γ-Aminobutyric acid- and glycine-immunoreactive neurons postsynaptic to substance P-immunoreactive axon terminals in the superficial layers of the rat medullary dorsal horn

Neuroscience Letters

Volumn 288, Issue 3, 2000, Pages 187-190

  Wang, Dan ^a   Li, Yun Qing ^a   Li, Jin Lian ^a   Kaneko, Takeshi ^b   Nomura, Sakashi ^b   Mizuno, Noboru ^c  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b KYOTO UNIVERSITY   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Aminobutyric acid; Dorsal horn; Glycine; Immunohistochemistry; Pain; Rat; Spinal trigeminal nucleus caudalis; Substance P

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; GLYCINE; GLYCINE RECEPTOR; SUBSTANCE P;

ANIMAL TISSUE; ARTICLE; ELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MICROSCOPY; NERVE CELL; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; TRIGEMINAL NUCLEUS;

ANIMALS; EXCITATORY POSTSYNAPTIC POTENTIALS; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; GAMMA-AMINOBUTYRIC ACID; GLYCINE; IMMUNOHISTOCHEMISTRY; MALE; MEDULLA OBLONGATA; MICROSCOPY, ELECTRON; POSTERIOR HORN CELLS; PRESYNAPTIC TERMINALS; RATS; RATS, WISTAR; SUBSTANCE P; TRIGEMINAL CAUDAL NUCLEUS;

EID: 0034698487     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)01226-X     Document Type: Article

References (20)

1. Almond J.R., Westrum L.E., Henry M.A. Post-embedding immunogold labeling of gamma-aminobutyric acid in lamina II of the spinal trigeminal subnucleus pars caudalis: I. A qualitative study. Synapse. 24:1996;39-47.
2. Alvarez F.J., Kavookjian A.M., Light A.R. Synaptic interactions between GABA-immunoreactive profiles and the terminals of functionally defined myelinated nociceptors in the monkey and cat spinal cord. J. Neurosci. 12:1992;2901-2917.
3. Barber R.P., Vaughn J.E., Saito K., McLaughlin B.J., Roberts E. GABAergic terminals are presynaptic to primary afferent terminals in the substantia gelatinosa of the rat spinal cord. Brain Res. 141:1978;35-55.
4. Basbaum A.I., Glazer E.J., Oertel W. Immunoreactive glutamic acid decarboxylase in the trigeminal nucleus caudalis of the cat: a light and electron-microscopic analysis. Somatosens. Res. 4:1986;77-94.
5. Carlton S.M., Hargett G.L., Coggeshall R.E. Distribution of glycine-immunoreactive profiles in the monkey spinal cord: a light microscopic and ultrastructural study. J. Comp. Neurol. 371:1996;589-602.
6. Carlton S.M., Hayes E.S. Light microscopic and ultrastructural analysis of GABA-immunoreactive profiles in the monkey spinal cord. J. Comp. Neurol. 300:1990;162-182.
7. Carlton S.M., Westlund K.N., Zhang D., Willis W.D. GABA-immunoreactive terminals synapse on primate spinothalamic tract cells. J. Comp. Neurol. 322:1992;528-537.
8. DiFiglia M., Aronin N. Synaptic interactions between GABAergic neurons and trigeminothalamic cells in the rat trigeminal nucleus caudalis. Synapse. 6:1990;358-363.
9. Iliakis B., Anferson N.L., Irish P.S., Henry M.A., Westrum L.E. Electron microscopy of immunoreactivity patterns for glutamate and γ-aminobutyric acid in synaptic glomeruli of the feline spinal trigeminal nucleus (subnucleus caudalis). J. Comp. Neurol. 366:1996;465-477.
10. Li J.-L., Kaneko T., Nomura S., Li Y.-Q., Mizuno N. Association of serotonin-like immunoreactive axons with nociceptive projection neurons in the caudal spinal trigeminal nucleus of the rat. J. Comp. Neurol. 384:1997;127-141.
11. Li J.-L., Wang D., Kaneko T., Shigemoto R., Nomura S., Mizuno N. The relationship between neurokinin-1 receptor and substance P in the medullary dorsal horn. A light and electron microscopic immunohistochemical study in the rat. Neurosci. Res. 36:2000;327-334.
12. Magoul R., Onteniente B., Geffard M., Calas A. Anatomical distribution and ultrastructural organization of the GABAergic system in the rat spinal cord. An immunocytochemical study using anti-GABA antibodies. Neuroscience. 20:1987;1001-1009.
13. Matthews M.A., Hoffmann K.D., Hernandez T.V. Ulex europaeus agglutinin-I binding to dental primary afferent projections in the spinal trigeminal complex combined with double immunolabeling of substance P and GABA elements using peroxidase and colloidal gold. Somatosens. Motor Res. 6:1989;413-536.
14. Nakaya Y., Kaneko T., Shigemoto R., Nakanishi S., Mizuno N. Immunohistochemical localization of substance P receptor in the central nervous system of the adult rat. J. Comp. Neurol. 347:1994;249-274.
15. Priestley J.V., Somogyi P., Cuello A.C. Immunocytochemical localization of substance P in the spinal trigeminal nucleus of the rat: a light and electron microscopic study. J. Comp. Neurol. 211:1982;31-49.
16. Rampon C., Luppi P.H., Fort P., Peyron C., Jouvet M. Distribution of glycine-immunoreactive cell bodies and fibers in the rat brain. Neuroscience. 75:1996;737-755.
17. Tashiro T., Takahashi O., Satoda T., Matsushima R., Uemura-Sumi M., Mizuno N. Distribution of axons showing calcitonin gene-related peptide- and/or substance P-like immunoreactivity in the sensory trigeminal nuclei of the cat. Neurosci. Res. 11:1991;119-133.
18. Todd A.J. GABA and glycine in synaptic glomeruli of the rat spinal dorsal horn. Eur. J. Neurosci. 8:1996;2492-2498.
19. Todd A.J., Spike R.C. The localization of classical transmitters and neuropeptides within neurons in laminae I-III of the mammalian spinal dorsal horn. Prog. Neurobiol. 41:1993;609-645.
20. Todd A.J., Sullivan A.C. Light microscopic study of the coexistence of GABA-like and glycine-like immunoreactivities in the spinal cord of the rat. J. Comp. Neurol. 296:1990;496-505.