3-Deoxyclocinnamox: The first high-affinity, nonpeptide μ-opioid antagonist lacking a phenolic hydroxyl group

Journal of Medicinal Chemistry

Volumn 43, Issue 17, 2000, Pages 3348-3350

  Derrick, I ^a   Neilan, C L ^b   Andes, J ^b   Husbands, S M ^a   Woods, J H ^b   Traynor, J R ^b   Lewis, J W ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 DEOXYCLOCINNAMOX; CLOCINNAMOX; MORPHINAN DERIVATIVE; MORPHINONE; MU OPIATE RECEPTOR ANTAGONIST; PHENOL; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; MONKEY; NONHUMAN; RECEPTOR AFFINITY;

ANIMALS; BINDING, COMPETITIVE; BRAIN; CLONING, MOLECULAR; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HAPLORHINI; HUMANS; MORPHINE DERIVATIVES; NARCOTIC ANTAGONISTS; RADIOLIGAND ASSAY; RATS; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; TUMOR CELLS, CULTURED;

EID: 0034710723     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0009641     Document Type: Article

References (14)

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