Increased peripheral benzodiazepine binding sites and pentraxin 3 expression in the spinal cord during EAE: Relation to inflammatory cytokines and modulation by dexamethasone and rolipram

Journal of Neuroimmunology

Volumn 109, Issue 2, 2000, Pages 105-111

  Agnello, Davide ^a   Carvelli, Lucia ^a   Muzio, Valeria ^a   Villa, Pia ^a,c   Bottazzi, Barbara ^a   Polentarutti, Nadia ^a   Mennini, Tiziana ^a   Mantovani, Alberto ^a,b   Ghezzi, Pietro ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c CNR   (Italy)

Author keywords

Dexamethasone; Experimental autoimmune encephalomyelitis; Interleukin 6; Multiple sclerosis; Pentraxin 3; Peripheral type benzodiazepine receptor; PK11195; Rolipram; Tumor necrosis factor

Indexed keywords

BENZODIAZEPINE; BENZODIAZEPINE RECEPTOR; CYTOKINE; DEXAMETHASONE; GENE PRODUCT; INTERLEUKIN 6; MESSENGER RNA; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; PENTRAXIN 3; ROLIPRAM; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; FEMALE; GENE EXPRESSION; IMMUNOMODULATION; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; SPINAL CORD; TREATMENT OUTCOME;

AMYLOID P COMPONENT; ANIMAL; ANTINEOPLASTIC AGENTS; BENZODIAZEPINES; BINDING SITES; C-REACTIVE PROTEIN; DEXAMETHASONE; ENCEPHALOMYELITIS, EXPERIMENTAL AUTOIMMUNE; FEMALE; GENE EXPRESSION; GLUCOCORTICOIDS, SYNTHETIC; INTERLEUKIN-6; ISOQUINOLINES; KINETICS; MULTIPLE SCLEROSIS; PHOSPHODIESTERASE INHIBITORS; RADIOLIGAND ASSAY; RATS; RATS, INBRED LEW; RECEPTORS, GABA-A; RNA, MESSENGER; ROLIPRAM; SPINAL CORD; SUPPORT, NON-U.S. GOV'T; TRITIUM; TUMOR NECROSIS FACTOR;

EID: 0034703184     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(00)00279-4     Document Type: Article

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