A fragment of recombinant GABA(A) receptor α1 subunit forming rosette-like homo-oligomers

Journal of Molecular Biology

Volumn 296, Issue 3, 2000, Pages 739-742

  Xue, Hong ^a   Zheng, Hui ^a   Li, Hoi Ming ^a   Kitmitto, Ashraf ^b   Zhu, Huaimin ^a   Lee, Peggy ^a   Holzenburg, Andreas ^c  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Disulfide bond; Electron microscopy; Homo oligomeric; Laser scattering; Non reducing SDS PAGE

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; MONOMER; OLIGOMER; PROTEIN SUBUNIT; RECOMBINANT PROTEIN;

ARTICLE; CONTROLLED STUDY; DISULFIDE BOND; ELECTRON MICROSCOPY; ESCHERICHIA COLI; GENE OVEREXPRESSION; NONHUMAN; OLIGOMERIZATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN STRUCTURE;

EID: 0034711944     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.3502     Document Type: Article

References (12)

1. The molecular biology of GABA(A) receptors and their structural determinants
2. SPIDER and WEB: Processing and visualization of images in 3D electron microscopy and related fields
3. Preparation techniques for transmission electron microscopy (TEM)
4. GABA(A) receptor channels
5. Nicotinic acetylcholine receptor at 4.6 Å resolution: Transverse tunnels in the channel wall
6. Quaternary structure of the native GABA(A) receptor determined by electron microscopic image analysis
7. Structure and pharmacology of gamma-aminobutyric acid A receptor subtypes
8. Functional domains of GABA(A) receptors
9. The GABA(A) receptors
10. Light scattering and the absolute characterization of macromolecules
11. Fragment of GABA(A) receptor containing key ligand-binding residues overexpressed in Escherichia coli
12. Delineation of a membrane-proximal β-rich domain in GABA(A) receptor by progressive deletions