Emergence of genetic instability in children treated for leukemia

Science

Volumn 288, Issue 5465, 2000, Pages 514-517

  Finette, B A ^a   Homans, A C ^a   Albertini, R J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; T LYMPHOCYTE RECEPTOR;

ACUTE LYMPHOCYTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; CHILD; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; GENE REARRANGEMENT; GENETIC STABILITY; HUMAN; PRIORITY JOURNAL; REPORTER GENE; T LYMPHOCYTE;

ADOLESCENT; ADULT; ALLELES; ANTINEOPLASTIC AGENTS; CELL LINEAGE; CELL TRANSFORMATION, NEOPLASTIC; CHILD; CHILD, PRESCHOOL; CLONE CELLS; DRUG RESISTANCE, NEOPLASM; GENE REARRANGEMENT, BETA-CHAIN T-CELL ANTIGEN RECEPTOR; GENES, REPORTER; GENES, T-CELL RECEPTOR; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INFANT; LEUKEMIA, B-CELL, ACUTE; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; MUTATION; NEOPLASMS, SECOND PRIMARY; RECURRENCE; T-LYMPHOCYTES;

EID: 0034697113     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.288.5465.514     Document Type: Article

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31. Supported by National Institute of Child Health & Human Development grant 1R29HD35309, National Cancer Institute (NCI) grant 1K01CA77737, grant 6103-98 from the Leukemia Society of America, the Lake Champlain Cancer Research Organization, the Vermont Chapter of the American Cancer Society, the Art Ehrmann Cancer Fund and NCI grant P30CA22435 to the University of Vermont Cancer Center DNA Analysis Facility. We thank C-C. Duriex-Lu, H. Kendall, and J. Rivers for technical assistance; S. Billado for assistance with blood samples; and P. Vacek for statistical analyses.