Epsilon amino caproic acid inhibits streptokinase-plasminogen activator complex formation and substrate binding through kringle-dependent mechanisms

Biochemistry

Volumn 39, Issue 16, 2000, Pages 4740-4745

  Lin, Lee Fong ^a,c   Houng, Aiilyan ^a   Reed, Guy L ^a,b  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c NEW ENGLAND BIOLABS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOCAPROIC ACID; PLASMINOGEN ACTIVATOR; STREPTOKINASE;

ARTICLE; COMPLEX FORMATION; ENZYME ACTIVATION; ENZYME SUBSTRATE COMPLEX; FIBRINOLYSIS; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN CONFORMATION;

6-AMINOCAPROIC ACID; BINDING SITES; CATALYTIC DOMAIN; HUMANS; INHIBITORY CONCENTRATION 50; KRINGLES; PEPTIDE FRAGMENTS; PLASMIN; PLASMINOGEN; PLASMINOGEN ACTIVATORS; PROTEIN BINDING; SEQUENCE DELETION; STREPTOKINASE; THERMODYNAMICS;

EID: 0034712699     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi992028x     Document Type: Article

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