13C and deuterium isotope effects suggest an aldol cleavage mechanism for L-ribulose-5-phosphate 4-epimerase

Biochemistry

Volumn 39, Issue 16, 2000, Pages 4808-4820

  Lee, Lac V ^a   Vu, Maria V ^a   Cleland, W W ^a  

^a UNIVERSITY OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE; CARBON 13; DEUTERIUM; DIHYDROXYACETONE; EPIMERASE; LIGAND; PHOSPHATE; RIBULOSE PHOSPHATE; 3-HYDROXYBUTANAL; ACETALDEHYDE; ALDOL; CARBON; DRUG DERIVATIVE; GLYCOLALDEHYDE PHOSPHATE; L FUCULOSEPHOSPHATE ALDOLASE; L RIBULOSEPHOSPHATE 4 EPIMERASE; L-FUCULOSEPHOSPHATE ALDOLASE; L-RIBULOSEPHOSPHATE 4-EPIMERASE; LYASE; PENTOSE PHOSPHATE; RHAMNULOSE 1 PHOSPHATE ADOLASE; RHAMNULOSE-1-PHOSPHATE ADOLASE; RIBULOSE 5-PHOSPHATE; XYLULOSE 5 PHOSPHATE; XYLULOSE-5-PHOSPHATE;

ARTICLE; CIRCULAR DICHROISM; ENZYME ACTIVE SITE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITE; CATALYSIS; CHEMISTRY; ENZYMOLOGY; GENETICS; KINETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PH; SEQUENCE ALIGNMENT; STEREOISOMERISM; THERMODYNAMICS;

ESCHERICHIA COLI;

ACETALDEHYDE; ALDEHYDE-LYASES; ALDEHYDES; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITES; CARBOHYDRATE EPIMERASES; CARBON ISOTOPES; CATALYSIS; CIRCULAR DICHROISM; DEUTERIUM; DIHYDROXYACETONE; ESCHERICHIA COLI; HYDROGEN-ION CONCENTRATION; KINETICS; MOLECULAR SEQUENCE DATA; MUTATION; PENTOSEPHOSPHATES; RIBULOSEPHOSPHATES; SEQUENCE ALIGNMENT; STEREOISOMERISM; THERMODYNAMICS;

EID: 0034712585     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi992894+     Document Type: Article

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