Purification and characterization of diquat (1,1'-ethylene-2,2'-dipyridylium)- metabolizing enzyme from paraquat-resistant rat liver cytosol

Toxicology

Volumn 154, Issue 1-3, 2000, Pages 55-66

  Nakajima, Makoto ^a   Nagao, Masataka ^b   Iwasa, Mineo ^b   Monma Ohtaki, Jun ^b   Maeno, Yoshitaka ^b   Koyama, Hiroyoshi ^b   Seko Nakamura, Yoshimi ^b   Isobe, Ichiro ^b   Takatori, Takehiko ^c  

^a UNIVERSITY OF TOKYO   (Japan)

^b NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

^c NATIONAL RESEARCH INSTITUTE OF POLICE SCIENCE   (Japan)

Author keywords

Diquat metabolizing enzyme; Paraquat; Purification; Rat liver cytosol; Resistance

Indexed keywords

DIQUAT; DIQUAT METABOLIZING ENZYME; LIVER ENZYME; PARAQUAT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME PURIFICATION; FEMALE; ISOELECTRIC POINT; LIVER CYTOSOL; LIVER MICROSOME; MALE; MOLECULAR WEIGHT; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; TOXICOKINETICS;

ANIMALS; BLOTTING, WESTERN; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, AGAROSE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOSOL; DIQUAT; DRUG RESISTANCE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; FIBRIN; FIBRINOGEN; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HERBICIDES; ISOELECTRIC FOCUSING; KINETICS; LIVER; MALE; PARAQUAT; PROTEINS; RATS; RATS, WISTAR;

ANIMALIA; RAPHIA FRATER; RATTUS NORVEGICUS;

EID: 0034706925     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(00)00299-7     Document Type: Article

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