Dissection of binding energy with native and ligand-bound protein stabilities: Determining the affinity of ultratight-binding inhibitors of HIV-1 protease and its drug-resistance mutants [14]

Journal of the American Chemical Society

Volumn 122, Issue 46, 2000, Pages 11533-11534

  Xie, D ^a   Gulnik, S ^a   Erickson, J W ^a  

^a Tibotec Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE; VIRUS ENZYME;

BINDING AFFINITY; DATA ANALYSIS; DENATURATION; ENERGY; ENZYME ASSAY; HUMAN IMMUNODEFICIENCY VIRUS 1; LETTER; PROTEIN BINDING; PROTEIN STABILITY; SIGNAL NOISE RATIO; TITRIMETRY;

EID: 0034703701     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja003230m     Document Type: Letter

References (20)