T84 epithelial cells respond to 5-hydroxytryptamine when grown in serum-free media

European Journal of Pharmacology

Volumn 390, Issue 1-2, 2000, Pages 103-106

  Burleigh, David ^a   Fernandes, Karin ^a   Perrett, David ^b  

^a Div Biomed Sci Sir Alexander F   (United Kingdom)

^b King George V Bldg St B ^*  (United Kingdom)

Author keywords

5 Hydroxytryptamine (5 HT, serotonin); Desensitization; Serum; T84 cell

Indexed keywords

ACETYLCHOLINE; FORSKOLIN; SEROTONIN;

ARTICLE; CELL CULTURE; CELL GROWTH; CELL LINE; CELL SECRETION; CHROMATOGRAPHY; COLON MUCOSA; CONCENTRATION RESPONSE; CONTAMINATION; CONTROLLED STUDY; CULTURE MEDIUM; DESENSITIZATION; DRUG SENSITIVITY; FLUOROMETRY; HUMAN; HUMAN CELL; MONOLAYER CULTURE; PRIORITY JOURNAL; SERUM; SHORT CIRCUIT CURRENT; COLON; CYTOLOGY; DRUG EFFECT; EPITHELIUM CELL;

ACETYLCHOLINE; CELL LINE; COLON; CULTURE MEDIA, SERUM-FREE; EPITHELIAL CELLS; FLUOROMETRY; HUMANS; SEROTONIN;

EID: 0034711863     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00013-3     Document Type: Article

References (12)

1. Aghajanian G.K. Serotonin induced inward current in rat facial motoneurones: evidence for mediating by G proteins but not protein kinase C. Brain Res. 524:1990;171-174.
2. 4 receptor desensitization in colliculi neurons. Mol. Pharmacol. 42:1992;808-816.
3. Bearcroft C.P., Farthing M.J.G., Perrett D. Determination of 5-hydroxytryptamine, 5-hydroxyindoleacetic acid and tryptophan in plasma and urine by HPLC with fluorimetric detection. Biomed. Chromatogr. 9:1995;23-27.
4. Binder H.J., Sandle G.I. Electrolyte transport in the mammalian colon. Johnson L.R. Physiology of the Gastrointestinal Tract. 1994;2133-2171 Raven Press, New York.
5. Borman R.A., Burleigh D.E. Human colonic mucosa possesses a mixed population of 5-hydroxytryptamine receptors. Eur. J. Pharmacol. 309:1996;271-274.
6. Cooke H.J., Reddix R.A. Neural regulation of intestinal electrolyte transport. Johnson L.R. Physiology of the Gastrointestinal Tract. 1994;2083-2132 Raven Press, New York.
7. Dharmsathaphorn K., Madara J.L. Established intestinal cell lines as model systems for electrolyte transport studies. Methods Enzymol. 192:1990;354-389.
8. Dharmsathaphorn K., McRoberts J.A., Mandel K.G., Tisdale L.G., Masui K. A human colonic tumour cell line that maintains vectorial electrolyte transport. Am. J. Physiol. 246:1984;G204-G208.
9. Murakami H., Masui H. Hormonal control of human colon carcinoma cell growth in serum-free medium. Proc. Natl. Acad. Sci. 77:1980;3464-3468.
10. 2 receptor desensitization. Eur. J. Pharmacol. 238:1993;173-180.
11. 2 receptors coupled to phospholipase C in rat aorta: modulation of phosphoinositide turnover by phorbol ester. J. Pharmacol. Exp. Ther. 238:1986;480-485.
12. 2C receptors in functional studies. Pharmacol. Rev. Commun. 9:1997;259-268.