Urinary excretion of 4-hydroxyamphetamine and amphetamine in male and female Sprague-Dawley and Dark Agouti rats following multiple doses of amphetamine

Toxicology Letters

Volumn 117, Issue 3, 2000, Pages 139-144

  Law, Michael Y L ^a   Moody, David E ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

Amphetamine hydroxylation; Dark Agouti rat; Multiple doses of amphetamine; P450 2D deficient

Indexed keywords

AMPHETAMINE; CYTOCHROME P450; HYDROXYAMPHETAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG TOXICITY; FEMALE; GENDER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; METABOLISM; NONHUMAN; PRIORITY JOURNAL; RAT; URINALYSIS; URINE PH;

AMPHETAMINE; ANIMALS; CENTRAL NERVOUS SYSTEM STIMULANTS; FEMALE; MALE; P-HYDROXYAMPHETAMINE; RATS; RATS, INBRED STRAINS; RATS, SPRAGUE-DAWLEY; SEX CHARACTERISTICS; SPECIES SPECIFICITY;

AGOUTI;

EID: 0034694148     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(00)00256-3     Document Type: Article

References (16)

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15. Molecular basis of the Dark Agouti rat drug oxidation polymorphism: importance of CYP2D1 and CYP2D2