Protection against measles virus-induced encephalitis by anti-mimotope antibodies: The role of antibody affinity

Virology

Volumn 272, Issue 1, 2000, Pages 98-105

  Olszewska, Wieslawa ^a   Obeid, Obeid E ^a   Steward, Michael W ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; VIRUS ANTIBODY; VIRUS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY AFFINITY; ANTIBODY RESPONSE; ARTICLE; CELLULAR IMMUNITY; IMMUNIZATION; INFECTION PREVENTION; LYMPHOCYTE PROLIFERATION; MEASLES VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRUS ENCEPHALITIS;

ANIMALIA; MEASLES VIRUS;

EID: 0034691093     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2000.0285     Document Type: Article

References (27)

1. Bachmann M. F., Kalinke U., Althage A., Freer G., Burkhart C., Roost H., Aguet M., Hengartner H., Zinkernagel R. M. The role of antibody concentration and avidity in antiviral protection. Science. 276:1997;2024-2027.
2. Chai S. K., Clavijo P., Tam J. P., Zavala F. Immunogenic properties of multiple antigen peptide systems containing defined T and B epitopes. J. Immunol. 149:1992;2385-2390.
3. Chargelegue D., Obeid O. E., Hsu S. C., Shaw M. D., Denbury A. N., Taylor G., Steward M. W. A peptide mimic of a protective epitope of respiratory syncytial virus selected from a combinatorial library induces virus-neutralizing antibodies and reduces viral load in vivo. J. Virol. 72:1998;2040-2046.
4. Chargelegue D., Stanley C. M., O'Toole C. M., Colvin B. T., Steward M. W. The affinity of IgG antibodies to gag p24 and p17 in HIV-1-infected patients correlates with disease progression. Clin. Exp. Immunol. 99:1995;175-181.
5. Croll A. D., Wilkinson M. F., Morris A. G. Gamma-interferon production by human low-density lymphocytes induced by T-cell mitogens. Immunology. 58:1986;641-646.
6. Defoort J. P., Nardelli B., Huang W., Ho D. D., Tam J. P. Macromolecular assemblage in the design of a synthetic AIDS vaccine. Proc. Natl. Acad. Sci. USA. 89:1992;3879-3883.
7. Folgori A., Tafi R., Meola A., Felici F., Galfre G., Cortese R., Monaci P., Nicosia A. A general strategy to identify mimotopes of pathological antigens using only random peptide libraries and human sera. EMBO J. 13:1994;2236-2243.
8. Giraudon P., Wild T. F. Correlation between epitopes on hemagglutinin of measles virus and biological activities: Passive protection by monoclonal antibodies is related to their hemagglutination inhibiting activity. Virology. 144:1985;46-58.
9. Ho P. C., Mutch D. A., Winkel K. D., Saul A. J., Jones G. L., Doran T. J., Rzepczyk C. M. Identification of two promiscuous T cell epitopes from tetanus toxin. Eur. J. Immunol. 20:1990;477-483.
10. Julius M. H., Simpson E., Herzenberg L. A. A rapid method for the isolation of functional thymus-derived mouse lymphocytes. Eur. J. Immunol. 10:1973;645-649.
11. Lairmore M. D., DiGeorge A. M., Conrad S. F., Trevino A. V., Lal R. B., Kaumaya P. T. Human T-lymphotropic virus type 1 peptides in chimeric and multivalent constructs with promiscuous T-cell epitopes enhance immunogenicity and overcome genetic restriction. J. Virol. 69:1995;6077-6089.
12. Lefrancois L. Protection against lethal viral infection by neutralizing and nonneutralizing monoclonal antibodies: Distinct mechanisms of action in vivo. J. Virol. 51:1984;208-214.
13. Obeid O. E., Partidos C. D., Howard C. R., Steward M. W. Protection against morbillivirus-induced encephalitis by immunization with a rationally designed synthetic peptide vaccine containing B- and T-cell epitopes from the fusion protein of measles virus. J. Virol. 69:1995;1420-1428.
14. Obeid O. E., Stanley C. M., Steward M. W. Immunological analysis of the protective responses to the chimeric synthetic peptide representing T- and B-cell epitopes from the fusion protein of measles virus. Virus Res. 42:1996;173-180.
15. Partidos C. D., Steward M. W. Prediction and identification of a T cell epitope in the fusion protein of measles virus immunodominant in mice and humans. J. Gen. Virol. 71:1990;2099-2105.
16. Partidos C., Stanley C., Steward M. The effect of orientation of epitopes on the immunogenicity of chimeric synthetic peptides representing measles virus protein sequences. Mol. Immunol. 29:1992a;651-658.
17. Partidos C., Stanley C., Steward M. The influence of orientation and number of copies of T and B cell epitopes on the specificity and affinity of antibodies induced by chimeric peptides. Eur. J. Immunol. 22:1992b;2675-2680.
18. Rath S., Stanley C. M., Steward M. W. An inhibition enzyme immunoassay for estimating relative antibody affinity and affinity heterogeneity. J. Immunol. Methods. 106:1988;245-249.
19. Schmaljohn A. L., Johnson E. D., Dalrymple J. M., Cole G. A. Non-neutralizing monoclonal antibodies can prevent lethal alphavirus encephalitis. Nature. 297:1982;70-72.
20. Steward M. W. Chronic immune complex disease in mice: The role of antibody affinity. Clin. Exp. Immunol. 38:1979;414-423.
21. Steward M. W., Chargelegue D. Overview. Antibody affinity: Measurement and biological significance. Weir D. M., Herzenberg L. A., Blackwell C. C. Handbook of Experimental Immunology. 1997;38.1 Blackwell, Oxford.
22. Steward M. W., Stanley C. M., Dimarchi R., Mulcahy G., Doel T. R. High-affinity antibody induced by immunization with a synthetic peptide is associated with protection of cattle against foot-and-mouth disease. Immunology. 72:1991;99-103.
23. Steward M. W., Stanley C. M., Obeid O. E. A mimotope from a solid-phase peptide library induces a measles virus-neutralizing and protective antibody response. J. Virol. 69:1995;7668-7673.
24. Stoute J. A., Ballou W. R., Kolodny N., Deal C. D., Wirtz R. A., Lindler L. E. Induction of humoral immune response against Plasmodium falciparum sporozoites by immunization with a synthetic peptide mimotope whose sequence was derived from screening a filamentous phage epitope library. Infect. Immun. 63:1995;934-939.
25. Tam J. P., Lu Y. A. Vaccine engineering: Enhancement of immunogenicity of synthetic peptide vaccines related to hepatitis in chemically defined models consisting of T- and B-cell epitopes. Proc. Natl. Acad. Sci. USA. 86:1989;9084-9088.
26. Watts C., Lanzavecchia A. Suppressive effect of antibody on processing of T cell epitopes. J. Exp. Med. 178:1993;1459-1463.
27. Watts C., West M. A., Reid P. A., Davidson H. W. Processing of immunoglobulin-associated antigen in B lymphocytes. Cold Spring Harbor Symp. Quant. Biol. 54:1989;345-352.