Polypyrimidine tract-binding protein inhibits translation of bip mRNA

Journal of Molecular Biology

Volumn 304, Issue 2, 2000, Pages 119-133

  Kim, Yoon Ki ^a   Hahm, Bumsuk ^a   Jang, Sung Key ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

Bip; IRES; PTB; Translation

Indexed keywords

BINDING PROTEIN; GLUCOSE REGULATED PROTEIN 78; MESSENGER RNA; POLYPYRIMIDINE TRACT BINDING PROTEIN; PYRIMIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENCEPHALOMYOCARDITIS VIRUS; HUMAN; HUMAN CELL; MONKEY; NONHUMAN; PICORNAVIRUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RIBOSOME; RNA TRANSLATION; TRANSLATION INITIATION;

ANIMALIA; ENCEPHALOMYOCARDITIS VIRUS; ORYCTOLAGUS CUNICULUS; PICORNAVIRIDAE;

EID: 0034711379     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4179     Document Type: Article

References (78)

1. Interaction of polypyrimidine tract-binding protein with the 5' noncoding region of the hepatitis C virus RNA genome and its functional requirement in internal initiation of translation
2. Requirement of poly(rC) binding protein 2 for translation of poliovirus RNA
3. The human U1 snRNP-specific U1A protein inhibits polyadenylation of its own pre-mRNA
4. Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas
5. The involvement of a spliceosome component in internal initiation of human rhinovirus RNA translation
6. A factor that specifically binds to the 5'-untranslated region of encephalomyocarditis virus RNA
7. RNA-protein interactions within the internal translation initiation region of encephalomyocarditis virus RNA
8. Pyrimidine tract binding protein strongly stimulates in vitro encephalomyocarditis virus RNA translation at the level of preinitiation complex formation
9. Growth-dependent and growth-independent translation of messengers for heterogeneous nuclear ribonucleo-proteins
10. Translational inhibition in vitro of human papillomavirus type 16 L2 mRNA mediated through interaction with heterogenous ribonucleoprotein K and poly(rC)-binding proteins 1 and 2
11. Internal initiation of translation directed by the 5'-untranslated region of the mRNA for eIF4G, a factor involved in the picornavirus-induced switch from cap-dependent to internal initiation
12. Functional characterization of the internal ribosome entry site of eIF4G mRNA
13. Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns
14. hnRNP I, the polypyrimidine tract-binding protein: Distinct nuclear localization and association with hnRNAs
15. Characterization of cDNAs encoding the polypyrimidine tract-binding protein
16. Role of an inhibitory pyrimidine element and polypyrimidine tract binding protein in repression of a regulated alpha-tropomyosin exon
17. The use of antibodies to the polypyrimidine tract binding protein (PTB) to analyze the protein components that assemble on alternatively spliced pre-mRNAs that use distant branch points
18. Immunoglobulin heavy chain binding protein
19. Polypyrimidine tract-binding protein interacts with HnRNP L
20. A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein
21. The cellular polypeptide p57 (pyrimidine tract-binding protein) binds to multiple sites in the poliovirus 5' nontranslated region
22. Polypyrimidine-tract binding protein (PTB) is necessary, but not sufficient, for efficient internal initiation of translation of human rhinovirus-2 RNA
23. unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA
24. Cap-dependent and cap-independent independent translation by internal initiation of mRNAs in cell extracts prepared from Saccharomyces cerevisiae
25. A detailed kinetic analysis of the in vitro synthesis and processing of encephalomyocarditis virus products
26. Internal initiation of translation of picornavirus RNAs
27. Cap-dependent and cap-independent translation: Operational distinctions and mechanistic interpretations
28. Cap-independent translation of encephalomyocarditis virus RNA: Structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein
29. A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation
30. Initiation of protein synthesis by internal entry of ribosomes into the 5' non-translated region of encephalomyocarditis virus RNA in vivo
31. Cap-independent translation of picornavirus RNAs: Structure and function of the internal ribosomal entry site
32. PDGF2/c-sis mRNA Leader contains a differentiation-linked internal ribosomal entry site (D-IRES)
33. Direct evidence that polypyrimidine tract binding protein (PTB) is essential for internal initiation of translation of encephalomyocarditis virus RNA
34. La protein is required for efficient translation driven by encephalomyocarditis virus internal ribosomal entry site
