Site-specific DNA hypomethylation permits expression of the IRBP gene

Brain Research

Volumn 887, Issue 1, 2000, Pages 211-221

  Boatright, Jeffrey H ^a   Nickerson, John M ^a   Borst, Diane E ^b  

^a EMORY EYE CENTER   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

DNA methylation; Gene expression regulation; Interphotoreceptor retinoid binding protein; Photoreceptor; Pineal gland; Retina

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; DINUCLEOTIDE; NUCLEAR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATTLE; DNA METHYLATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENE STRUCTURE; GENE TARGETING; GENETIC TRANSCRIPTION; METHYLATION; MOUSE; NONHUMAN; PHOTORECEPTOR; PINEAL BODY; PINEALOCYTE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; RETINA CELL; SIMIAN VIRUS 40; SOUTHERN BLOTTING; STRUCTURE ACTIVITY RELATION;

ANIMALS; CATTLE; CELLS, CULTURED; CHICK EMBRYO; DNA METHYLATION; EYE PROTEINS; GENE EXPRESSION REGULATION; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; PHOTORECEPTORS; PINEAL GLAND; PROMOTER REGIONS (GENETICS); RETINA; RETINAL GANGLION CELLS; RETINOL-BINDING PROTEINS;

EID: 0034704328     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02990-5     Document Type: Article

References (74)

