Detection of HuD transcripts by means of reverse transcriptase and polymerase chain reaction: Implications for the detection of minimal residual disease in patients with small cell lung cancer

Cancer Letters

Volumn 161, Issue 2, 2000, Pages 157-164

  Torà, Montserrat ^a   Barberá, Víctor M ^a,b   Real, F X ^a,c  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO DE ELCHE   (Spain)

^c INST MUNIC D INVESTIGACIO MEDICA   (Spain)

Author keywords

HuD; Minimal residual disease; Neuroblastoma; Reverse transcriptase polymerase chain reaction; Small cell lung cancer

Indexed keywords

PROTEIN; RNA;

ARTICLE; CONTROLLED STUDY; GENE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LUNG SMALL CELL CANCER; MINIMAL RESIDUAL DISEASE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR RECURRENCE;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; BLOTTING, SOUTHERN; BLOTTING, WESTERN; CARCINOMA, SMALL CELL; CASE-CONTROL STUDIES; CLONING, MOLECULAR; COLON; COLONIC NEOPLASMS; DNA PRIMERS; DNA, COMPLEMENTARY; HU PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGENS; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; LYMPHOCYTES; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEUROBLASTOMA; PANCREAS; PANCREATIC NEOPLASMS; POLYMERASE CHAIN REACTION; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA-BINDING PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TUMOR CELLS, CULTURED;

EID: 0034695186     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(00)00577-2     Document Type: Article

References (33)

1. Therapy of small cell lung cancer: A perspective on two decades of clinical research
2. Long-term survival in small-cell lung cancer: Posttreatment characteristics in patients surviving 5 to 18+ years - an analysis of 1,714 consecutive patients
3. The expression of the Hu (paraneoplastic encephalomyelitis/sensory neuronopathy) antigen in human normal and tumor tissues
4. HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal
5. Mutant alleles at the locus elav in Drosophila melanogaster lead to nervous system defects. A developmental-genetic analysis
6. A conserved family of elav-like genes in vertebrates
7. The locus elav of Drosophila melanogaster is expressed in neurons at all developmental stages
8. Hel-N1: An autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs
9. A hippocampal protein associated with paraneoplastic neurologic syndrome and small cell lung carcinoma
10. Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein
11. Neuronal antinuclear antibody in sensory neuronopathy from lung cancer
12. Cell surface expression of paraneoplastic encephalomyelitis/sensory neuronopathy-associated Hu antigens in small-cell lung cancers and neuroblastomas
13. Paraneoplastic encephalomyelitis antigens bind to the AU-rich elements of mRNA
14. New pancreas cancer cell lines that represent distinct stages of ductal differentiation
15. Normal human pancreas cultures display functional ductal characteristics
16. Detection of cancer micrometastases in lymph nodes by reverse transcriptase-polymerase chain reaction
17. Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction
18. High frequency of K-ras mutations in normal appearing lung tissues and sputum of patients with lung cancer
19. Detection of the (11;22)(q24;q12) translocation of Ewing's sarcoma and peripheral neuroectodermal tumor by reverse transcription polymerase chain reaction
20. Detection of tumour cells in peripheral blood and bone marrow from Ewing tumour patients by RT-PCR
21. The detection of disseminated tumor cells in bone marrow from colorectal cancer patients by a cytokeratin 20-specific nested reverse transcriptase polymerase chain reaction is related to the stage of disease
22. Putative markers for the detection of breast carcinoma cells in blood
23. Expression of prostate-specific antigen and prostate-specific membrane antigen transcripts in blood cells: Implications for the detection of hematogenous prostate cells and standardization
24. Increased analytical sensitivity of RT-PCR of PSA mRNA decreases diagnostic specificity of detection of prostatic cells in blood
25. Detection of micrometastases by cytokeratin 20 RT-PCR is limited due to stable background transcription in granulocytes
26. Identification of a novel cytokeratin 19 pseudogene that may interfere with reverse transcriptase-polymerase chain reaction assays used to detect micrometastatic tumor cells
27. A polymerase chain reaction-based semiquantitative assessment of malignant melanoma cells in peripheral blood
28. Reliability of reverse transcription-polymerase chain reaction (RT-PCR)-based assays for detection of circulating tumour cells: A quality assurance initiative of the EORTC Melanoma Cooperative Group
29. Hu neuronal proteins are expressed in proliferating neurogenic cells
30. A post-transcriptional regulatory mechanism restricts expression of the paraneoplastic cerebellar degeneration antigen cdr2 to immune privileged tissues
31. Detection and quantitation of circulating cancer cells in the peripheral blood of lung cancer patients
32. Detection and characterization of carcinoma cells in the blood