An investigation into the use of stepwise isothermal high sensitivity DSC as a means of detecting drug-excipient incompatibility

International Journal of Pharmaceutics

Volumn 199, Issue 2, 2000, Pages 141-150

  Wissing, Sylvia ^a   Craig, Duncan Q M ^a   Barker, Susan A ^b   Moore, William D ^b  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b Merck Sharp & Dohme Limited   (United Kingdom)

Author keywords

Aspirin; Compatibility; Differential scanning calorimetry; Excipient; Magnesium stearate; Stability; Stearic acid

Indexed keywords

ASCORBIC ACID; EXCIPIENT; MAGNESIUM STEARATE; STEARIC ACID;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DECOMPOSITION; DRUG DEGRADATION; DRUG INCOMPATIBILITY; DRUG MIXTURE; DRUG STABILITY; PRIORITY JOURNAL;

ASPIRIN; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG COMPOUNDING; EXCIPIENTS; MODELS, CHEMICAL; STEARIC ACIDS;

EID: 0034690129     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00380-X     Document Type: Article

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