Functional complementation by wheat eIF2α in the yeast GCN2-mediated pathway

Biochemical and Biophysical Research Communications

Volumn 279, Issue 2, 2000, Pages 468-474

  Chang, L Y ^a   Yang, W Y ^a   Roth, D ^a  

^a UNIVERSITY OF WYOMING   (United States)

Author keywords

EIF2 phosphorylation; GCN2; Plant translation; Translational control

Indexed keywords

ARTICLE; CONTROLLED STUDY; EUKARYOTE; FUNGUS GROWTH; IMMUNOPRECIPITATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STRAIN DIFFERENCE; TRANSGENE; TRANSLATION INITIATION; TRANSLATION REGULATION; WHEAT; YEAST;

EID: 0034694829     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.3964     Document Type: Article

References (27)

1. Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells
2. Expression of a phosphorylation resistant eukaryotic initiation factor 2α subunit mitigates heat shock inhibition of protein synthesis
3. The double-stranded RNA-dependent protein kinase PKR: Structure and function
4. Met ternary complexes
5. Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast
6. Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2α kinase
7. Cloning and characterization of a cDNA encoding a protein synthesis initiation factor-2α (eIF2α) kinase from Drosophila melanogaster
8. Identification of a plant-encoded analog of PKR, the mammalian double-stranded RNA-dependent protein kinase
9. Phosphorylation of plant eukaryotic initiation factor 2 by the plant encoded double-stranded RNA-dependent protein kinase, pPKR, and inhibition of protein synthesis in vitro
10. Viroid-induced phosphorylation of a host protein related to a dsRNA-dependent protein kinase
11. Temporal regulation of tobacco mosaic virus-induced phosphorylation of a host encoded protein
12. Specific in vitro phosphorylation of plant eIF2α by eukaryotic elF2α kinase
13. Wheat germ initiation factor 2 (WG-eIF2) decreases the inhibition in protein synthesis and eIF2B activity of reticulocyte lysates mediated by eIF2α phosphorylation
14. Interaction of wheat germ translation initiation factor 2 with GDP and GTP
15. In vivo regulation of protein synthesis by phosphorylation of the α subunit of wheat eukaryotic initiation factor 2
16. Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2
17. Mammalian eukaryotic initiation factor 2α kinases functionally substitute for GCN2 in the GCN4 translational control mechanism of yeast
18. Regulation of protein kinase PKR by the vaccinia virus pseudosubstrate inhibitor K3L is dependent on residues conserved between the K3L protein and the PKR substrate eIF2α
19. Expression of vaccinia virus K3L protein in yeast inhibits eukaryotic initiation factor-2 kinase GCN2 and the general amino acid control pathway
20. Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: Role of complex formation and the E3 N-terminal domain
21. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics
22. Using GCN4 as a reporter of eIF2α phosphorylation and translational regulation in yeast
23. A hierarchy of transacting factors modulate translation of an activator of amino acid biosynthetic genes in yeast