Precisely positioned nucleosomes are not essential for c-fos gene regulation in vivo

Gene

Volumn 255, Issue 2, 2000, Pages 169-184

  Fivaz, J ^a   Bassi, M C ^a   Price, M ^a   Pinaud, S ^a   Mirkovitch, J ^a  

^a SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

Author keywords

c fos; Chromatin; EBV episome; Nucleosome; Transcription

Indexed keywords

FORSKOLIN; PHORBOL 13 ACETATE 12 MYRISTATE; RNA POLYMERASE II;

ANIMAL CELL; ARTICLE; CELL CULTURE; CHROMATIN STRUCTURE; CONTROLLED STUDY; DELETION MUTANT; DNA SEQUENCE; EPISOME; EPSTEIN BARR VIRUS; GENE CONTROL; GENE TRANSFER; GENETIC STABILITY; IN VITRO STUDY; MOUSE; NONHUMAN; NUCLEOSOME; ONCOGENE C FOS; PRIORITY JOURNAL; REGULATOR GENE; TECHNIQUE; TRANSCRIPTION REGULATION; VIRUS VECTOR;

ANIMAL; CELL LINE; CHROMATIN; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; FORSKOLIN; GENE EXPRESSION REGULATION; HERPESVIRUS 4, HUMAN; HUMAN; IONOMYCIN; JURKAT CELLS; LUCIFERASE; MICE; NUCLEOSOMES; PLASMIDS; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-FOS; RECOMBINANT FUSION PROTEINS; RNA POLYMERASE II; SUPPORT, NON-U.S. GOV'T; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED;

EID: 0034687107     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(00)00339-5     Document Type: Article

References (31)

1. Albert T., Mautner J., Funk J.O., Hörtnagel K., Pullner A., Eick D. Nucleosomal structures of c-myc promoters with transcriptionally engaged RNA polymerase II. Mol. Cell. Biol. 17:1997;4363-4371.
2. Benjamin L.R., Gilmour D.S. Nucleosomes are not necessary for promoter-proximal pausing in vitro on the Drosophila hsp70 promoter. Nucleic Acids Res. 26:1998;1051-1055.
3. Bentley D.L., Groudine M. A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells. Nature. 321:1986;702-706.
4. Brown S.A., Imbalzano A.N., Kingston R.E. Activator-dependent regulation of transcriptional pausing on nucleosomal templates. Genes Dev. 10:1996;1470-1490.
5. Eick D., Bornkamm G.W. Transcriptional arrest within the first exon is a fast control mechanism in c-myc gene expression. Nucleic Acids Res. 14:1986;8331-8346.
6. 11 tract blocks nucleosome formation over the human neurofibromatosis type 1 (NF1)-Alu element. J. Biol. Chem. 271:1996;5819-5823.
7. Fivaz J., Bassi M.-C., Pinaud S., Richman L., Price M., Mirkovitch J. EBV-derived episomes to probe chromatin structure and gene expression in human cells. Methods Mol. Biol. 133:1999;167-182.
8. Fivaz J., Bassi M.-C., Pinaud S., Mirkovitch J. RNA polymerase II promoter-proximal pausing upregulates c-fos gene expression. Gene. 255:2000;185-194.
9. Fort P., Rech J., Piechaczyk M., Bonnieu A., Jeanteur P., Blanchard J.-M. Regulation of c-fos gene expression in hamster fibroblasts: initiation and elongation of transcription and mRNA degradation. Nucleic Acids Res. 15:1987;5657-5667.
10. Gong Q.H., McDowell J.C., Dean A. Essential role of NF-E2 in remodeling of chromatin structure and transcriptional activation of the epsilon-globin gene in vivo by 5′ hypersensitive site 2 of the beta-globin locus control region. Mol. Cell. Biol. 16:1996;6055-6064.
11. Herrera R.E., Shaw P.E., Nordheim A. Occupation of the c-fos serum response element in vivo by a multi-protein complex is unaltered by growth factor induction. Nature. 340:1989;68-70.
12. Herrera R.E., Nordheim A., Stewart A.F. Chromatin structure analysis of the human c-fos promoter reveals a centrally positioned nucleosome. Chromosoma. 106:1997;284-292.
13. Izban M.G., Luse D.S. Transcription on nucleosomal templates by RNA polymerase II in vitro: inhibition of elongation with enhancement of sequence-specific pausing. Genes Dev. 5:1991;683-696.
14. Janknecht R., Cahill M.A., Nordheim A. Signal integration at the c-fos promoter. Carcinogenesis. 16:1995;443-450.
15. Kontny E., Kvanta A., Fredholm B.B. Activation of protein kinase C and elevation of cAMP interact synergistically to raise c-Fos and AP-1 activity in Jurkat cells. Euro. J. Pharmacol. 227:1992;333-338.
16. Lu Q., Wallrath L.L., Elgin S.C. The role of a positioned nucleosome at the Drosophila melanogaster hsp26 promoter. EMBO J. 14:1995;4738-4746.
17. Margolskee R.F. Epstein-Barr virus based expression vectors. Curr. Top. Microbiol. Immunol. 158:1992;67-95.
18. Mirkovitch J., Decker T., Darnell J.E. Interferon induction of gene transcription analyzed by in vivo footprinting. Mol. Cell. Biol. 12:1992;1-9.
19. Morse R.H. Nucleosomes inhibit both transcriptional initiation and elongation by RNA polymerase III in vitro. EMBO J. 8:1989;2343-2351.
20. Pinaud S., Mirkovitch J. Regulation of c-fos expression by RNA polymerase elongation competence. J. Mol. Biol. 280:1998;785-798.
21. Plet A., Eick D., Blanchard J.M. Elongation and premature termination of transcripts initiated from c-fos and c-myc promoters show dissimilar patterns. Oncogene. 10:1995;319-328.
22. Quivy J.P., Becker P.B. The architecture of the heat-inducible Drosophila hsp27 promoter in nuclei. J. Mol. Biol. 256:1996;249-263.
23. Renz M., Neuberg M., Kurz C., Bravo R., Muller R. Regulation of c-fos transcription in mouse fibroblasts: identification of DNaseI hypersensitive sites and regulatory upstream sequences. EMBO J. 4:1985;3711-3716.
24. Robertson L.M., Kerppola T.K., Vendrell M., Luk D., Smeyne R.J., Bocchiaro C., Morgan J.I., Curran T. Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements. Neuron. 14:1995;241-252.
25. Rougvie A.E., Lis J.T. The RNA polymerase II molecule at the 5′ end of the uninduced hsp70 gene of D. melanogaster is transcriptionally engaged. Cell. 54:1988;795-804.
26. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning: A Laboratory Manual. second ed. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
27. Schild C., Claret F.X., Wahli W., Wolffe A.P. A nucleosome-dependent static loop potentiates estrogen-regulated transcription from the Xenopus vitellogenin B1 promoter in vitro. EMBO J. 12:1993;423-433.
28. Struhl K. Histone acetylation and transcriptional regulatory mechanisms. Genes Dev. 12:1998;599-606.
29. Studitsky V.M., Clark D.J., Felsenfeld G. Overcoming a nucleosomal barrier to transcription. Cell. 83:1995;19-27.
30. Thoma F. Nucleosome positioning. Biochim. Biophys. Acta. 1130:1992;1-19.
31. Treisman R. Journey to the surface of the cell: Fos regulation and the SRE. EMBO J. 14:1995;4905-4913.