Rho GTPases: Integrating integrin signaling

Journal of Cell Biology

Volumn 150, Issue 4, 2000, Pages

  Ridley, Anne ^a,b  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; RHO FACTOR;

ENZYME ACTIVATION; ENZYME CONFORMATION; ENZYME LOCALIZATION; ENZYME REGULATION; NOTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

EID: 0034698754     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.150.4.F107     Document Type: Note

References (24)

1. Formation of stable microspikes containing actin and the 55 kDa actin bundling protein, fascin, is a consequence of cell adhesion to thrombospondin-1: Implications for the anti-adhesive activities of thrombospondin-1
2. Thrombospondin-1
3. Characterization of cell-matrix adhesion requirements for the formation of fascin microspikes
4. Stimulation of fascin microspikes by thrombospondin-1 is mediated by the GTPases Rac and Cdc42
5. Requirement for Rho in integrin signalling
6. The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells
7. Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK
8. Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes
9. Rho family proteins in cell adhesion and cell migration
10. Tools of the trade: Use of dominant-inhibitory mutants of Ras-family GTPases
11. The small GTP-binding protein Rho stimulates tyrosine phosphorylation of focal adhesion kinase, p130 and paxillin
12. Integrin signaling
13. Rho GTPases and the actin cytoskeleton
14. The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins
15. The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts
16. The tenascin-C knockout revisited
17. Rho, Rac and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
18. Activation of Rac and Cdc42 by integrins mediates cell spreading
19. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
20. Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase
21. Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior
22. Signaling from Ras to Rac and beyond: Not just a matter of GEFs
23. The DH protein family, exchange factors for Rho-like GTPases
24. Tenascin-C suppresses Rho activation