Huperzine P, a novel lycopodium alkaloid from Huperzia serrata

Tetrahedron Letters

Volumn 41, Issue 30, 2000, Pages 5733-5736

  Tan, Chang Heng ^a   Jiang, Shan Hao ^a   Zhu, Da Yuan ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Huperzia serrata; Huperzine P; Lycopodium alkaloid; Natural products

Indexed keywords

ALKALOID; HUPERZINE P; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG ISOLATION; DRUG STRUCTURE; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; MEDICINAL PLANT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PLANT; X RAY CRYSTALLOGRAPHY;

HUPERZIA SERRATA; LYCOPODIUM;

EID: 0034702587     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)00893-5     Document Type: Article

References (10)

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2. Ayer, W. A.; Trifonov, L. S. In The Alkaloids, Vol. 45; Brossi, A., Ed.; Academic Press: New York, 1994; pp. 233.
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4. Zhang, R.-W.; Tang, X.-C.; Han, Y.-Y.; Sang, G.-W.; Zhang, Y.-D.; Ma, Y.-X.; Zhang, C.-L.; Yang, R.-M. Acta Pharmacol. Sin. 1991, 12, 250.
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8. Compound 3 was implied to probably be an artifact of phlegmariunine A upon basic treatment in Ref. 7. During this study, we did not find this to be the case, so proving 3 to be a natural product.
9. +] (97), 260 (22), 246 (9), 232 (11), 205 (22), 188 (21), 176 (14), 150 (100), 122 (47).
10. -3. The final R value was 0.045 for 1822 reflection.