Diphenylene iodonium as an inhibitor for the hydrogenase complex of Rhodobacter capsulatus. Evidence for two distinct electron donor sites

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1459, Issue 1, 2000, Pages 169-178

  Magnani, Paola ^a   Doussiere, Jacques ^b   Lissolo, Thierry ^a  

^a UNIVERSITÉ DE SAVOIE   (France)

^b CEA GRENOBLE   (France)

Author keywords

Benzyl viologen; Diphenylene iodonium; Hydrogenase; Methylene blue; Rhodobacter capsulatus

Indexed keywords

BENZYLVIOLOGEN; DIPHENYLIODONIUM SALT; ENZYME INHIBITOR; HYDROGENASE; METHYLENE BLUE;

ARTICLE; ELECTRON; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; RHODOBACTER CAPSULATUS;

BENZYL VIOLOGEN; BINDING SITES; ELECTRON TRANSPORT; ENZYME INHIBITORS; HYDROGENASE; METHYLENE BLUE; MODELS, CHEMICAL; ONIUM COMPOUNDS; OXIDATION-REDUCTION; PROTEIN CONFORMATION; RHODOBACTER CAPSULATUS;

BACTERIA (MICROORGANISMS); PHOTOBACTERIA; RHODOBACTER CAPSULATUS; WOLINELLA SUCCINOGENES;

EID: 0034691749     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0005-2728(00)00145-6     Document Type: Article

References (27)

1. Gatley S.J., Sheratt S.A. The effect of diphenylene iodonium on mitochondrial reactions. Biochem. J. 158:1976;307-315.
2. Ragan C.I., Bloxham D.P. Specific labelling of a constituent polypeptide of bovine heart mitochondrial reduced nicotinamideadenine dinucleotide-ubiquinone reductase by the inhibitor diphenylene iodonium. Biochem. J. 163:1977;605-615.
3. Cross A.R., Jones O.T.G. The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Biochem. J. 237:1986;111-116.
4. Yea C.M., Cross A.A., Jones O.T.G. Biochem. J. 265:1990;95-100.
5. - generating oxidase of neutrophils by iodonium biphenyl in a cell free system: effect of the redox state of the oxidase complex. Biochem. Biophys. Res. Commun. 175:1991;143-151.
6. Doussiere J., Vignais P.M. Diphenylene iodonium as an inhibitor of the NADPH oxidase complex of bovine neutrophils. Eur. J. Biochem. 208:1992;61-71.
7. Battioni J.P., Dupré D., Delaforge M., Jaouen M., Mansuy D. J. Organomet. Chem. 358:1988;389-400.
8. Voordouw W.G. Evolution of hydrogenase genes. Adv. Inorg. Chem. 38:1992;397-422.
9. Wu L.F., Mandrand M.A. Microbial hydrogenases: primary structure, classification, signatures and phylogeny. FEMS Microbiol. Rev. 104:1993;243-270.
10. 2 uptake hydrogenase (hup) of Rhodobacter capsulatus. Mol. Gen. Genet. 214:1988;97-107.
11. Volbeda A., Charon M.H., Piras C., Hatchikian E.C., Frey M., Fontecilla-Camps J.C. Crystal structure of the nickel-iron hydrogenase from Desulfovibrio gigas. Nature. 373:1995;580-587.
12. Richaud P., Vignais P.M., Colbeau A., Uffen R.L., Cauvin B. Molecular biology studies of the uptake hydrogenase of Rhodobacter capsulatus and Rhodocyclus gelatinosus. FEMS Microbiol. Rev. 87:1990;413-418.
13. Cauvin B., Colbeau A., Vignais P.M. The hydrogenase structural operon in Rhodobacter capsulatus contains a third gene hupM necessary for the formation of a physiological competent hydrogenase. Mol. Microbiol. 5:1991;2517-2527.
14. Colbeau A., Richaud P., Toussaint B., Caballero F.J., Elster C., Delphin C., Smith R.L., Chalbert J., Vignais P.M. Organisation of the genes necessary for the hydrogenase expression in Rhodobacter capsulatus. Sequence analysis and identification of two hyp regulatory mutants. Mol. Microbiol. 8:1993;15-29.
15. Dröss F., Geisler V., Lenger R., Theis F., Krafft T., Fahrenholz F., Kojro E., Duchêne A., Tripier D., Juvenal K., Kröger A. The quinone-reactive [NiFe] hydrogenase of Wolinella succinogenes. Eur. J. Biochem. 206:1992;93-102.
16. Bernhard M., Benelli B., Hochkoeppler A., Zannoni D., Friedrich B. Functional and structural rôle of the cytochrome b subunit of the membrane bound hydrogenase complex of Alcaligenes eutrophus H16. Eur. J. Biochem. 248:1997;179-186.
17. Colbeau A., Vignais P.M. The membrane-bound hydrogenase of Rhodopseudomonas capsulata, stability and catalytic properties. Biochim. Biophys. Acta. 662:1981;271-284.
18. Stephenson M., Stickland L.H. Hydrogenase: a bacterial enzyme activating molecular hydrogen. The properties of the enzyme. Biochem. J. 25:1931;205-214.
19. Peck H.D. Jr., Gest H. A new procedure for the assay of bacterial hydrogenase. J. Bacteriol. 71:1956;70-80.
20. Lissolo T., Pulvin S., Thomas D. Reactivation of the hydrogenase from Desulfovibrio gigas by hydrogen. J. Biol. Chem. 259:1984;11725-11729.
21. H.I Segel, Enzyme Kinetics; John Wiley and Sons, New York, 1975.
22. Fauque G., Peck H.D. Jr., Huynh B.H., Berlier Y., Der Vartanian D.V., Teixeira M., Przybyla A.E., Lespinat P.A., Moura I., LeGall J. The tree classes of hydrogenases from sulfate-reducing bacteria of the genus Desulfovibrio. FEMS Microbiol. Rev. 54:1988;299-344.
23. Berlier Y.M., Fauque G., Lespinat P.A., Le Gall J. Activation, reduction and proton deuterium exchange reaction of the periplasmic hydrogenase from Desulfovibrio gigas in relation with the role of cytochrome c3. FEBS lett. 140:1982;185-188.
24. Fernandez V.M., Aguirre R., Hatchikian E.C. Reductive activation and redox properties of hydrogenase from Desulfovibrio gigas. Biochim. Biophys. Acta. 790:1984;1-7.
25. Schneider K., Schlegel H.G. Production of superoxide radicals by soluble hydrogenase from Alcaligenes eutrophus H16. Biochem J. 193:1981;99-107.
26. Berks B.C., Dudley M.P., Richardson D.J., Reilly A., Cavill A., Outen F., Ferguson S.T. Sequence analysis of subunits of the membrane-bound nitrate reductase from a denitrifying bacterium: the integral membrane subunit provides a prototype for the dihaem electron-carrying arm of a redox loop. Mol. Microbiol. 15:1995;319-331.
27. Teixeira M., Moura I., Xavier A.V., Huynh B.H., Der Vartanian D.V., Peck H.D. Jr., LeGall J., Moura J.J.G. Electron paramagnetic resonance studies on the mechanism of activation and the catalytic cycle of the nickel-containing hydrogenase from Desulfovibrio gigas. J. Biol. Chem. 260:1985;8942-8950.