Minisatellite mutation frequency in human sperm following radiotherapy

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 453, Issue 1, 2000, Pages 67-75

  May, Celia A ^a   Tamaki, Keiji ^a   Neumann, Rita ^a   Wilson, Gene ^b   Zagars, Gunar ^b   Pollack, Alan ^b   Dubrova, Yuri E ^a   Jeffreys, Alec J ^a   Meistrich, Marvin L ^b  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Germline mutation; Ionizing radiation; Minisatellite; Radiotherapy; Sperm

Indexed keywords

DNA MINISATELLITE;

ADULT; ARTICLE; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; GENE AMPLIFICATION; GERM LINE; HUMAN; HUMAN CELL; IONIZING RADIATION; MALE; MEIOSIS; MUTATION; MUTATION RATE; PEDIGREE; PRIORITY JOURNAL; RADIATION DOSE; SEMINOMA; SPERM; SPONTANEOUS MUTATION; TANDEM REPEAT;

ADULT; DNA; HUMAN; MALE; MIDDLE AGE; MINISATELLITE REPEATS; MUTATION; POLYMERASE CHAIN REACTION; RADIOTHERAPY; SEMINOMA; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0034692555     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(00)00085-3     Document Type: Article

References (35)

1. Jeffreys A.J., Royle N.J., Wilson V., Wong Z. Spontaneous mutation rates to new length alleles at tandem-repetitive hypervariable loci in human DNA. Nature. 332:1988;278-281.
2. Kelly R., Bulfield G., Collick A., Gibbs M., Jeffreys A.J. Characterization of a highly unstable mouse minisatellite locus: evidence for somatic mutation during early development. Genomics. 5:1989;844-856.
3. Dubrova Y.E., Jeffreys A.J., Malashenko A.M. Mouse minisatellite mutations induced by ionizing radiation. Nature Genet. 5:1993;92-94.
4. Fan Y.F., Wang Z., Sadamoto S., Ninomiya Y., Kotomura N., Kamiya K., Dohi K., Kominami R., Niwa O. Dose-response of radiation induction of a germline mutation at a hypervariable mouse minisatellite locus. Int. J. Radiat. Biol. 68:1995;177-183.
5. Dubrova Y.E., Plumb M., Brown J., Fennelly J., Bois P., Goodhead D., Jeffreys A.J. Stage specificity, dose response, and doubling dose for mouse minisatellite germ-line mutation induced by acute radiation. Proc. Natl. Acad. Sci. U. S. A. 95:1998a;6251-6255.
6. Dubrova Y.E., Plumb M., Brown J., Jeffreys A.J. Radiation-induced germline instability at minisatellite loci. Int. J. Radiat. Biol. 74:1998b;680-696.
7. Kodaira M., Satoh C., Hiyama K., Toyama K. Lack of effects of atomic bomb radiation on genetic instability of tandem-repetitive elements in human germ cells. Am. J. Hum. Genet. 57:1995;1275-1283.
8. Satoh C., Kodaira M. Effects of radiation on children. Nature. 383:1996;226.
9. Dubrova Y.E., Nesterov V.N., Krouchinsky N.G., Ostapenko V.A., Neumann R., Neil D.L., Jeffreys A.J. Human minisatellite mutation rate after the Chernobyl accident. Nature. 380:1996;683-686.
10. Dubrova Y.E., Nesterov V.N., Krouchinsky N.G., Ostapenko V.A., Vergnaud G., Giraudeau F., Buard J., Jeffreys A.J. Further evidence for elevated human minisatellite mutation rate in Belarus eight years after the Chernobyl accident. Mutat. Res. 381:1997;267-278.
11. Livshits L.A., Malyarchuk S.G., Luk'yanova E.M., Antipkin Y.G., Arabskaya L.P., Kravchenko S.A., Matsuka G.H., Petit E., Giraudeau F., Le Guen B., Vergnaud G. Heritable mutations at some minisatellite loci analysis in children of liquidators of Chernobyl accident consequences. Int. J. Radiat. Med. 1:1999;101-106.
12. Jeffreys A.J., Tamaki K., Macleod A., Monckton D.G., Neil D.L., Armour J.A.L. Complex gene conversion events in germline mutation at human minisatellites. Nature Genet. 6:1994;136-145.
13. May C.A., Jeffreys A.J., Armour J.A.L. Mutation rate heterogeneity and the generation of allele diversity at the human minisatellite MS205 (D16S309). Hum. Mol. Genet. 5:1996;1823-1833.
14. Buard J., Bourdet A., Yardley J., Dubrova Y., Jeffreys A.J. Influences of array size and homogeneity on minisatellite mutation. EMBO J. 17:1998;3495-3502.
