1,3-Diarylcycloalkanopyrazoles and diphenyl hydrazides as selective inhibitors of cyclooxygenase-2

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 6, 2000, Pages 601-604

  Sui, Zhihua ^a   Guan, Jihua ^a   Ferro, Michael P ^a   McCoy, Kathy ^a   Wachter, Michael P ^a   Murray, William V ^a   Singer, Monica ^a   Steber, Michele ^a   Ritchie, Dave M ^a   Argentieri, Dennis C ^a  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DIPHENYLHYDRAZIDE DERIVATIVE; NONSTEROID ANTIINFLAMMATORY AGENT; PHENYL GROUP; PYRAZOLE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; ISOMER; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

AZIDES; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034689168     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00041-X     Document Type: Article

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