A practical process for polymer-supported synthesis

Tetrahedron Letters

Volumn 41, Issue 30, 2000, Pages 5673-5677

  Quiclet Sire, Béatrice ^a   Wilczewska, Agnieszka ^a   Zard, Samir Z ^a,b  

^a INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

^b LABORATOIRE DE SYNTHÈSE ORGANIQUE   (France)

Author keywords

Oligomers; Radicals; Supported reactions; Xanthates

Indexed keywords

POLYMER;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; COMPLEX FORMATION; REACTION ANALYSIS; STRUCTURE ANALYSIS; SYNTHESIS;

EID: 0034702558     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)00886-8     Document Type: Article

References (9)

1. (a) Obrecht, D.; Villalgordo, J. M. Solid-Supported Combinatorial and Parallel Synthesis of Small-Molecular-Weight Compound Libraries; Pergamon Press: Oxford, 1998.
2. (a) Gravert, D. J.; Janda, K. D. Chem. Rev. 1997, 97, 489-509.
3. Enholm, E. J.; Gallagher, M. E.; Moran, K. M.; Lombardi, J. S.; Schulte, J. P. Org. Lett. 1999, 1, 689-691.
4. For a review of our work on xanthates, see: Zard, S. Z. Angew. Chem., Int. Ed. Engl. 1997, 36, 672-685.
5. Charmot, D.; Corpart, P.; Michelet, D.; Zard, S. Z.; Biadatti, T. WO 9858974 Priority June 23, 1997 (to Rhodia Chimie). This polymerisation process has been named MADIX (for MAcromolecular Design via Interchange of Xanthate). A mechanistically similar system using dithioesters was concomittantly developed by CSIRO chemists and termed RAFT: Chiefari, J.; Chong, Y. K.; Ercole, F.; Kristina, J.; Jeffrey, J.; Le, T. P. T.; Mayadunne, R. T. A.; Meijs, G. F.; Moad, G.; Moad, C. L.; Rizzardo, E.; Thang, S. H. Macromolecules 1998, 31, 5559-5561.
6. Hawker, C. J. Acc. Chem. Res. 1997, 30, 373-382.
7. (a) Boiteau, L.; Boivin, J.; Quiclet-Sire, B.; Saunier, J.-B.; Zard, S. Z. Tetrahedron 1998, 54, 2087-2098.
8. (b) Biadatti, T.; Quiclet-Sire, B.; Saunier, J.-B.; Zard, S. Z. Tetrahedron Lett. 1998, 39, 19-22.
9. London, J. D.; Shulman, N. J. Chem. Soc. 1938, 1618-1621.