Modeling the evolution of genetic architecture: A continuum of alleles model with pairwise A x A epistasis

Journal of Theoretical Biology

Volumn 203, Issue 2, 2000, Pages 163-175

  Wagner, Günter P ^a   Mezey, Jason ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; EPISTASIS; EVOLUTION; GENE MUTATION; GENOTYPE; HEREDITY; HUMAN; MATHEMATICAL MODEL; MOLECULAR INTERACTION; PHENOTYPE; PRIORITY JOURNAL;

EID: 0034696453     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1006/jtbi.2000.1074     Document Type: Article

References (37)

1. The schema theorem and the Price's theorem
2. Estimating the heritability by decomposing the genetic variance
3. The effect of an experimental bottleneck upon genetic variation in the house fly
4. Mathematical properties of mutation-selection models
5. Epistasis and its contribution to genetic variance components
6. Epistasis as a source of increased additive genetic variance at population bottlenecks
7. Quantitative trait loci for marine growth
8. Mutation-selection balance and metabolic control theory
9. An extension of the concept of partitioning hereditary variance for analysis of covariance among relatives when epistasis is present
10. Test of synergistic interactions among deleterious mutations in bacteria
11. The correlation between relatives on the supposition of Mendelian inheritance
12. Evolution and speciation on holey adaptive landscapes
13. On the evolution of premating isolation after a founder event
14. Rapid parapatric speciation on holey adaptive landscapes
15. Epistasis and pleiotropy as natural properties of transcriptional regulation
16. On the effect of founder events on epistatic genetic variance
17. Epistasis and the effect of founder events on the additive genetic variance
18. The molecular basis of dominance
19. Towards a general theory of adaptive walks on rugged landscapes
20. A stochastic model of genetic variability in quantitative characters
21. Effects of P element insertions on quantitative traits in Drosophila melanogaster
22. Polygenic mutation in Drosophila melanogasater: Estimates from divergence among inbred strains
23. Developmental models and polygenic characters
24. Quantitative genetics of butterfly wing color patterns
25. The evolution of canalization and the breaking of von Baer's laws: Modeling the evolution of development with epistasis
26. Gene effects on a quantitative trait: Two-locus epistatic effects measured at microsatellite markers and at estimated QTL
27. Population dependent Fourier decomposition of fitness landscapes over recombination spaces
28. Canalization: Genetic and developmental aspects
29. Does evolutionary plasticity evolve?
30. Multivariate mutation-selection balance with constrained pleiotropic effects
31. Complex adaptations and the evolution of evolvability
32. A population genetic theory of canalization
33. Genetic measurement theory of epistatic effects
34. Multiple fitness peaks and epistasis
35. Genetics of postmating reproductive isolation in animals