15. Tamaki K., May C.A., Dubrova Y.E., Jeffreys A.J. Extremely complex repeat shuffling during germline mutation at human minisatellite B6.7. Hum. Mol. Genet. 8:1999;879-888.
16. Kimpton C.P., Hopwood R., Watson S.K., Gill P., Sullivan K. Cloning and characterization of novel single locus probes for forensic purposes. Adv. Forensic Haemogenetics. 4:1992;129-131.
17. Vergnaud G., Mariat D., Apiou F., Aurias A., Lathrop M., Lauthier V. The use of synthetic tandem repeats to isolate new VNTR loci: cloning of a human hypermutable sequence. Genomics. 11:1991;135-144.
18. Buard J., Vergnaud G. Complex recombination events at the hypervariable minisatellite CEB1 (D2S90). EMBO J. 13:1994;3203-3210.
19. Jacobsen K.D., Olsen D.R., Fosså K., Fosså S.D. External beam abdominal radiotherapy in patients with seminoma stage I: filed type, testicular dose, and spermatogenesis. Int. J. Radiat. Oncol. Biol. Phys. 38:1997;95-102.
20. Jeffreys A.J., Neumann R., Wilson V. Repeat unit sequence variation in minisatellites: a novel source of DNA polymorphism for studying variation and mutation by single molecule analysis. Cell. 60:1990;473-485.
21. Centola G.M., Keller J.W., Henzler M., Rubin P. Effect of low-dose testicular irradiation on sperm count and fertility in patients with testicular seminoma. J. Androl. 15:1994;608-613.
22. Meistrich M.L. Hormonal stimulation of the recovery of spermatogenesis following chemo- or radiotherapy. A.P.M.I.S. 10:1998;37-46.
23. Zheng N., Monckton D.G., Wilson G., Ramagli L., Siciliano M.J., Meistrich M.L. Mutation frequency of minisatellite repeat number changes in human sperm before and after mitoxantrone, vincristine, vinblastine and prednisone (NOVP) chemotherapy. Environ. Mol. Mutagen. 31:1998;61.
24. Armour J.A.L., Brinkworth M.H., Kamischke A. Direct analysis by small-pool PCR of MS205 minisatellite mutation rates in sperm after mutagenic therapies. Mutat. Res. 445:1999;73-80.
25. N. Zheng, D.G. Monckton, G. Wilson, F. Hagemeister, R. Chakraborty, T.H. Connor, M.J. Sicilano, M.L. Meistrich, Frequency of minisatellite repeat number changes at the MS205 locus in human sperm before and after cancer chemotherapy, Environ. Mol. Mutagen. (in press).
26. Bois P., Collick A., Brown J., Jeffreys A.J. Human minisatellite MS32 (D1S8) displays somatic but not germline instability in transgenic mice. Hum. Mol. Genet. 6:1997;1565-1571.
27. Bois P., Jeffreys A.J. Minisatellite instability and germline mutation. Cell Mol. Life Sci. 55:1999;1636-1648.
28. Jeffreys A.J., Neil D.L., Neumann R. Repeat instability at human minisatellites arising from meiotic recombination. EMBO J. 17:1998;4147-4157.
29. Adler I-D. Comparison of the duration of spermatogenesis between male rodents and humans. Mutat. Res. 352:1996;169-172.
30. L.A. Ries, B.F. Hankey, B.K. Edwards, U.S. Department of Health and Human Services, Cancer Statistics Review 1973-1987, Bethesda MD, 1991.
31. Dosmann M.A., Zagars G.K. Postorchiectomy radiotherapy for stages I and II testicular seminoma. Int. J. Radiat. Oncol. Biol. Phys. 26:1993;381-390.
32. Martin R.H., Hildebrand K., Yamamoto J., Rademaker A., Barnes M., Douglas G., Arthur K., Ringrose T., Brown I.S., Douglas G. A comparison of chromosomal aberrations induced by in vivo radiotherapy in human sperm and lymphocytes. Mutat. Res. 226:1989;21-30.
33. Byrne J., Rasmussen S.A., Steinhom S.C., Connelly R.R., Myers M.H., Lynch C.F., Flannery J., Austin D.F., Holmes F.F., Holmes G.E., Strong L.C., Mulvihill J.J. Genetic disease in offspring of long-term survivors of childhood and adolescent cancer. Am. J. Hum. Genet. 62:1998;45-52.
34. Dodds L., Marrett D.L., Tomkins D.J., Green B., Sherman G. Case-control study of congenital anomalies in children of cancer patients. Br. Med. J. 307:1993;164-168.
35. da Cunha M.F., Meistrich M.L., Haq M.M., Gordon L.A., Wyrobek A.J. Temporary effects of AMSA (4′-19-acridinylamino methanesulfon-meta-anisidide) chemotherapy on spermatogenesis. Cancer. 49:1982;2459-2462.