Antinociceptive effects of calcitonin gene-related peptide injected into periaqueductal grey of rats with mononeuropathy

Brain Research

Volumn 859, Issue 2, 2000, Pages 358-360

  Xu, Shi Lian ^a   Lundeberg, Thomas ^b   Yu, Long Chuan ^a,b  

^a PEKING UNIVERSITY   (China)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Calcitonin gene related peptide (CGRP); CGRP8 37; Hindpaw withdrawal latency; Periaqueductal grey (PAG); Sciatic nerve ligation

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CALCITONIN GENE RELATED PEPTIDE[8-37];

ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ADMINISTRATION; MALE; MONONEUROPATHY; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT;

ANALGESIA; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; MALE; MONONEUROPATHIES; NOCICEPTORS; PAIN; PAIN MEASUREMENT; PERIAQUEDUCTAL GRAY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0034708547     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)02407-5     Document Type: Article

References (12)

1. N. Attal, F. Jazat, V. Kayser, G. Gilbaud, Further evidence for pain related behaviors in a model of unilateral peripheral neuropathy, Pain 41 (1990) 235-251.
2. G.J. Bennett, Y.K. Xie, A peripheral neuropathy in rat that produces disorders of pain sensation like those seen in man, Pain 33 (1988) 87-108.
3. S. Candeletti, S. Ferri, Antinociceptive profile of intracerebroventricular salmon calcitonin and calcitonin gene-related peptide in the mouse formalin test, Neuropeptides 17 (1990) 93-98.
4. R.A. Cridland, J.L. Henry, Intrathecal administration of CGRP in the rat attenuates a facilitation of the tail flick reflex induced by either substance P or noxious cutaneous stimulation, Neurosci. Lett. 102 (1989) 241-246.
5. H.L. Fields, A.I. Basbaum, Central nervous system mechanisms of pain modulation, in: P.D. Wall, R. Melzack (Eds.), Textbook of Pain, 3rd edn., Churchill Livingstone, Edinburgh, 1994, pp. 243-257.
6. C.A. Miggi, T. Chiba, S. Giuliani, Human α-calcitonin gene-related peptide-(8-37) as an antagonist of exogenous and endogenous calcitonin gene-related peptide, Eur. J. Pharmacol. 192 (1991) 85-88.
7. M.J. Millan, The induction of pain: an integrative review, Prog. Neurobiol. 57 (1999) 1-164.
8. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, 2nd edn., Academic Press, Sydney, 1986.
9. A. Pecile, F. Guidobono, C. Netti, Calcitonin gene-related peptide: antinociceptive activity in rats, comparison with calcitonin, Regul. Pept. 18 (1987) 189-199.
10. G.S.T. Smith, D. Savery, C. Marden, J.J.L. Costa, S. Averill, J.V. Priestley, M. Rattray, Distribution of messenger RNAs encoding enkephalin, substance P, somatostatin, galanin, vasoactive Y, and calcitonin gene-related peptide in the midbrain periaqueductal grey in the rat, J. Comp. Neurol. 350 (1994) 23-40.
11. L.C. Yu, P. Hansson, T. Lundeberg, The calcitonin gene-related peptide antagonist CGRP8-37 increases the latency to withdrawal responses bilaterally in rats with unilateral experimental mononeuropathy, an effect partly reversed by naloxone, Neuroscience 71 (1996) 523-531.
12. L.C. Yu, P. Hansson, S. Lundeberg, T. Lundeberg, Effects of calcitonin gene-related peptide-(8-37) on withdrawal responses in rats with inflammation, Eur. J. Pharmacol. 347 (1998) 275-282.