Binding properties of [3H]gacyclidine (cis(pip/me)-1-[1-(2-thienyl)-2-methylcyclohexyl]piperidine) enantiomers in the rat central nervous system

Brain Research

Volumn 859, Issue 2, 2000, Pages 177-192

  Hirbec, Hélène ^a   Teilhac, Jean René ^a   Kamenka, Jean Marc ^b   Privat, Alain ^a   Vignon, Jacques ^a  

^a INSERM   (France)

^b Centre National de la Recherche Scientifique   (France)

Author keywords

Gacyclidine; GK11; Neuroprotection; NMDA receptor; Phencyclidine receptor

Indexed keywords

1 [4 (2 FURYL)TETRAHYDRO 4H PYRANYL]PIPERIDINE; 1 [4 (2 FURYL)TETRAHYDRO 4H THIOPYRANYL]PIPERIDINE; 4 PHOSPHONOMETHYLPIPECOLIC ACID; DIZOCILPINE; GACYCLIDINE; GLUTAMIC ACID; GLYCINE; JH 6; JH 68; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROPROTECTIVE AGENT; NS 1102; PIPERIDINE DERIVATIVE; RADIOLIGAND; RE 084; TENOCYCLIDINE; TRITIUM; UNCLASSIFIED DRUG; CYCLOHEXANE DERIVATIVE; CYCLOHEXENE DERIVATIVE; DIAGNOSTIC AGENT;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BRAIN HOMOGENATE; BRAIN REGION; CELLULAR DISTRIBUTION; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CONTROLLED STUDY; DOSE RESPONSE; DRUG RECEPTOR BINDING; ENANTIOMER; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; SPINAL CORD; TELENCEPHALON; ANIMAL; BINDING COMPETITION; BINDING SITE; CELL FRACTIONATION; CHEMISTRY; CYTOLOGY; DRUG EFFECT; FOREBRAIN; KINETICS; METABOLISM; RADIOASSAY; STEREOISOMERISM; WISTAR RAT;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CYCLOHEXANES; CYCLOHEXENES; KINETICS; MALE; NEUROPROTECTIVE AGENTS; PIPERIDINES; PROSENCEPHALON; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; SPINAL CORD; STEREOISOMERISM; SUBCELLULAR FRACTIONS; TRITIUM;

EID: 0034708267     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)02420-8     Document Type: Article

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