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This cyclization approach is analogous to those used in the following: (a) Almansa, C.; Gomez, L. A.; Cavalcanti, F. L.; Rodriguez, R.; Carceller, E.; Bartroli, J.; Garcia-Rafanell, J.; Forn, J. J. Med. Chem. 1993, 36, 2121-2133.
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85037498529
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note
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-1), but no complexation was observed for 3·G. We have not attempted to fit these data to a multiequilibrium model, which in any event would be complicated by the absence of a precise dissociation constant for the CG base pair.
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