1. Hypomethylation of the interphotoreceptor retinoid-binding protein (IRBP) promoter and first exon is linked to expression of the gene
2. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
3. The immunoglobulin lambda light chain enhancer consists of three modules which synergize in activation of transcription
4. Methylation mapping of the IRBP 5′ flanking region
5. A major cis activator of the IRBP gene contains CRX-binding and Ret-1/PCE-I elements
6. The 5′ flanking regions of mouse IRBP and arrestin have promoter activity in primary embryonic chicken retina cell cultures
7. A single cis-acting element in a short promoter segment of the gene encoding the interphotoreceptor retinoid-binding protein confers tissue-specific expression
8. DNA methylation of the IRBP promoter
9. The isolation of a gene encoding interphotoreceptor retinoid-binding protein
10. DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein
11. Repression of genes by DNA methylation depends on CpG density and promoter strength: Evidence for involvement of a methyl-CpG binding protein
12. Immunocytochemical localization of two retinoid-binding proteins in vertebrate retina
13. T cell receptor V beta 8.2 gene germ-line transcription: An early event of lymphocyte differentiation
14. Promotion of the release of 11-cis-retinal from cultured retinal pigment epithelium by interphotoreceptor retinoid-binding protein
15. Differential effect of the rd mutation on rods and cones in the mouse retina
16. Rhodopsin, 11-cis vitamin A, and interstitial retinol-binding prote (IRBP) during retinal development in normal and rd mutant mice
17. DNA methylation and gene activity
18. Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes
19. High sensitivity mapping of methylated cytosines
20. Role of DNA methylation in the regulation of transcription
21. Effect of DNA methylation on the binding of vertebrate and plant, proteins to DNA
22. A novel Alu-like element rearranged in the dystrophin gene causes a splicing mutation in a family with X-linked dilated cardiomyopathy
23. Developmental changes of DNA methylation pattern of embryonic chick pepsinogen gene
24. Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation
25. CpG methylation has differential effects on the binding of YY1 and ETS proteins to the bi-directional promoter of the Surf-1 and Surf-2 genes
26. CpG methylation and the binding of YY1 and ETS proteins to the Surf-1/Surf-2 bidirectional promoter
27. Interaction of protein with DNA in vitro
28. Analysis of cell specific transcriptionl of the human cone transducin alpha subunit gene
29. CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation
30. Relationships between chromatin organization and DNA methylation in determining gene expression
31. Repression of transient expression by DNA methylation in transcribed regions of reporter genes introduced into cultured human cells
32. Tissue-specific transcriptional regulation of human leukosialin (CD43) gene is achieved by DNA methylation
33. Light deprivation profoundly affects gene expression of interphotoreceptor retinoid-binding protein in the mouse eye
34. Using proteases to avoid false identification of DNA-protein complexes in gel shift assays
35. Novel use of a polymeric chromophore in detecting sequence-specific DNA-binding proteins
36. Early onset photoreceptor abnormalities induced by targeted disruption of the interphotoreceptor retinoid-binding protein gene
37. Timing of interphotoreceptor retinoid-binding protein (IRBP) gene expression and hypomethylation in developing mouse retina
38. CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements
39. DNA methylation: Regulation of gene expression and role in the immune system
40. The topology of the promoter of RNA polymerase II- and III-transcribed genes is modified by the methylation of 5′-CG-3′ dinucleotides
41. A novel rapid assay for chloramphenicol acetyltransferase gene expression
42. DNA methylation and chromatin modification
43. Site-specific methylation of the rat prolactin and growth hormone promoters correlates with gene expression
44. CpG methylation represses the activity of the rat prolactin promoter in rat GH3 pituitary cell lines
45. Methylation of the promoter region may be involved in tissue-specific expression of the mouse terminal deoxynucleotidyl transferase gene
46. Interphotoreceptor retinoid-binding protein: Role in the delivery of retinol to the pigment epithelium
47. Interphotoreceptor retinoid-binding protein promotes rhodopsin regeneration in toad photoreceptors
48. Tissue-specific methylation occurs in the essential promoter element of the tyrosine hydroxylase gene
49. Kinetics of visual pigment regeneration in excised mouse eyes and in mice with a targeted disruption of the gene encoding interphotoreceptor retinoid-binding protein or arrestin
50. Detection of interphotoreceptor retinoid binding protein (IRBP) mRNA in human and cone-dominant squirrel retinas by in situ hybridization
51. Zebrafish interphotoreceptor retinoid-binding protein: Differential circadian expression among cone subtypes
52. CpG methylation, chromatin structure and gene silencing - A three-way connection
53. Genomic footprinting and sequencing of human beta-globin locus
54. State of methylation of the human osteocalcin gene in bone-derived and other types of cells
55. Comparative light and electron microscopic study of retinal histogenesis in normal and rd mutant mice
56. Cis-elements required for the demethylation of the mouse M-lysozyme downstream enhancer
57. DNA methylation represses transcription in vivo
58. DNA-methylation of the e-selectin promoter represses NF-kappaB transactivation
59. Detection of specific sequences among DNA fragments separated by gel electrophoresis
60. Immunoglobulin gene transcription
61. Effects of DNA methylation on DNA-binding proteins and gene expression
62. Synthesis and stability of retinal photoreceptor mRNAs are coordinately regulated during bovine fetal development
63. Reduction with age in methylcytosine in the promoter region -224 approximately -101 of the amyloid precursor protein gene in autopsy human cortex
64. Decrease with age in methylcytosines in the promoter region of receptor for advanced glycated end products (RAGE) gene in autopsy human cortex
65. Methylation of an ETS site in the intron enhancer of the keratin 18 gene participates in tissue-specific repression
66. A developmental study of interphotoreceptor retinoid-binding protein (IRBP) in single and double homozygous rd and rds mutant mouse retinae
67. Retinal photoreceptor neurons and pinealocytes accumulate mRNA for interphotoreceptor retinoid-binding protein (IRBP)
68. Expression of transfected genes by differentiated, postmitotic neurons and photoreceptors in primary cell cultures
69. Vitamin A receptors: Multiple species in retina and brain and possible compartmentalization in retinal photoreceptors
70. An estrogen-dependent demethylation at the 5′ end of the chicken vitellogenin gene is independent of DNA synthesis
71. Gene methylation patterns and expression
72. Regulation of the rat thyrotropin receptor gene by the methylation-sensitive transcription factor GA-binding protein