35. Influences of mRNA secondary structure on initiation by eukaryotic ribosomes
36. The scanning model for translation: An update
37. Mammalian stress response: Induction of the glucose-regulated protein family
38. Biochemical characterization of the 94- and 78-kilodalton glucose-regulated proteins in hamster fibroblasts
39. Polypyrimidine tract-binding protein positively regulates inclusion of an alternative 3'-terminal exon
40. Interaction of a cellular 57-kilodalton protein with the internal translation initiation site of foot-and-mouth disease virus
41. Internal initiation of translation mediated by the 5' leader of a cellular mRNA
42. A cellular protein that binds to the 5'-noncoding region of poliovirus RNA: Implications for internal translation initiation
43. La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate
44. Signal sequences that target nuclear import and nuclear export of pre-mRNA-binding proteins
45. Immunoglobulin binding protein (Bip) function is required to protect cells from endoplasmic reticulum stress but is not required for the secretion of selective proteins
46. An Hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein
47. Alternative translation of the proto-oncogene c-myc by an internal ribosome entry site
48. A novel rapid assay for chloramphenicol acetyltransferase gene expression
49. Porcine polypyrimidine tract-binding protein stimulates translation initiation at the internal ribosome entry site of foot-and-mouth-disease virus
50. Homeotic gene Antennapedia mRNA contains 5'-noncoding sequences that confer translational initiation by internal ribosome binding
51. Determination of functional domains in polypyrimidine tract-binding protein
52. Evidence for role of glycoprotein carbohydrates in membrane transport: Specific inhibition by tunicamycin
53. Protease required for processing picornaviral coat protein resides in the viral replicase gene
54. Speculations on the functions of the major heat shock and glucose-regulated proteins
55. Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA
56. Infection with paramyxoviruses stimulates synthesis of cellular polypeptides that are also stimulated in cells transformed by Rous sarcoma virus or deprived of glucose
57. Multiple RRMs contribute to RNA binding specificity and affinity for polypyrimidine tract binding protein
58. Brefeldin A, thapsigargin, and AIF4-stimulate the accumulation of GRP78 mRNA in a cycloheximide dependent manner, whilst induction by hypoxia is independent of protein synthesis
59. Stimulation of GRP78 gene transcription by phorbol ester and cAMP in GH3 pituitary cells. The accommodation of protein synthesis to chronic deprivation of intracellular sequestered calcium
60. Translation of glucose-regulated protein 78/immunoglobulin heavy-chain binding protein mRNA is increased in poliovirus-infected cells at a time when cap-dependent translation of cellular mRNAs is inhibited
61. Eukaryotic initiation factors-4E and -4F stimulate 5' cap-dependent as well as internal initiation of protein synthesis
62. Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins
63. Polypyrimidine tract binding protein functions as a repressor to regulate alternative splicing of alpha-actinin mutally exclusive exons
64. 78-kilodalton glucose-regulated protein is induced in Rous sarcoma virus-transformed cells independently of glucose deprivation
65. C-Myc 5' untranslated region contains an internal ribosome entry segment
66. Internal translation initiation on poliovirus RNA: Further characterization of La function in poliovirus translation in vitro
67. General RNA binding proteins render translation cap dependent
68. The human insulin-like growth factor II leader 1 contains an internal ribosomal entry site
69. Internal ribosome entry site within hepatitis C virus RNA
70. Relationship between defective mouse mammary tumor virus envelope glycoprotein synthesis and GRP78 synthesis in glucocorticoid-treated mouse lymphoma cells. Evidence for translational control of GRP78 synthesis
71. Alternative translation of human fibroblast growth factor 2 mRNA occurs by internal entry of ribosomes
72. The mammalian heat shock (or stress) response: A cellular defense mechanism
73. 2+-ionophore-regulated proteins
74. Inhibition of protein synthesis and early protein processing by thapsigargin in cultured cells
75. Selective stimulation of the synthesis of an 80,000-dalton protein by calcium ionophores
76. Location of the internal ribosome entry site in the 5' non-coding region of the immunoglobulin heavy-chain binding protein (BiP) mRNA: Evidence for specific RNA-protein interactions
77. Algorithms and thermodynamics for RNA secondary structure prediction: A practical guide