutralizing epitope of murine coronaviruses. J. Virol. 63:1989;1408-1412.
43. Luzzago A., Felici F., Tramontano A., Pessi A., Cortese R. Mimicking of discontinuous epitopes by phage-displayed peptides. I. Epitope mapping of human H ferritin using a phage library of constrained peptides. Gene. 128:1993;51-57.
44. Manil L., Motté P., Pernas P., Troalen F., Bohuon C., Bellet D. Evaluation of protocols for purification of mouse monoclonal antibodies. J. Immunol. Methods. 90:1986;25-37.
45. Meola A., Delmastro P., Monaci P., Luzzago A., Nicosia A., Felici F., Cortese R., Galfrè G. Derivation of vaccines from mimotopes. Immunologic properties of human hepatitis B virus surface antigen mimotopes displayed on filamentous phage. J. Immunol. 154:1995;3162-3172.
46. Minenkova O. O., Il'ichev A. A., Kishchenko G. P., Il'icheva T. N., Khripin Y. L., Oreshkov S. F., Petrenko V. A. Design of specific immunogen using bacteriophage M13 as carrier. Gene. 128:1993;85-88.
47. Motti C., Nuzzo M., Meola A., Galfré G., Felici F., Cortese R., Nicosia A., Monaci P. Recognition by human sera and immunogenicity of HBsAg mimotopes selected from an M13 phage display library. Gene. 146:1994;191-198.
48. Nakanaga K., Yamanouchi K., Fujiwara K. Protective effect of monoclonal antibodies on lethal mouse hepatitis virus infection in mice. J. Virol. 59:1986;168-171.
49. Oldenburg K. R., Loganathan D., Goldstein I. J., Schultz P. G., Gallop M. A. Peptide ligands for a sugar-binding protein isolated from a random peptide library. Proc. Natl. Acad. Sci. USA. 89:1992;5393-5397.
50. Prezzi C., Nuzzo M., Meola A., Delmastro P., Galfrè G., Cortese R., Nicosia A., Monaci P. Selection of antigenic and immunogenic mimics of hepatitis C virus using sera from patients. J. Immunol. 156:1996;4504-4513.
51. Saeki K., Ohtsuka N., Taguchi F. Identification of spike protein residues of murine coronavirus responsible for receptor-binding activity by use of soluble receptor-resistant mutants. J. Virol. 71:1997;9024-9031.
52. Schmidt I., Skinner M., Siddell S. Nucleotide sequence of the gene encoding the surface projection glycoprotein of coronavirus MHV-JHM. J. Gen. Virol. 68:1987;47-56.
53. Scott J. K., Smith G. P. Searching for peptide ligands with an epitope library. Science. 249:1990;386-390.
54. Scott J. K., Loganathan D., Easley R. B., Gong X., Goldstein I. J. A family of concanavalin A-binding peptides from a hexapeptide epitope library. Proc. Natl. Acad. Sci. USA. 89:1992;5398-5402.
55. Siddell S., Wege H., ter Meulen V. The biology of coronaviruses. J. Gen. Virol. 64:1983;761-776.
56. Smith P., Scott J. K. Libraries of peptides and proteins displayed on filamentous phage. Methods Enzymol. 217:1993;228-257.
57. Spaan W., Cavanagh D., Horzinek M. C. Coronaviruses: Structure and genome expression. J. Gen. Virol. 69:1988;2939-2952.
58. Stephen C. W., Lane D. P. Mutant conformation of p53: Precise epitope mapping using a filamentous phage epitope library. J. Mol. Biol. 225:1992;577-583.
59. Steward M. W., Stanley C. M., Obeid O. E. A mimotope from a solid-phage peptide library induces a measles virus-neutralizing and protective antibody response. J. Virol. 69:1995;7668-7673.
60. Stohlman S. A., Bergmann C. C., van der Veen R. C., Hinton D. R. Mouse hepatitis virus-specific cytotoxic T lymphocytes protect from lethal infection without eliminating virus from the central nervous system. J. Virol. 69:1995;684-694.
61. Stoute J. A., Ballou W. R., Kolodny N., Deal C. D., Wirtz R. A., Lindler L. E. Induction of humoral immune response against Plasmodium falciparum sporozoites by immunization with a synthetic peptide mimotope whose sequence was derived from screening a filamentous phage epitope library. Infect. Immun. 63:1995;934-939.
62. Sturman L. S., Ricard C. S., Holmes K. V. Proteolytic cleavage of the E2 glycoprotein of murine coronavirus: Activation of cell-fusing activity of virions by trypsin and separation of two different 90 K cleavage fragments. J. Virol. 56:1985;904-911.
63. Taguchi F., Ikeda T., Shida H. Molecular cloning and expression of a spike protein of neurovirulent murine coronavirus JHMV variant Cl-2. J. Gen. Virol. 73:1992;1065-1072.
64. Talbot P. J., Dionne G., Lacroix M. Protection against viral encephalitis by a synthetic peptide selected for surface probability. Technological Advances in Vaccine Development, 1988;A. R. Liss, New York. p. 379-389.
65. Vijayakrishnan L., Sarkar S., Roy R. P., Rao K. V. S. B cell responses to a peptide epitope. IV. Subtle sequence changes in flanking residues modulate immunogenicity. J. Immunol. 159:1997;1809-1819.
66. Ward E. S., Güsson D., Griffiths A. D., Jones P. T., Winter G. Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli. Nature. 341:1989;544-546.
67. Weiner L. P. Pathogenesis of demyelination induced by mouse hepatitis virus (JHM virus). Arch. Neurol. 28:1973;298-303.
68. Williams R. K., Jiang G. S., Holmes K. V. Receptor for mouse hepatitis virus is a member of the carcinoembryonic antigen family of glycoproteins. Proc. Natl. Acad. Sci. USA. 88:1991;5533-5536.
69. + T cells. J. Virol. 64:1990;4589-4592.
70. Willis A. E., Perham R. N., Wraith D. Immunological properties of foreign peptides in multiple display on a filamentous bacteriophage. Gene. 128:1993;79-83.
71. Yu M. W. N., Lemieux S., Talbot P. J. Genetic control of anti-idiotypic vaccination against coronavirus infection. Eur. J. Immunol. 26:1996;3230-3233.
72. Zhong G., Smith G. P., Berry J., Brunham R. C. Conformational mimicry of a chlamydial neutralization epitope on filamentous phage. J. Biol. Chem. 269:1994;24183-24188.